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Showing 1 to 12 of 950 entries
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Quetiapine : A Review of its Use in Schizophrenia.

CNS drugs

Gunasekara NS, Spencer CM.
PMID: 27521016
CNS Drugs. 1998 Apr;9(4):325-40. doi: 10.2165/00023210-199809040-00007.

SYNOPSIS: Quetiapine, a dibenzothiazepine derivative, is one of several new 'atypical' antipsychotic agents. In preclinical studies, the drug was predicted to have antipsychotic efficacy and a low propensity to induce extrapyramidal effects. Quetiapine has been shown to be effective...

Still's disease: a rare condition, in a patient of unusual age.

Revista medica del Instituto Mexicano del Seguro Social

Olvera-Acevedo A, Hurtado-Díaz J, Espinoza-Sánchez ML.
PMID: 34543559
Rev Med Inst Mex Seguro Soc. 2020;58(4):517-521. doi: 10.24875/RMIMSS.M20000078.

INTRODUCCIÓN: Cuando inicia en el adulto, la enfermedad de Still es de mayor prevalencia en caucásicos y entre los 16 y 35 años. De etiología desconocida, se asocia a HLA-II, DR2, 4 y 7, y Bw35. El comienzo de...

Efficacy of Use of Long-Term, Low-Dose Mifepristone for the Treatment of Fibroids.

Journal of obstetrics and gynaecology of India

Kapur A, Angomchanu R, Dey M.
PMID: 27651652
J Obstet Gynaecol India. 2016 Oct;66:494-8. doi: 10.1007/s13224-016-0861-7. Epub 2016 Mar 18.

BACKGROUND: Fibroid or myoma is the commonest reported tumor of uterus, and is one of the important reasons for hysterectomy in our setting. Different drugs are available for medical management of fibroid uterus including mifepristone, a progesterone antagonist. Varying...

Thiazolidinediones: Pleiotropic drugs with potent anti-inflammatory properties for tissue protection.

Hepatology research : the official journal of the Japan Society of Hepatology

Buckingham RE.
PMID: 16198619
Hepatol Res. 2005 Oct;33(2):167-70. doi: 10.1016/j.hepres.2005.09.027. Epub 2005 Sep 29.

Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a nuclear transcription factor that comprises the primary molecular target for thiazolidinedione (TZD) insulin-sensitizing drugs. Whilst expressed in many tissues in humans, its abundant expression in adipose tissue is believed to be the focal...

PP159. In women with previous pregnancy hypertension, cardiovascular risk biomarkers may be modulated by haptoglobin genotype.

Pregnancy hypertension

Bicho MD, Matos A, Silva AP, Macedo C, Afonso C, Areias MJ, Rebelo I.
PMID: 26105480
Pregnancy Hypertens. 2012 Jul;2(3):325. doi: 10.1016/j.preghy.2012.04.270. Epub 2012 Jun 13.

INTRODUCTION: Preeclampsia may affect the risk for future cardiovascular disease. Haptoglobin (Hp), an acute phase protein with genetic polymorphism (Hp1.1, 2.1 and 2.2) synthesized in the hepatocyte and in many tissues, may modulate the risk through the antioxidant and...

The impact of donor liver graft quality on postoperative outcome in liver transplant recipients. A single centre experience.

Romanian journal of anaesthesia and intensive care

Tomescu D, Popescu M, Jipa L, Fota R, Ungureanu D, Zamfir R, Orban C, Dima SO, Popescu I.
PMID: 28913473
Rom J Anaesth Intensive Care. 2016 Apr;23(1):19-26. doi: 10.21454/rjaic.7518.231.gft.

INTRODUCTION: The Donor Risk Index (DRI) has become a universal score for organ allocation in liver transplantation (LT) worldwide. The aim of this study was to evaluate the impact of liver graft quality measured by DRI, CIT, WIT and...

Evaluation of clinical utility of serum enzymes and troponin-T in the early stages of acute myocardial infarction.

Indian journal of clinical biochemistry : IJCB

Shah H, Haridas N.
PMID: 23105398
Indian J Clin Biochem. 2003 Jul;18(2):93-101. doi: 10.1007/BF02867373.

Laboratory infarction diagnostics are based on the detection of elevated serum activities of total Creatine Kinase (CK), Creatine Kinase isoensyme MB, (CKMB), Lactate dehydrogenase (LDH), isoenzyme forms of LDH and transaminases. Determination of these cardiac marker enzymes permits a...

Non-invasive Biomarkers of Liver Inflammation and Cell Death in Response to Alcohol Detoxification.

Frontiers in physiology

Neuman MG, Mueller J, Mueller S.
PMID: 34305638
Front Physiol. 2021 Jul 07;12:678118. doi: 10.3389/fphys.2021.678118. eCollection 2021.

INTRODUCTION: Alcohol-related liver disease (ALD) represents the most common liver disease worldwide, however, the underlying molecular mechanisms are still poorly understood. Namely centrilobular inflammation and programmed cell death are characteristic to ALD and it remains to be elucidated why...

Antibody-Drug-Conjugates for Breast Cancer.

Oncology research and treatment

Marmé F.
PMID: 34915488
Oncol Res Treat. 2021 Dec 16; doi: 10.1159/000521499. Epub 2021 Dec 16.

Background Despite the advances that have been made to improve conventional chemotherapies, their use is limited by a narrow therapeutic window based on off-target toxicities. Antibody-drug-conjugates (ADCs) are composed of an antibody and a toxic payload covalently coupled by...

Remote liver injury following acute renal ischaemia-reperfusion: involvement of circulating exosomal miR-687 and regulation by thymoquinone.

Experimental physiology

Ashour H, Rashed L, Elkordy MA, Abdelwahed OM.
PMID: 34633737
Exp Physiol. 2021 Nov;106(11):2262-2275. doi: 10.1113/EP089765. Epub 2021 Oct 25.

NEW FINDINGS: What is the central question of this study? What is the role of circulating exosomal miR-687 in remote hepatic injury following renal ischaemia-reperfusion injury (IRI) and does thymoquinone have a modulatory impact? What is the main finding...

Metabolic flux analysis of hybridoma cells in different culture media using mass balances.

Biotechnology and bioengineering

Bonarius HP, Hatzimanikatis V, Meesters KP, de Gooijer CD, Schmid G, Tramper J.
PMID: 18626958
Biotechnol Bioeng. 1996 May 05;50(3):299-318. doi: 10.1002/(SICI)1097-0290(19960505)50:3<299::AID-BIT9>3.0.CO;2-B.

The estimation of the intracellular fluxes of mammalian cells using only the mass balances of the relevant metabolites is not possible because the set of linear equations defined by these mass balances is underdetermined. Either additional experimental flux data...

A single centre prospective study of liver function tests in post liver transplant patients.

Indian journal of clinical biochemistry : IJCB

Naik P, Sritharan V, Bandi P, Madhavarapu M.
PMID: 24381419
Indian J Clin Biochem. 2013 Jan;28(1):38-45. doi: 10.1007/s12291-012-0245-4. Epub 2012 Aug 17.

Liver transplantation means surgical replacement of a diseased liver with a healthy liver. The survival rate used to be 30 % after 1 year and LTx was considered to be the last procedure when all medical or surgical intervention...

Showing 1 to 12 of 950 entries