Display options
Cite
Radchenko V, Morgenstern A, Jalilian AR, et al. Production and Supply of α-Particle-Emitting Radionuclides for Targeted α-Therapy. J Nucl Med. 2021;62(11):1495-1503doi: 10.2967/jnumed.120.261016.
Radchenko, V., Morgenstern, A., Jalilian, A. R., Ramogida, C. F., Cutler, C., Duchemin, C., Hoehr, C., Haddad, F., Bruchertseifer, F., Gausemel, H., Yang, H., Osso, J. A., Washiyama, K., Czerwinski, K., Leufgen, K., Pruszyński, M., Valzdorf, O., Causey, P., Schaffer, P., Perron, R., Maxim, S., Wilbur, D. S., Stora, T., & Li, Y. (2021). Production and Supply of α-Particle-Emitting Radionuclides for Targeted α-Therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 62(11), 1495-1503. https://doi.org/10.2967/jnumed.120.261016
Radchenko, Valery, et al. "Production and Supply of α-Particle-Emitting Radionuclides for Targeted α-Therapy." Journal of nuclear medicine : official publication, Society of Nuclear Medicine vol. 62,11 (2021): 1495-1503. doi: https://doi.org/10.2967/jnumed.120.261016
Radchenko V, Morgenstern A, Jalilian AR, Ramogida CF, Cutler C, Duchemin C, Hoehr C, Haddad F, Bruchertseifer F, Gausemel H, Yang H, Osso JA, Washiyama K, Czerwinski K, Leufgen K, Pruszyński M, Valzdorf O, Causey P, Schaffer P, Perron R, Maxim S, Wilbur DS, Stora T, Li Y. Production and Supply of α-Particle-Emitting Radionuclides for Targeted α-Therapy. J Nucl Med. 2021 Nov;62(11):1495-1503. doi: 10.2967/jnumed.120.261016. Epub 2021 Jul 22. PMID: 34301779; PMCID: PMC8612335.
Copy Download .nbib Format: NLM
Share it on

J Nucl Med. 2021 Nov;62(11):1495-1503. doi: 10.2967/jnumed.120.261016. Epub 2021 Jul 22.

Production and Supply of α-Particle-Emitting Radionuclides for Targeted α-Therapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Valery Radchenko, Alfred Morgenstern, Amir R Jalilian, Caterina F Ramogida, Cathy Cutler, Charlotte Duchemin, Cornelia Hoehr, Ferrid Haddad, Frank Bruchertseifer, Haavar Gausemel, Hua Yang, Joao Alberto Osso, Kohshin Washiyama, Kenneth Czerwinski, Kirsten Leufgen, Marek Pruszyński, Olga Valzdorf, Patrick Causey, Paul Schaffer, Randy Perron, Samsonov Maxim, D Scott Wilbur, Thierry Stora, Yawen Li

Affiliations

  1. Life Sciences Division, TRIUMF, Vancouver, British Columbia, Canada; [email protected].
  2. Department of Chemistry, University of British Columbia, Vancouver, British Columbia, Canada.
  3. European Commission, Joint Research Centre, Karlsruhe, Germany.
  4. International Atomic Energy Agency, Vienna, Austria.
  5. Life Sciences Division, TRIUMF, Vancouver, British Columbia, Canada.
  6. Simon Fraser University, Burnaby, British Columbia, Canada.
  7. Collider Accelerator Department, Brookhaven National Laboratory, Upton, New York.
  8. CERN, Geneva, Switzerland.
  9. Institute for Nuclear and Radiation Physics, KU Leuven, Heverlee, Belgium.
  10. Arronax, Nantes, France.
  11. Bayer American Samoa, Oslo, Norway.
  12. Advanced Clinical Research Center, Fukushima Medical University, Fukushima, Japan.
  13. Radiochemistry Program, Department of Chemistry, University of Nevada, Las Vegas, Nevada.
  14. SCIPROM Sarl, Saint-Sulpice, Switzerland.
  15. Institute of Nuclear Chemistry and Technology, Warsaw, Poland.
  16. NOMATEN Centre of Excellence, National Centre for Nuclear Research, Otwock, Poland.
  17. Isotope JSC, Rosatom State Corp., Moscow, Russian Federation.
  18. BWXT Medical Ltd., Ottawa, Ontario, Canada.
  19. Canadian Nuclear Laboratories, Chalk River, Ontario, Canada.
  20. State Scientific Centre of the Russian Federation, Leypunsky Institute for Physics and Power Engineering, Rosatom State Corp., Obninsk, Russian Federation; and.
  21. Department of Radiation Oncology, University of Washington, Seattle, Washington.

