Tell R, Wang QT, Blunier A, Benya RV.
Clin Epigenetics. 2011 Aug;2(2):331-8. doi: 10.1007/s13148-011-0027-5. Epub 2011 Mar 29.
Epithelial cells lining the adult colon do not normally express gastrin-releasing peptide (GRP) or its receptor (GRPR). In contrast, GRP/GRPR can be aberrantly expressed in human colorectal cancer (CRC) including Caco-2 cells. We have previously shown that GRPR activation...
Journal of insect physiology
Wei Z, Baggerman G, J Nachman R, Goldsworthy G, Verhaert P, De Loof A, Schoofs L.
J Insect Physiol. 2000 Sep 01;46(9):1259-1265. doi: 10.1016/s0022-1910(00)00046-9.
In vertebrates, the peptides cholecystokinin (CCK), neuropeptide Y, galanin, and bombesin are known to be involved in the control of food intake. We report here that insect sulfakinins, peptides which display substantial sequence similarities with the vertebrate gastrin/CCK peptide...
Tissue & cell
Falugi C, Davoli C.
Tissue Cell. 1993 Jun;25(3):311-23. doi: 10.1016/0040-8166(93)90073-t.
This histochemical-immunohistochemical study was performed on the earthworm Eisenia foetida at different developmental stages, to investigate the presence and distribution of cholinergic molecules (AChE, BuChE, alpha-bungarotoxin-binding sites), several biogenic amines (5HT and catecholamines), and some immunologically-related peptides (somatostatin. FMRF-amide,...
Pharmacological reports : PR
Gajjar S, Patel BM.
Pharmacol Rep. 2017 May;69(3):438-447. doi: 10.1016/j.pharep.2017.01.009. Epub 2017 Jan 22.
Neuropeptides are small protein used by neurons in signal communications. Neuromedin U was the first neuropeptide discovered from the porcine spinal and showed its potent constricting activities on uterus hence was entitled with neuromedin U. Following neuromedin U another...
Molecular and cellular neurosciences
Lee MC, Jensen RT, Coy DH, Moody TW.
Mol Cell Neurosci. 1990 Oct;1(2):161-7. doi: 10.1016/1044-7431(90)90021-u.
The binding properties and autoradiographic distribution of radiolabeled neuromedin B (NMB) to rat brain sections were investigated. (125)I-NMB bound with high affinity (K(d) = 1 nM) to a single class of sites (B(max) = 80 fmol/mg protein) in coronal...
Dementia & neuropsychologia
Roesler R, Luft T, Schwartsmann G.
Dement Neuropsychol. 2007 Apr-Jun;1(2):118-123. doi: 10.1590/s1980-57642008dn10200002.
Increasing evidence indicates that bombesin (BB)-like peptides (BLPs), such as the gastrin-releasing peptide (GRP) and its receptor (GRPR), might play a role in neurological and psychiatric disorders. The present study reviews findings from animal and human studies suggesting that...
Acta physiologica Scandinavica
Westermark T, Isaksson T, Holmberg P, Kjörell U, Rantapää-Dahlqvist S, Forsgren S.
Acta Physiol Scand. 1999 Oct;167(2):A8. doi: 10.1046/j.1365-201x.1999.0600h.x.
No abstract available.
Fish physiology and biochemistry
Van Noorden S.
Fish Physiol Biochem. 1990 Sep;8(5):399-408. doi: 10.1007/BF00003371.
The current state of knowledge about regulatory peptides in endocrine cells and nerves of the alimentary canal of lampreys and hagfishes is reviewed. Cyclostomes have a wide range of peptides similar immunochemically to those of higher vertebrates. They include,...
Fani M, Maecke HR, Okarvi SM.
Theranostics. 2012;2(5):481-501. doi: 10.7150/thno.4024. Epub 2012 May 16.
Human cancer cells overexpress many peptide receptors as molecular targets. Radiolabeled peptides that bind with high affinity and specificity to the receptors on tumor cells hold great potential for both diagnostic imaging and targeted radionuclide therapy. The advantage of...
International journal of peptides
Wisser AS, Habbel P, Wiedenmann B, Klapp BF, Mönnikes H, Kobelt P.
Int J Pept. 2010;2010. doi: 10.1155/2010/817457. Epub 2010 Jan 06.
Food intake behaviour and energy homeostasis are strongly regulated by a complex system of humoral factors and nerval structures constituting the brain-gut-axis. To date the only known peripherally produced and centrally acting peptide that stimulates food intake is ghrelin,...
Tissue & cell
De Rada OD, Burrell MA, García C, Barrenechea MA, Sesma P.
Tissue Cell. 1992;24(5):705-13. doi: 10.1016/0040-8166(92)90041-5.
The general identification of endocrine cells in the stomach of the lizard Podarcis hispanica was carried out by their response to the Grimelius and Masson-Fontana techniques. 11 immunoreactive cell-types, positive for chromogranin-, serotonin-, caerulein/gastrin/ cholecystokinin (CAER/G/CCK)-, glucagon-like-peptide-1 (GLP-1)-. glucagon-,...
Frontiers in endocrinology
Moody TW, Tashakkori N, Mantey SA, Moreno P, Ramos-Alvarez I, Leopoldo M, Jensen RT.
Front Endocrinol (Lausanne). 2017 Jul 21;8:176. doi: 10.3389/fendo.2017.00176. eCollection 2017.
While peptide antagonists for the gastrin-releasing peptide receptor (BB