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J Am Soc Nephrol. 1992 Aug;3(2):157-61. doi: 10.1681/ASN.V32157.

Growth hormone and the kidney: a case presentation and review of the literature.

Journal of the American Society of Nephrology : JASN

M H O'Shea, D T Layish


  1. Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.

PMID: 1391716 DOI: 10.1681/ASN.V32157
Free Article


Hypersomatotropism is accompanied by a significant increase in GFR and RPF. A case of a patient with acromegaly and supranormal renal function as measured by inulin and p-aminohippurate clearances is reported. The literature regarding the effects of growth hormone on renal function is reviewed, and the potential mechanisms of action and therapeutic implications of these effects are discussed.

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