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Li Q, Zhang Q, Zhang S, et al. Relationship between frailty and cognitive decline in Chinese older patients with Alzheimer's disease: The mediating role of social contact. Geriatr Nurs. 2021;43:175-181doi: 10.1016/j.gerinurse.2021.11.019.
Li, Q., Zhang, Q., Zhang, S., Du, M., Wang, X., Hu, S., & Li, L. (2021). Relationship between frailty and cognitive decline in Chinese older patients with Alzheimer's disease: The mediating role of social contact. Geriatric nursing (New York, N.Y.), 43175-181. https://doi.org/10.1016/j.gerinurse.2021.11.019
Li, Qingfeng, et al. "Relationship between frailty and cognitive decline in Chinese older patients with Alzheimer's disease: The mediating role of social contact." Geriatric nursing (New York, N.Y.) vol. 43 (2021): 175-181. doi: https://doi.org/10.1016/j.gerinurse.2021.11.019
Li Q, Zhang Q, Zhang S, Du M, Wang X, Hu S, Li L. Relationship between frailty and cognitive decline in Chinese older patients with Alzheimer's disease: The mediating role of social contact. Geriatr Nurs. 2021 Dec 12;43:175-181. doi: 10.1016/j.gerinurse.2021.11.019. Epub 2021 Dec 12. PMID: 34911018.
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Geriatr Nurs. 2021 Dec 12;43:175-181. doi: 10.1016/j.gerinurse.2021.11.019. Epub 2021 Dec 12.

Relationship between frailty and cognitive decline in Chinese older patients with Alzheimer's disease: The mediating role of social contact.

Geriatric nursing (New York, N.Y.)

Qingfeng Li, Qianqian Zhang, Shuping Zhang, Mingchao Du, Xia Wang, Shaohua Hu, Lunlan Li

Affiliations

  1. Department of Nursing, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
  2. Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
  3. Department of Emergency Surgery, The Fourth Affiliated Hospital of Anhui Medical University, Hefei 230011, China.
  4. Department of Information Centre, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
  5. Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
  6. Department of Personnel, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China. Electronic address: [email protected].

PMID: 34911018 DOI: 10.1016/j.gerinurse.2021.11.019

Abstract

This study aimed to evaluate the effects of frailty and social contact on cognitive decline among Chinese older patients with Alzheimer's disease (AD), and examine the mediating role of social contact between frailty and cognitive decline. A total of 205 eligible participants were recruited from a tertiary A hospital in Anhui province, China. A structural equation modeling was conducted to test the hypothetical mediating model. Frailty and cognitive decline were significantly and negatively correlated with social contact. Meanwhile, frailty exerted a significant positive effect on cognitive decline. The indirect effect of frailty on the cognitive decline through social contact was 0.401. Social contact could exert a partial mediating effect on the relationship between frailty and cognitive decline in this population. These findings could help guide effective interventions to improve the cognitive abilities of AD patients, thereby reducing the burden of this population on their caregivers.

Copyright © 2021 Elsevier Inc. All rights reserved.

Keywords: Alzheimer's disease; Cognitive decline; Frailty; Social contact

Conflict of interest statement

Declaration of Competing Interest None

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