Gunasekara NS, Spencer CM.
CNS Drugs. 1998 Apr;9(4):325-40. doi: 10.2165/00023210-199809040-00007.
SYNOPSIS: Quetiapine, a dibenzothiazepine derivative, is one of several new 'atypical' antipsychotic agents. In preclinical studies, the drug was predicted to have antipsychotic efficacy and a low propensity to induce extrapyramidal effects. Quetiapine has been shown to be effective...
Revista medica del Instituto Mexicano del Seguro Social
Olvera-Acevedo A, Hurtado-Díaz J, Espinoza-Sánchez ML.
Rev Med Inst Mex Seguro Soc. 2020;58(4):517-521. doi: 10.24875/RMIMSS.M20000078.
INTRODUCCIÓN: Cuando inicia en el adulto, la enfermedad de Still es de mayor prevalencia en caucásicos y entre los 16 y 35 años. De etiología desconocida, se asocia a HLA-II, DR2, 4 y 7, y Bw35. El comienzo de...
Journal of obstetrics and gynaecology of India
Kapur A, Angomchanu R, Dey M.
J Obstet Gynaecol India. 2016 Oct;66:494-8. doi: 10.1007/s13224-016-0861-7. Epub 2016 Mar 18.
BACKGROUND: Fibroid or myoma is the commonest reported tumor of uterus, and is one of the important reasons for hysterectomy in our setting. Different drugs are available for medical management of fibroid uterus including mifepristone, a progesterone antagonist. Varying...
Hepatology research : the official journal of the Japan Society of Hepatology
Hepatol Res. 2005 Oct;33(2):167-70. doi: 10.1016/j.hepres.2005.09.027. Epub 2005 Sep 29.
Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a nuclear transcription factor that comprises the primary molecular target for thiazolidinedione (TZD) insulin-sensitizing drugs. Whilst expressed in many tissues in humans, its abundant expression in adipose tissue is believed to be the focal...
Bicho MD, Matos A, Silva AP, Macedo C, Afonso C, Areias MJ, Rebelo I.
Pregnancy Hypertens. 2012 Jul;2(3):325. doi: 10.1016/j.preghy.2012.04.270. Epub 2012 Jun 13.
INTRODUCTION: Preeclampsia may affect the risk for future cardiovascular disease. Haptoglobin (Hp), an acute phase protein with genetic polymorphism (Hp1.1, 2.1 and 2.2) synthesized in the hepatocyte and in many tissues, may modulate the risk through the antioxidant and...
Romanian journal of anaesthesia and intensive care
Tomescu D, Popescu M, Jipa L, Fota R, Ungureanu D, Zamfir R, Orban C, Dima SO, Popescu I.
Rom J Anaesth Intensive Care. 2016 Apr;23(1):19-26. doi: 10.21454/rjaic.7518.231.gft.
INTRODUCTION: The Donor Risk Index (DRI) has become a universal score for organ allocation in liver transplantation (LT) worldwide. The aim of this study was to evaluate the impact of liver graft quality measured by DRI, CIT, WIT and...
Indian journal of clinical biochemistry : IJCB
Shah H, Haridas N.
Indian J Clin Biochem. 2003 Jul;18(2):93-101. doi: 10.1007/BF02867373.
Laboratory infarction diagnostics are based on the detection of elevated serum activities of total Creatine Kinase (CK), Creatine Kinase isoensyme MB, (CKMB), Lactate dehydrogenase (LDH), isoenzyme forms of LDH and transaminases. Determination of these cardiac marker enzymes permits a...
Frontiers in physiology
Neuman MG, Mueller J, Mueller S.
Front Physiol. 2021 Jul 07;12:678118. doi: 10.3389/fphys.2021.678118. eCollection 2021.
INTRODUCTION: Alcohol-related liver disease (ALD) represents the most common liver disease worldwide, however, the underlying molecular mechanisms are still poorly understood. Namely centrilobular inflammation and programmed cell death are characteristic to ALD and it remains to be elucidated why...
Oncology research and treatment
Oncol Res Treat. 2021 Dec 16; doi: 10.1159/000521499. Epub 2021 Dec 16.
Background Despite the advances that have been made to improve conventional chemotherapies, their use is limited by a narrow therapeutic window based on off-target toxicities. Antibody-drug-conjugates (ADCs) are composed of an antibody and a toxic payload covalently coupled by...
Ashour H, Rashed L, Elkordy MA, Abdelwahed OM.
Exp Physiol. 2021 Nov;106(11):2262-2275. doi: 10.1113/EP089765. Epub 2021 Oct 25.
NEW FINDINGS: What is the central question of this study? What is the role of circulating exosomal miR-687 in remote hepatic injury following renal ischaemia-reperfusion injury (IRI) and does thymoquinone have a modulatory impact? What is the main finding...
Biotechnology and bioengineering
Bonarius HP, Hatzimanikatis V, Meesters KP, de Gooijer CD, Schmid G, Tramper J.
Biotechnol Bioeng. 1996 May 05;50(3):299-318. doi: 10.1002/(SICI)1097-0290(19960505)50:3<299::AID-BIT9>3.0.CO;2-B.
The estimation of the intracellular fluxes of mammalian cells using only the mass balances of the relevant metabolites is not possible because the set of linear equations defined by these mass balances is underdetermined. Either additional experimental flux data...
Indian journal of clinical biochemistry : IJCB
Naik P, Sritharan V, Bandi P, Madhavarapu M.
Indian J Clin Biochem. 2013 Jan;28(1):38-45. doi: 10.1007/s12291-012-0245-4. Epub 2012 Aug 17.
Liver transplantation means surgical replacement of a diseased liver with a healthy liver. The survival rate used to be 30 % after 1 year and LTx was considered to be the last procedure when all medical or surgical intervention...