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Otol Neurotol. 2003 Jul;24(4):543-7. doi: 10.1097/00129492-200307000-00003.

Ossiculoplasty with total hydroxylapatite prostheses anatomical and functional outcomes.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Eric Rondini-Gilli, Alexis Bozorg Grayeli, Paulo Fernando Tormin Borges Crosara, Hani El Garem, Isabelle Mosnier, Didier Bouccara, Olivier Sterkers


  1. Otolaryngology-Head and Neck Surgery Department, Hôpital Beaujon, AP-HP, and INSERM EMI-U 0112, Faculté Xavier Bichat, Université Paris 7, France.

PMID: 12851543 DOI: 10.1097/00129492-200307000-00003


OBJECTIVE: To evaluate the results of partial and total ossicular reconstruction prostheses entirely made of hydroxylapatite.

STUDY DESIGN: A retrospective review of cases followed-up between 1997 and 2000.

SETTING: Tertiary referral center.

PATIENTS: One hundred adult patients (60 men and 40 women) were studied. The mean age was 55 years (range, 25 to 65 years). Fifty patients had a previous tympanoplasty. The series included 45 cholesteatomas (45%), 37 chronic otitis media without cholesteatoma (37%), 13 retraction pockets (13%), and 5 posttraumatic ossicular displacements (5%).

INTERVENTION: A one-stage ossiculoplasty with a partial ossicular reconstruction prosthesis (n = 65) or a total ossicular reconstruction prosthesis (n = 35) was performed. This was associated with a simple mastoidectomy in 70 cases and a radical mastoidectomy in 10 cases.

MAIN OUTCOME MEASURES: All patients were followed-up at 1 year, and 50 were reexamined 2 years after surgery. Clinical and audiometric data were collected in a database at each visit.

RESULTS: A prosthetic extrusion was noted in two cases (2%). A prosthetic displacement occurred in 10 cases (10%). A revision surgery was carried out in 10 cases because of an ossiculoplasty failure or a disease recurrence. At 1 year, the residual air-bone gap was lower in cases with a partial ossicular reconstruction prosthesis than those with a total ossicular reconstruction prosthesis (16 +/- 9.3 versus 23 +/- 13.7 dB, p < 0.05). The gain in mean air conduction threshold was 21 +/- 12.8 dB in cases of partial ossicular reconstruction prosthesis and 19 +/- 11.3 dB in cases of total ossicular reconstruction prosthesis (not significant). Revision surgery, canal wall-down mastoidectomy, or cholesteatoma yielded poorer functional results.

CONCLUSION: Partial ossicular reconstruction prosthesis and total ossicular reconstruction prosthesis entirely made of dense hydroxylapatite yielded high rates of air-bone gap reduction and high anatomic stability.


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