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Conserved Structure and Evolution of DPF Domain of PHF10-The Specific Subunit of PBAF Chromatin Remodeling Complex.

International journal of molecular sciences

Chugunov AO, Potapova NA, Klimenko NS, Tatarskiy VV, Georgieva SG, Soshnikova NV.
PMID: 34681795
Int J Mol Sci. 2021 Oct 15;22(20). doi: 10.3390/ijms222011134.

Transcription activation factors and multisubunit coactivator complexes get recruited at specific chromatin sites via protein domains that recognize histone modifications. Single PHDs (plant homeodomains) interact with differentially modified H3 histone tails. Double PHD finger (DPF) domains possess a unique...

Phenylpropanoids as master regulators: state of the art and perspectives in common bean (Phaseolus vulgaris).

Frontiers in plant science

Valdés-López O, Hernández G.
PMID: 25101096
Front Plant Sci. 2014 Jul 17;5:336. doi: 10.3389/fpls.2014.00336. eCollection 2014.

No abstract available.

The two faces of Janus kinases and their respective STATs in mammary gland development and cancer.

Journal of carcinogenesis

Wagner KU, Schmidt JW.
PMID: 22279417
J Carcinog. 2011;10:32. doi: 10.4103/1477-3163.90677. Epub 2011 Dec 08.

Since its discovery as "just another kinase" more than twenty years ago, the family of JAK tyrosine kinases and their respective Signal Transducers and Activators of Transcription (STATs) has been a center of attention in the areas of signal...

Regulation of stellate cell proliferation by lipopolysaccharide: Role of endogenous nitric oxide.

Journal of gastroenterology and hepatology

Kawada N, Seki S, Kuroki T, Inoue M.
PMID: 28976688
J Gastroenterol Hepatol. 1998 Sep;13:S6-S13. doi: 10.1111/jgh.1998.13.s1.6.

We studied the effect of lipopolysaccharide (LPS) on the proliferation of culture-stimulated rat stellate cells. DNA synthesis as determined by [

Browning and Graying: Novel Transcriptional Regulators of Brown and Beige Fat Tissues and Aging.

Frontiers in endocrinology

Mueller E.
PMID: 26973598
Front Endocrinol (Lausanne). 2016 Mar 02;7:19. doi: 10.3389/fendo.2016.00019. eCollection 2016.

Obesity represents a major risk factor for the development of a number of metabolic disorders, including cardiovascular disease and type 2 diabetes. Since the discovery that brown and beige fat cells exist in adult humans and contribute to energy...

From Locus Association to Mechanism of Gene Causality: The Devil Is in the Details.

Arteriosclerosis, thrombosis, and vascular biology

Miller CL, Pjanic M, Quertermous T.
PMID: 26399919
Arterioscler Thromb Vasc Biol. 2015 Oct;35(10):2079-2080. doi: 10.1161/ATVBAHA.115.306366.

No abstract available.

Drug Repurposing of the Anthelmintic Niclosamide to Treat Multidrug-Resistant Leukemia.

Frontiers in pharmacology

Hamdoun S, Jung P, Efferth T.
PMID: 28344555
Front Pharmacol. 2017 Mar 10;8:110. doi: 10.3389/fphar.2017.00110. eCollection 2017.

Multidrug resistance, a major problem that leads to failure of anticancer chemotherapy, requires the development of new drugs. Repurposing of established drugs is a promising approach for overcoming this problem. An example of such drugs is niclosamide, a known...

Polymorphism of Transcription Factor-7-Like 2 (TCF7L2) Gene and New-Onset Diabetes after Liver Transplantation.

International journal of organ transplantation medicine

Musavi Z, Azarpira N, Sangtarash MH, Kordi M, Kazemi K, Geramizadeh B, Malek-Hosseini SA.
PMID: 25737773
Int J Organ Transplant Med. 2015;6(1):14-22.

BACKGROUND: New-onset diabetes after transplantation (NODAT) is a serious complication in transplant recipients. Transcription factor-7-like 2 (TCF7L2) is a Wnt signaling-associated transcription factor that plays an important role in β-cell proliferation and insulin secretion. The association between TCF7L2 SNP...

NF-KappaB in Long-Term Memory and Structural Plasticity in the Adult Mammalian Brain.

Frontiers in molecular neuroscience

Kaltschmidt B, Kaltschmidt C.
PMID: 26635522
Front Mol Neurosci. 2015 Nov 24;8:69. doi: 10.3389/fnmol.2015.00069. eCollection 2015.

The transcription factor nuclear factor kappaB (NF-κB) is a well-known regulator of inflammation, stress, and immune responses as well as cell survival. In the nervous system, NF-κB is one of the crucial components in the molecular switch that converts...

Investigating the role of introns in the regulation of regenerating gene 1 expression.

Oncology letters

Chai Y, Sun Y, Guo L, Li D, Ding Y.
PMID: 25621062
Oncol Lett. 2015 Feb;9(2):875-880. doi: 10.3892/ol.2014.2712. Epub 2014 Nov 19.

Gastrin is a hormone that physiologically regulates gastric acid secretion and contributes to the maintenance of gastric epithelial architecture by regulating the expression of genes such as regenerating gene 1 (

Mining expressed sequence tags of rapeseed (Brassica napus L.) to predict the drought responsive regulatory network.

Physiology and molecular biology of plants : an international journal of functional plant biology

Shamloo-Dashtpagerdi R, Razi H, Ebrahimie E.
PMID: 26261397
Physiol Mol Biol Plants. 2015 Jul;21(3):329-40. doi: 10.1007/s12298-015-0311-5. Epub 2015 Jul 02.

It is of great significance to understand the regulatory mechanisms by which plants deal with drought stress. Two EST libraries derived from rapeseed (Brassica napus) leaves in non-stressed and drought stress conditions were analyzed in order to obtain the...

The .

Frontiers in microbiology

Gundogdu O, da Silva DT, Mohammad B, Elmi A, Wren BW, van Vliet AH, Dorrell N.
PMID: 28082970
Front Microbiol. 2016 Dec 26;7:2117. doi: 10.3389/fmicb.2016.02117. eCollection 2016.

No abstract available.

Showing 1 to 12 of 11127 entries