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Showing 13 to 24 of 1983 entries
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The Geometry of Plasticity-Induced Sensitization in Isoinhibitory Rate Motifs.

Neural computation

Kumar G, Ching S.
PMID: 27391684
Neural Comput. 2016 Sep;28(9):1889-926. doi: 10.1162/NECO_a_00865. Epub 2016 Jul 08.

A well-known phenomenon in sensory perception is desensitization, wherein behavioral responses to persistent stimuli become attenuated over time. In this letter, our focus is on studying mechanisms through which desensitization may be mediated at the network level and, specifically,...

Clonal analysis of meningococci during a 26 year period prior to the introduction of meningococcal serogroup C vaccines.

PloS one

Sullivan CB, Diggle MA, Davies RL, Clarke SC.
PMID: 25615448
PLoS One. 2015 Jan 23;10(1):e115741. doi: 10.1371/journal.pone.0115741. eCollection 2015.

Meningococcal disease remains a public health burden in the UK and elsewhere. Invasive Neisseria meningitidis, isolated in Scotland between 1972 and 1998, were characterised retrospectively to examine the serogroup and clonal structure of the circulating population. 2607 isolates causing...

Development and evaluation of a Smartphone-enabled, caregiver-supported educational intervention for management of physical disabilities following stroke in India: protocol for a formative research study.

BMJ innovations

Sureshkumar K, Murthy GV, Kinra S, Goenka S, Kuper H.
PMID: 26751379
BMJ Innov. 2015 Jul;1(3):117-126. doi: 10.1136/bmjinnov-2015-000042.

The incidence and prevalence of stroke in India has reached epidemic proportions. The growing magnitude of disability in patients with stroke in India poses a major public health challenge. Given the nature of the condition, affected individuals often become...

Third-line antiretroviral therapy in Africa: effectiveness in a Southern African retrospective cohort study.

AIDS research and therapy

Meintjes G, Dunn L, Coetsee M, Hislop M, Leisegang R, Regensberg L, Maartens G.
PMID: 26628902
AIDS Res Ther. 2015 Dec 01;12:39. doi: 10.1186/s12981-015-0081-8. eCollection 2015.

BACKGROUND: An increasing number of patients in Africa are experiencing virologic failure on second-line antiretroviral therapy (ART) and those who develop resistance to protease inhibitors (PI) will require third-line ART, but no data on the outcomes of third-line are...

Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria.

Science immunology

Lönnberg T, Svensson V, James KR, Fernandez-Ruiz D, Sebina I, Montandon R, Soon MS, Fogg LG, Nair AS, Liligeto U, Stubbington MJ, Ly LH, Bagger FO, Zwiessele M, Lawrence ND, Souza-Fonseca-Guimaraes F, Bunn PT, Engwerda CR, Heath WR, Billker O, Stegle O, Haque A, Teichmann SA.
PMID: 28345074
Sci Immunol. 2017 Mar 03;2(9). doi: 10.1126/sciimmunol.aal2192.

Differentiation of naïve CD4

Analysis and prediction of defects in UV photo-initiated polymer microarrays.

Journal of materials chemistry. B

Hook AL, Scurr DJ, Burley JC, Langer R, Anderson DG, Davies MC, Alexander MR.
PMID: 25798286
J Mater Chem B. 2013 Feb 21;1(7):1035-1043. doi: 10.1039/c2tb00379a. Epub 2012 Dec 20.

Polymer microarrays are a key enabling technology for the discovery of novel materials. This technology can be further enhanced by expanding the combinatorial space represented on an array. However, not all materials are compatible with the microarray format and...

Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P, Eckardt KU, Kronenberg F, Kleta R, Köttgen A.
PMID: 27333618
Nephrol Dial Transplant. 2017 Feb 01;32(2):325-332. doi: 10.1093/ndt/gfw001. Epub 2016 Feb 04.

BACKGROUND: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants identified MN-associated loci at HLA-DQA1 and PLA2R1.METHODS: We used a combined approach of genotype imputation, GWAS,...

Using fine-scale spatial genetics of Norway rats to improve control efforts and reduce leptospirosis risk in urban slum environments.

Evolutionary applications

Richardson JL, Burak MK, Hernandez C, Shirvell JM, Mariani C, Carvalho-Pereira TS, Pertile AC, Panti-May JA, Pedra GG, Serrano S, Taylor J, Carvalho M, Rodrigues G, Costa F, Childs JE, Ko AI, Caccone A.
PMID: 28352293
Evol Appl. 2017 Feb 23;10(4):323-337. doi: 10.1111/eva.12449. eCollection 2017 Apr.

The Norway rat (

Frontiers in microbiology

Dittmann KK, Chaul LT, Lee SHI, Corassin CH, Fernandes de Oliveira CA, Pereira De Martinis EC, Alves VF, Gram L, Oxaran V.
PMID: 29123505
Front Microbiol. 2017 Oct 24;8:2049. doi: 10.3389/fmicb.2017.02049. eCollection 2017.

No abstract available.

The role of funders: Wellcome Trust.

Public health reviews

Molton S.
PMID: 29450050
Public Health Rev. 2016 Aug 24;37:8. doi: 10.1186/s40985-016-0022-7. eCollection 2016.

Wellcome exists to improve health for everyone by helping great ideas to thrive. We are a global charitable foundation, both politically and financially independent. We support scientists and researchers take on big problems, fuel imaginations and spark debate. The...

Direct Adherence Measurement Using an Ingestible Sensor Compared With Self-Reporting in High-Risk Cardiovascular Disease Patients Who Knew They Were Being Measured: A Prospective Intervention.

JMIR mHealth and uHealth

Thompson D, Mackay T, Matthews M, Edwards J, Peters NS, Connolly SB.
PMID: 28606895
JMIR Mhealth Uhealth. 2017 Jun 12;5(6):e76. doi: 10.2196/mhealth.6998.

BACKGROUND: Use of appropriate cardioprotective medication is a cornerstone of cardiovascular disease prevention, but less-than-optimal patient adherence is common. Thus, strategies for improving adherence are recommended to adopt a multifaceted approach.OBJECTIVE: The objective of our study was to test...

Carbon Nanotube Array Based Binary Gabor Zone Plate Lenses.

Scientific reports

Deng S, Jwad T, Li C, Benton D, Yetisen AK, Jiang K, Dai Q, Butt H.
PMID: 29127317
Sci Rep. 2017 Nov 10;7(1):15256. doi: 10.1038/s41598-017-15472-9.

Diffractive zone plates have a wide range of applications from focusing x-ray to extreme UV radiation. The Gabor zone plate, which suppresses the higher-order foci to a pair of conjugate foci, is an attractive alternative to the conventional Fresnel...

Showing 13 to 24 of 1983 entries