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Showing 1 to 12 of 2536 entries
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Molecular Action and Clinical Relevance of Aromatase Inhibitors.

The oncologist

Murphy MJ.
PMID: 10388095
Oncologist. 1998;3(2):129-130.

BREAST CANCER: HIGH PREVALENCE AND RISING INCIDENCE: Breast cancer is the most common form of cancer among women in Europe, North and South America and Australasia; approximately 1 in 10 women in Western countries will develop breast cancer during...

Prevalence and Management of Diabetic Nephropathy in Western Countries.

Kidney diseases (Basel, Switzerland)

Satirapoj B, Adler SG.
PMID: 27536666
Kidney Dis (Basel). 2015 May;1(1):61-70. doi: 10.1159/000382028. Epub 2015 May 01.

BACKGROUND: Diabetic nephropathy (DN) often results in end-stage renal disease, and this is the most common reason for initiation of dialysis in the United States. Complications of diabetes, particularly renal disease, substantially increase the risk of subsequent severe illness...

Guidelines-similarities and dissimilarities: a systematic review of international clinical practice guidelines for pregnancy hypertension.

American journal of obstetrics and gynecology

Scott G, Gillon TE, Pels A, von Dadelszen P, Magee LA.
PMID: 32828743
Am J Obstet Gynecol. 2020 Aug 20; doi: 10.1016/j.ajog.2020.08.018. Epub 2020 Aug 20.

OBJECTIVE: This study aimed to review pregnancy hypertension clinical practice guidelines to inform international clinical practice and research priorities.STUDY ELIGIBILITY CRITERIA: Relevant national and international clinical practice guidelines, 2009-19, published in English, French, Dutch or German.STUDY APPRAISAL AND SYNTHESIS...

Clinical and Economic Impact of Hyperkalemia in Patients with Chronic Kidney Disease and Heart Failure.

Journal of managed care & specialty pharmacy

Polson M, Lord TC, Kangethe A, Speicher L, Farnum C, Brenner M, Oestreicher N, Alvarez P.
PMID: 28485202
J Manag Care Spec Pharm. 2017 Apr;23(4):S2-S9. doi: 10.18553/jmcp.2017.23.4-a.s2a.

BACKGROUND: Hyperkalemia (HK) is a concern for patients with chronic kidney disease (CKD) and heart failure (HF), and for those receiving treatments that inhibit the renin-angiotensin-aldosterone system (RAASi). An analysis of 1.7 million medical records of patients in the...

Effects of low-dose treatment with felodipine versus fosinopril in Chinese patients with nonischemic heart failure and normal blood pressure: A double-blind, randomized, crossover study.

Current therapeutic research, clinical and experimental

Lin MS, Chan KA, Wang CH, Chang NC.
PMID: 24936117
Curr Ther Res Clin Exp. 2004 Mar;65(2):204-21. doi: 10.1016/S0011-393X(04)90034-3.

BACKGROUND: Two second-generation calcium channel blockers, felodipine and amlodipine besylate, have been associated with similar high mortality rates in patients with ischemic heart failure (HF) but not in patients with nonischemic causes of HF. In patients with nonischemic HF,...

Association of Visit-to-Visit Variability in Kidney Function and Serum Electrolyte Indexes With Risk of Adverse Clinical Outcomes Among Patients With Heart Failure With Preserved Ejection Fraction.

JAMA cardiology

Segar MW, Patel RB, Patel KV, Fudim M, DeVore AD, Martens P, Hedayati SS, Grodin JL, Tang WHW, Pandey A.
PMID: 33206129
JAMA Cardiol. 2021 Jan 01;6(1):68-77. doi: 10.1001/jamacardio.2020.5592.

IMPORTANCE: Although kidney dysfunction and abnormalities in serum electrolyte levels are associated with poor clinical outcomes in patients with heart failure with preserved ejection fraction (HFpEF), the association of visit-to-visit variability in such laboratory measures with long-term outcomes is...

Balancing steroidal hormone cascade in treatment-resistant veteran soldiers with PTSD using a fermented soy product (FSWW08): a pilot study.

Hormone molecular biology and clinical investigation

Gocan AG, Bachg D, Schindler AE, Rohr UD.
PMID: 25436688
Horm Mol Biol Clin Investig. 2012 Jun;10(3):301-14. doi: 10.1515/hmbci-2011-0135.

