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Elsevier Science

Gastroenterology. 1990 Sep;99(3):854-6. doi: 10.1016/0016-5085(90)90980-f.

Chronic cholestasis, paucity of bile ducts, red cell aplasia, and the Stevens-Johnson syndrome. An ampicillin-associated case.


F J Cavanzo, C F Garcia, R C Botero


  1. Department of Pathology, Fundación Santa Fé de Bogotá, Colombia.

PMID: 2116345 DOI: 10.1016/0016-5085(90)90980-f


The unique case of severe chronic cholestasis with paucity of bile ducts accompanied by pure red cell aplasia and the Stevens-Johnson syndrome in a 35-year-old woman after ampicillin ingestion is presented. The patient improved gradually and is asymptomatic 4 years later. Sequential histological and clinical follow-up substantiate the course of her disease.

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