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Chatterjee A, Rai S, Guddattu V, et al. Is methicillin-resistant . Risk Manag Healthc Policy. 2018;11:243-250doi: 10.2147/RMHP.S176517.
Chatterjee, A., Rai, S., Guddattu, V., Mukhopadhyay, C., & Saravu, K. (2018). Is methicillin-resistant . Risk management and healthcare policy, 11243-250. https://doi.org/10.2147/RMHP.S176517
Chatterjee, Aparajita, et al. "Is methicillin-resistant ." Risk management and healthcare policy vol. 11 (2018): 243-250. doi: https://doi.org/10.2147/RMHP.S176517
Chatterjee A, Rai S, Guddattu V, Mukhopadhyay C, Saravu K. Is methicillin-resistant . Risk Manag Healthc Policy. 2018 Dec 03;11:243-250. doi: 10.2147/RMHP.S176517. eCollection 2018. PMID: 30584380; PMCID: PMC6284536.
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Risk Manag Healthc Policy. 2018 Dec 03;11:243-250. doi: 10.2147/RMHP.S176517. eCollection 2018.

Is methicillin-resistant .

Risk management and healthcare policy

Aparajita Chatterjee, Shipra Rai, Vasudeva Guddattu, Chiranjay Mukhopadhyay, Kavitha Saravu

Affiliations

  1. Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Madhav Nagar, Karnataka, India, [email protected], [email protected].
  2. Department of Statistics, Prasanna School of Public Health, Manipal Academy of Higher Education (MAHE), Manipal, Madhav Nagar, Karnataka, India.
  3. Department of Microbiology, Kasturba Medical College Manipal Academy of Higher Education (MAHE), Manipal, Madhav Nagar, Karnataka, India.
  4. Manipal McGill Center for Infectious Diseases, Prasanna School of Public Health, Manipal Academy of Higher Education (MAHE), Manipal, Madhav Nagar, Karnataka, India, [email protected].

PMID: 30584380 PMCID: PMC6284536 DOI: 10.2147/RMHP.S176517

Abstract

PURPOSE: To determine morbidity and mortality of methicillin-resistant

METHODS: A cohort study among hospitalized adult patients with culture proven MRSA or MSSA monoinfection were recruited in a tertiary referral center in South India from November 2011 to December 2012.

RESULTS: Of total 551 subjects, 284 (52%) had MRSA and 267 (48%) MSSA infection. A total of 184 (65%) subjects had health care-associated MRSA (HA-MRSA) and 100 (35%) community-associated MRSA (CA-MRSA). Chronic kidney disease and recent antibiotic use had significant association with MRSA. MRSA patients had significant respiratory infection (OR 2.24 [1.04, 5.16]) and bacteremia (OR 2.24 [10.40, 5.16]), relative to MSSA. MSSA group had better survival function compared to MRSA group (

CONCLUSION: MRSA imposes a huge burden in Indian scenario and HA-MRSA remains the main culprit. Patients with history of chronic kidney disease and recent use of antibiotics were found to be at a higher risk. Patients with MRSA infections tend to have poorer outcomes in terms of longer hospital stay, greater complications, and mortality.

Keywords: India; Staphylococcus aureus; impact; methicillin-resistant Staphylococcus aureus; morbidity; mortality; outcome; prognosis; risk factors

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

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