PMID: 34301779 PMCID: PMC8612335 DOI: 10.2967/jnumed.120.261016

Abstract

Encouraging results from targeted α-therapy have received significant attention from academia and industry. However, the limited availability of suitable radionuclides has hampered widespread translation and application. In the present review, we discuss the most promising candidates for clinical application and the state of the art of their production and supply. In this review, along with 2 forthcoming reviews on chelation and clinical application of α-emitting radionuclides,

© 2021 by the Society of Nuclear Medicine and Molecular Imaging.

Keywords: 211At; 212Pb/212Bi; 225Ac/213Bi; 227Th/223Ra; production and supply of radionuclides; targeted α-therapy

References

  1. N Engl J Med. 2013 Jul 18;369(3):213-23 - PubMed
  2. Sci Rep. 2015 Jul 14;5:12025 - PubMed
  3. Semin Nucl Med. 2020 Mar;50(2):119-123 - PubMed
  4. Nucl Med Biol. 2017 Aug;51:1-9 - PubMed
  5. Sci Rep. 2017 Aug 15;7(1):8216 - PubMed
  6. Appl Radiat Isot. 2005 Mar;62(3):383-7 - PubMed
  7. J Med Imaging Radiat Sci. 2019 Dec;50(4S1):S18-S20 - PubMed
  8. Anal Chem. 2005 Oct 1;77(19):6288-91 - PubMed
  9. Curr Radiopharm. 2018;11(3):156-172 - PubMed
  10. Curr Radiopharm. 2012 Jul;5(3):244-52 - PubMed
  11. Appl Radiat Isot. 2005 May;62(5):667-79 - PubMed
  12. Appl Radiat Isot. 2001 Oct;55(4):433-9 - PubMed
  13. Nucl Med Biol. 2017 May;48:31-35 - PubMed
  14. Eur J Nucl Med Mol Imaging. 2004 Apr;31(4):547-54 - PubMed
  15. EJNMMI Radiopharm Chem. 2017;1(1):5 - PubMed
  16. Target Oncol. 2018 Apr;13(2):189-203 - PubMed
  17. Curr Radiopharm. 2018;11(3):200-208 - PubMed
  18. Pharmaceuticals (Basel). 2014 Mar 13;7(3):353-65 - PubMed
  19. Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):614-622 - PubMed
  20. Appl Radiat Isot. 2017 Jan;119:36-42 - PubMed
  21. Anal Chem. 2008 Nov 15;80(22):8763-70 - PubMed
  22. J Nucl Med. 2018 Jun;59(6):878-884 - PubMed
  23. Sci Rep. 2019 Nov 18;9(1):16960 - PubMed
  24. Appl Radiat Isot. 1996 Feb;47(2):135-43 - PubMed
  25. Cancer Biother Radiopharm. 2013 Feb;28(1):1-20 - PubMed
  26. Curr Radiopharm. 2018;11(3):180-191 - PubMed
  27. Dalton Trans. 2011 Jun 21;40(23):6068-76 - PubMed
  28. Inorg Chem. 2020 Sep 8;59(17):12156-12165 - PubMed
  29. EJNMMI Radiopharm Chem. 2021 Feb 1;6(1):6 - PubMed
  30. Appl Radiat Isot. 2008 Oct;66(10):1275-80 - PubMed
  31. Nucl Med Biol. 2014 May;41 Suppl:e19-22 - PubMed
  32. Phys Med Biol. 2015 Feb 7;60(3):931-46 - PubMed
  33. EJNMMI Radiopharm Chem. 2019 Aug 6;4(1):21 - PubMed
  34. Curr Radiopharm. 2011 Jul;4(3):177-85 - PubMed
  35. Appl Radiat Isot. 2016 Dec;118:366-374 - PubMed
  36. Appl Radiat Isot. 2020 Oct;164:109262 - PubMed

Publication Types