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EEC note for guidance: good clinical practice for trials on medicinal products in the European Community. CPMP Working Party on Efficacy of Medicinal Products.

Pharmacology & toxicology

[No authors listed]
PMID: 2077532
Pharmacol Toxicol. 1990 Oct;67(4):361-72. doi: 10.1111/j.1600-0773.1990.tb00847.x.

No abstract available.


Basic & clinical pharmacology & toxicology

[No authors listed]
PMID: 26995454
Basic Clin Pharmacol Toxicol. 2016 Apr;118(4):320. doi: 10.1111/bcpt.12564.

No abstract available.

The grass isn't always greener: The effects of cannabis on embryological development.

BMC pharmacology & toxicology

Friedrich J, Khatib D, Parsa K, Santopietro A, Gallicano GI.
PMID: 27680736
BMC Pharmacol Toxicol. 2016 Sep 29;17(1):45. doi: 10.1186/s40360-016-0085-6.

With the increasing publicity of marijuana due to recent legislation, it is pertinent that the effects of fetal exposure to the drug are assessed. While in utero cannabis exposure has been associated with early pregnancy failure, birth defects and...

Nils-Olof Abdon; 1910-1957.

Acta pharmacologica et toxicologica

PMID: 13508263
Acta Pharmacol Toxicol (Copenh). 1958;14(2):101-3. doi: 10.1111/j.1600-0773.1958.tb01146.x.

No abstract available.

Good clinical practice is now obligatory in academic clinical drug research in the European Union.

Basic & clinical pharmacology & toxicology

Jørgensen A, Bach KF, Friis K.
PMID: 14748847
Basic Clin Pharmacol Toxicol. 2004 Feb;94(2):57-8. doi: 10.1111/j.1742-7843.2004.pto940201.x.

By May 2004, all clinical trials in the European Union (EU) on medicinal products have to be initiated and conducted in compliance with the principles in the new directive on Good Clinical Practice (GCP). This requirement will also apply...

Behavioral, Physiological and Biochemical Hormetic Responses to the Autoxidizable Dye Methylene Blue.

American journal of pharmacology and toxicology

Bruchey AK, Gonzalez-Lima F.
PMID: 20463863
Am J Pharmacol Toxicol. 2008 Jan 01;3(1):72-79. doi: 10.3844/ajptsp.2008.72.79.

The goals of this review were to identify methylene blue (MB) as a compound that follows hormetic behavior for a wide range of effects and to address the question of what is unique about MB that could account for...

The inhibition of Etoposide-induced apoptosis by zinc is associated with modulation of intracellular ph.

International journal of oncology

Morana S, Li J, Springer E, Eastman A.
PMID: 21559569
Int J Oncol. 1994 Aug;5(2):153-8.

Apoptosis is associated with DNA fragmentation, usually as a result of the activation of an endonuclease that digests chromatin DNA between the nucleosomes. The identity of the endonuclease is important for understanding the regulation of apoptosis. A Ca2+/Mg2+-dependent endonuclease...

Abstracts for the XXVII Congress of the Spanish Society for Clinical Pharmacology, 2-4 October 2014, Seville, Spain.

Basic & clinical pharmacology & toxicology

[No authors listed]
PMID: 25273596
Basic Clin Pharmacol Toxicol. 2014 Oct;115:1-51. doi: 10.1111/bcpt.12297.

No abstract available.

CP-25 Alleviates Experimental Sjögren's Syndrome Features in NOD/Ltj Mice and Modulates T Lymphocyte Subsets.

Basic & clinical pharmacology & toxicology

Gu F, Xu S, Zhang P, Chen X, Wu Y, Wang C, Gao M, Si M, Wang X, Heinrich K, Wu H, Wei W.
PMID: 29665238
Basic Clin Pharmacol Toxicol. 2018 Apr 17; doi: 10.1111/bcpt.13025. Epub 2018 Apr 17.

Primary Sjögren's syndrome (pSS) is a chronic inflammatory autoimmune illness of the moisture-producing glands such as salivary glands that is characterized by various immune abnormalities. The aetiology of pSS remains unclear and there is no curative agent. In this...

Effects of UGT1A1, CYP3A5 and ABCB1 Genetic Variants on Pharmacokinetics of Antihistamine Drug Mizolastine in Chinese Healthy Volunteers.

Basic & clinical pharmacology & toxicology

Li P, Wei MJ, Zhang ZY, Yin SJ, Wang X, Lou YQ, Kang ZS, Lu Y, Wei X, Zhai SD, Zhang GL.
PMID: 29702735
Basic Clin Pharmacol Toxicol. 2018 Apr 27; doi: 10.1111/bcpt.13028. Epub 2018 Apr 27.

Mizolastine is a selective histamine H1 receptor antagonist for chronic urticaria or allergic rhinitis. We investigated whether the variant genotypes of metabolic enzymes UGT1A1, CYP3A5 and transporter ABCB1 influence pharmacokinetic phenotype of substrate mizolastine in Chinese volunteers. Genotyping of...

Corrigendum to "A new rat model of neonatal bilirubin encephalopathy (kernicterus)" [J. Pharmacol. Toxicol. Methods 84 (2017) 44-50].

Journal of pharmacological and toxicological methods

Amini N, Vousooghi N, Soleimani M, Samadikuchaksaraei A, Akbari M, Safakheil H, Atafimanesh P, Shahbazi A, Brouki Milan P, Ramezani S, Mozafari M, Joghataei MT.
PMID: 29534860
J Pharmacol Toxicol Methods. 2018 Jul - Aug;92:95. doi: 10.1016/j.vascn.2018.02.006. Epub 2018 Mar 11.

No abstract available.

1st Meeting in Translational Pharmacology, 38th SEF national meeting/9th SEFF meeting 19-20 June 2018, Spain.

Basic & clinical pharmacology & toxicology

[No authors listed]
PMID: 30129096
Basic Clin Pharmacol Toxicol. 2018 Aug;123:3-96. doi: 10.1111/bcpt.13084.

No abstract available.

Showing 1 to 12 of 548 entries