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Etiopathogenesis of Differentiated Thyroid Carcinomas.

Open access Macedonian journal of medical sciences

Makazlieva T, Vaskova O, Majstorov V.
PMID: 27703585
Open Access Maced J Med Sci. 2016 Sep 15;4(3):517-522. doi: 10.3889/oamjms.2016.086. Epub 2016 Aug 02.

INTRODUCTION: Thyroid malignomas are a heterogeneous group of neoplasm consisting of most frequent differentiated encountered carcinomas, papillary and follicular thyroid carcinoma, then medullary thyroid carcinoma originating from neuroendocrine calcitonin-producing C-cells and rare forms of thyroid lymphomas arising from intrathyroidal...

A second trigeminal CGRP receptor: function and expression of the AMY1 receptor.

Annals of clinical and translational neurology

Walker CS, Eftekhari S, Bower RL, Wilderman A, Insel PA, Edvinsson L, Waldvogel HJ, Jamaluddin MA, Russo AF, Hay DL.
PMID: 26125036
Ann Clin Transl Neurol. 2015 Jun;2(6):595-608. doi: 10.1002/acn3.197. Epub 2015 Apr 01.

OBJECTIVE: The trigeminovascular system plays a central role in migraine, a condition in need of new treatments. The neuropeptide, calcitonin gene-related peptide (CGRP), is proposed as causative in migraine and is the subject of intensive drug discovery efforts. This...

Combined Plasma and Cerebrospinal Fluid Signature for the Prediction of Midterm Progression From Mild Cognitive Impairment to Alzheimer Disease.

JAMA neurology

Lehallier B, Essioux L, Gayan J, Alexandridis R, Nikolcheva T, Wyss-Coray T, Britschgi M.
PMID: 26659895
JAMA Neurol. 2016 Feb;73(2):203-212. doi: 10.1001/jamaneurol.2015.3135. Epub 2015 Dec 14.

IMPORTANCE: A reliable method of detecting Alzheimer disease (AD) in its prodromal state is needed for patient stratification in clinical trials or for personalizing existing or potential upcoming therapies. Current cerebrospinal fluid (CSF)- or imaging-based single biomarkers for AD...

Management of Root Resorption Using Chemical Agents: A Review.

Iranian endodontic journal

Mohammadi Z, C Cehreli Z, Shalavi S, Giardino L, Palazzi F, Asgary S.
PMID: 26843869
Iran Endod J. 2016;11(1):1-7. doi: 10.7508/iej.2016.01.001. Epub 2015 Dec 24.

Root resorption (RR) is defined as the loss of dental hard tissues because of clastic activity inside or outside of tooth the root. In the permanent dentition, RR is a pathologic event; if untreated, it might result in the...

Genetic and Epigenetic of Medullary Thyroid Cancer.

Iranian biomedical journal

Khatami F, Tavangar SM.
PMID: 29126344
Iran Biomed J. 2018 May 01;22(3):142-50. doi: 10.22034/ibj.22.3.142. Epub 2017 Nov 11.

Medullary thyroid carcinoma (MTC) is an infrequent, calcitonin producing neuroendocrine tumor and initiates from the parafollicular C cells of the thyroid gland. Several genetic and epigenetic alterations are collaterally responsible for medullary thyroid carcinogenesis. In this review article, we...

The contribution of the genomes of a termite and a locust to our understanding of insect neuropeptides and neurohormones.

Frontiers in physiology

Veenstra JA.
PMID: 25477824
Front Physiol. 2014 Nov 19;5:454. doi: 10.3389/fphys.2014.00454. eCollection 2014.

The genomes of the migratory locust Locusta migratoria and the termite Zootermopsis nevadensis were mined for the presence of genes encoding neuropeptides, neurohormones, and their G-protein coupled receptors (GPCRs). Both species have retained a larger number of neuropeptide and...

CGRP antagonists and antibodies for the treatment of migraine.

Expert opinion on investigational drugs

Vécsei L, Szok D, Csáti A, Tajti J.
PMID: 25219387
Expert Opin Investig Drugs. 2015 Jan;24(1):31-41. doi: 10.1517/13543784.2015.960921. Epub 2014 Sep 15.

Introduction: Migraine is a highly devastating neurovascular disorder that affects up to 16% of the population worldwide. In spite of intensive research, its origin remains enigmatic with no therapeutic option appropriate for all migraine patients. One of the leading...

Association between calcitonin receptor .

Experimental and therapeutic medicine

Xiong Q, Xin L, Zhang L, Mao Z, Tang P.
PMID: 25452778
Exp Ther Med. 2015 Jan;9(1):65-76. doi: 10.3892/etm.2014.2083. Epub 2014 Nov 20.

The association between calcitonin receptor (CTR)

Hypercalcemia of Malignancy: An Update on Pathogenesis and Management.

North American journal of medical sciences

Mirrakhimov AE.
PMID: 26713296
N Am J Med Sci. 2015 Nov;7(11):483-93. doi: 10.4103/1947-2714.170600.

Hypercalcemia of malignancy is a common finding typically found in patients with advanced stage cancers. We aimed to provide an updated review on the etiology, pathogenesis, clinical presentation, and management of malignancy-related hypercalcemia. We searched PubMed/Medline, Scopus, Embase, and...

Esophageal recurrence of medullary thyroid carcinoma.

Gland surgery

Muñoz de Nova JL, Dworzynska A, Lorente-Poch L, Sancho JJ, Sitges-Serra A.
PMID: 26645011
Gland Surg. 2015 Dec;4(6):564-6. doi: 10.3978/j.issn.2227-684X.2015.03.04.

Medullary thyroid carcinoma (MTC) metastasizes to the regional lymph nodes and to the lungs, liver and bones. Only one case of recurrence of MTC involving the upper gastrointestinal tract has been reported so far. We describe the case of...

The dipeptidyl peptidase IV inhibitor vildagliptin suppresses development of neuropathy in diabetic rodents: effects on peripheral sensory nerve function, structure and molecular changes.

Journal of neurochemistry

Tsuboi K, Mizukami H, Inaba W, Baba M, Yagihashi S.
PMID: 26603140
J Neurochem. 2016 Feb;136(4):859-870. doi: 10.1111/jnc.13439. Epub 2016 Jan 11.

Incretin-related therapy was found to be beneficial for experimental diabetic neuropathy, but its mechanism is obscure. The purpose of this study is to explore the mechanism through which dipeptidyl peptidase IV inhibitor, vildagliptin (VG), influences neuropathy in diabetic rodents....

Effects of Chronic Hyperlipidemia on Lower Urinary Tract Function-Bladder Dysfunction in Myocardial Infarction-Prone Watanabe Heritable Hyperlipidemic Rabbits.

Lower urinary tract symptoms

Yoshida M, Kudoh J, Masunaga K, Nagata T, Shiomi M.
PMID: 26676696
Low Urin Tract Symptoms. 2012 Mar;4:21-6. doi: 10.1111/j.1757-5672.2011.00138.x.

To evaluate the effects of chronic hyperlipidemia on bladder function, we examined the functional and histological changes of the bladder in myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHL-MI) rabbits. Two age groups of WHHL-MI rabbits (6-12 months old, young WHHL-MI...

Showing 1 to 12 of 1473 entries