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United European Gastroenterol J. 2017 Oct;5(6):805-810. doi: 10.1177/2050640616684698. Epub 2017 Jan 18.

Subtypes of chronic gastritis in patients with celiac disease before and after gluten-free diet.

United European gastroenterology journal

Dolores Gabrieli, Fabiana Ciccone, Annalisa Capannolo, Angelo Viscido, Giorgio Valerii, Donatella Serva, Stefano Necozione, Gino Coletti, Giuseppe Calvisi, Dina Melideo, Giuseppe Frieri, Giovanni Latella

Affiliations

  1. Gastroenterology Unit, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
  2. Epidemiology Unit, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
  3. Pathology Unit, S. Salvatore Hospital, L'Aquila, Italy.

PMID: 29026594 PMCID: PMC5625871 DOI: 10.1177/2050640616684698

Abstract

BACKGROUND: Celiac disease (CD) often manifests with dyspeptic symptoms and chronic gastritis is a common finding.

AIM: To evaluate the frequency of lymphocytic gastritis (LG), chronic active gastritis (CAG), and chronic inactive gastritis (CIG) in patients with CD, before and after gluten-free diet (GFD).

METHODS: A five-year prospective study including all consecutive patients with a new diagnosis of CD was conducted. Gastric and duodenal biopsy specimens taken both at the time of the CD diagnosis and at the first endoscopic control after 18-24 months on GFD were evaluated.

RESULTS: 213 patients with CD were enrolled. At the time of the diagnosis, 42 patients (19.7%) showed normal gastric mucosa, 34 (15.9%) LG, 67 (31.5%) CAG, and 70 (32.9%) CIG. Out of the 34 patients with LG, all were

CONCLUSIONS: LG is present in 16% of CD patients, it is not associated with

Keywords: Celiac disease; chronic active gastritis; chronic inactive gastritis; lymphocytic gastritis

References

  1. Gastroenterol Hepatol Bed Bench. 2015 Spring;8(2):99-109 - PubMed
  2. J Pediatr Gastroenterol Nutr. 2008 Nov;47(5):568-72 - PubMed
  3. J Clin Pathol. 1998 Mar;51(3):207-10 - PubMed
  4. Am J Surg Pathol. 1996 Jul;20(7):865-70 - PubMed
  5. Pediatr Dev Pathol. 2011 Jul-Aug;14(4):280-3 - PubMed
  6. Aliment Pharmacol Ther. 2015 Jul;42(2):180-7 - PubMed
  7. J Clin Pathol. 1995 Oct;48(10):939-45 - PubMed
  8. Helicobacter. 2014 Oct;19(5):349-55 - PubMed
  9. Aliment Pharmacol Ther. 2011 Jun;33(12):1340-9 - PubMed
  10. Am J Surg Pathol. 1996 Oct;20(10):1161-81 - PubMed
  11. Hum Pathol. 2016 Apr;50:127-34 - PubMed
  12. Mediators Inflamm. 2007;2007:81838 - PubMed
  13. Am J Clin Pathol. 2012 Jul;138(1):42-9 - PubMed
  14. Clin Gastroenterol Hepatol. 2009 Nov;7(11):1210-6 - PubMed
  15. Gastroenterology. 1992 Jan;102(1):330-54 - PubMed
  16. Gastroenterology. 1990 Feb;98(2):310-5 - PubMed
  17. Am J Gastroenterol. 2013 May;108(5):656-76; quiz 677 - PubMed
  18. J Pediatr. 1994 Jan;124(1):57-62 - PubMed
  19. Gut. 1999 Oct;45(4):495-8 - PubMed
  20. Pathologe. 2001 Jan;22(1):56-61 - PubMed
  21. Aliment Pharmacol Ther. 2006 Jun 1;23(11):1525-34 - PubMed
  22. Hum Pathol. 1990 Nov;21(11):1092-6 - PubMed

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