UNLABELLED: Abstract Introduction: A clinical study was conducted to determine steroidal hormone cascade in the blood to relate them to mental performance with the Clinician-Administered PTSD scale (CAPS), serum lipid concentrations, and steroidal hormones, particularly cortisol, testosterone, estradiol, dehydroepiandrosterone...

Association of Visit-to-Visit Variability in Kidney Function and Serum Electrolyte Indexes With Risk of Adverse Clinical Outcomes Among Patients With Heart Failure With Preserved Ejection Fraction.

JAMA cardiology

Segar MW, Patel RB, Patel KV, Fudim M, DeVore AD, Martens P, Hedayati SS, Grodin JL, Tang WHW, Pandey A.
PMID: 33206129
JAMA Cardiol. 2021 Jan 01;6(1):68-77. doi: 10.1001/jamacardio.2020.5592.

IMPORTANCE: Although kidney dysfunction and abnormalities in serum electrolyte levels are associated with poor clinical outcomes in patients with heart failure with preserved ejection fraction (HFpEF), the association of visit-to-visit variability in such laboratory measures with long-term outcomes is...

Deciphering the Efficacy and Mechanisms of Chinese Herbal Medicine for Diabetic Kidney Disease by Integrating Web-Based Biochemical Databases and Real-World Clinical Data: Retrospective Cohort Study.

JMIR medical informatics

Wu CW, Chen HY, Yang CW, Chen YC.
PMID: 33973855
JMIR Med Inform. 2021 May 11;9(5):e27614. doi: 10.2196/27614.

BACKGROUND: Diabetic kidney disease (DKD) is one of the most crucial causes of chronic kidney disease (CKD). However, the efficacy and biomedical mechanisms of Chinese herbal medicine (CHM) for DKD in clinical settings remain unclear.OBJECTIVE: This study aimed to...

External Validation of a Prediction Model for Acute Kidney Injury Following Noncardiac Surgery.

JAMA network open

Nishimoto M, Murashima M, Kokubu M, Matsui M, Eriguchi M, Samejima KI, Akai Y, Tsuruya K.
PMID: 34661665
JAMA Netw Open. 2021 Oct 01;4(10):e2127362. doi: 10.1001/jamanetworkopen.2021.27362.

IMPORTANCE: The Simple Postoperative AKI Risk (SPARK) index is a prediction model for postoperative acute kidney injury (PO-AKI) in patients undergoing noncardiac surgery. External validation has not been performed.OBJECTIVE: To externally validate the SPARK index.DESIGN, SETTING, AND PARTICIPANTS: This...

External Validation of a Prediction Model for Acute Kidney Injury Following Noncardiac Surgery.

JAMA network open

Nishimoto M, Murashima M, Kokubu M, Matsui M, Eriguchi M, Samejima KI, Akai Y, Tsuruya K.
PMID: 34661665
JAMA Netw Open. 2021 Oct 01;4(10):e2127362. doi: 10.1001/jamanetworkopen.2021.27362.

IMPORTANCE: The Simple Postoperative AKI Risk (SPARK) index is a prediction model for postoperative acute kidney injury (PO-AKI) in patients undergoing noncardiac surgery. External validation has not been performed.OBJECTIVE: To externally validate the SPARK index.DESIGN, SETTING, AND PARTICIPANTS: This...

Clinical and laboratory determinants of low serum level of 25-hydroxyvitamin D during escalation of pharmacotherapy in heart failure patients.

Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery

Myrda K, Rozentryt P, Niedziela JT, Ociessa A, Kasperova M, Hudzik B, Nowak JU, Gąsior M.
PMID: 26702277
Kardiochir Torakochirurgia Pol. 2015 Sep;12(3):216-27. doi: 10.5114/kitp.2015.54457. Epub 2015 Sep 28.

INTRODUCTION: The activation of the renin-angiotensin-aldosterone (RAA) system is a main element of the pathophysiology of chronic heart failure (CHF), determining its symptoms and prognosis. Vitamin D is an RAA inhibitor, and its deficiency frequently accompanies CHF. The factors...

Showing 1 to 12 of 2536 entries