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S Afr Med J. 1978 Mar 25;53(12):433-6.

alpha-Fetoprotein in liver disease.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

M G Alexander, L R Purves, R E Kirsch, N M Bass, N Gitlin, J Terblanche, S J Saunders

PMID: 79225


Ther serum concentration of alpha-fetoprotein (AFP) was measured by radio-immunoassay in 98 patients with liver disease including hepatoma, chronic active hepatitis, alcoholic cirrhosis, and acute virus B hepatitis. Raised AFP levels, above 30 ng/ml, were found in 87% of patients with acute viral hepatitis, in 82% of patients with primary liver cell carcinoma, in 58% with chronic active hepatitis and in 14% of patients with alcoholic cirrhosis. However, levels above 1 000 ng/ml were found only in patients with hepatoma and in acute viral hepatitis.

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