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Showing 25 to 36 of 173 entries
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Rationale for Targeting Deregulated Metabolic Pathways as a Therapeutic Strategy in Acute Myeloid Leukemia.

Frontiers in oncology

Chapuis N, Poulain L, Birsen R, Tamburini J, Bouscary D.
PMID: 31192118
Front Oncol. 2019 May 22;9:405. doi: 10.3389/fonc.2019.00405. eCollection 2019.

Metabolic reprogramming is a common cancer cell phenotype as it sustains growth and proliferation. Targeting metabolic activities offers a wide range of therapeutic possibilities which are applicable to acute myeloid leukemia (AML). Indeed, in addition to the IDH1/2-mutated AML...

Erratum to: Predictors of Perianal Fistula Relapse in Crohn's Disease.

Inflammatory bowel diseases

Malian A, Rivière P, Bouchard D, Pigot F, Eléouet-Kaplan M, Favreau-Weltzer C, Poullenot F, Laharie D.
PMID: 33277906
Inflamm Bowel Dis. 2021 Jul 27;27(8):1365. doi: 10.1093/ibd/izaa272.

No abstract available.

Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia.

Oncogenesis

Meunier G, Birsen R, Cazelles C, Belhadj M, Cantero-Aguilar L, Kosmider O, Fontenay M, Azar N, Mayeux P, Chapuis N, Tamburini J, Bouscary D.
PMID: 33093450
Oncogenesis. 2020 Oct 22;9(10):94. doi: 10.1038/s41389-020-00278-8.

Acute myeloid leukemia (AML) is an aggressive disease with a poor prognosis. Vacuolar protein sorting 34 (VPS34) is a member of the phosphatidylinositol-3-kinase lipid kinase family that controls the canonical autophagy pathway and vesicular trafficking. Using a recently developed...

Head and neck skin expansion: assessment of efficiency for the treatment of lesions in the lower half of the face.

Annals of burns and fire disasters

Sabban R, Serror K, Levy J, Chaouat M, Mimoun M, Boccara D.
PMID: 32523494
Ann Burns Fire Disasters. 2020 Mar 31;33(1):38-46.

The treatment of sequelae for burns or other loss of perioral tissues is complex due to the site where they occur, its functional importance, and social and esthetic aspects. Functional consequences of burns to this area are cutaneous retraction...

Burns Caused by Exploding Standing Electric Scooters (E-Scooters): A New Phenomenon.

Journal of burn care & research : official publication of the American Burn Association

Ragonez D, Mimoun M, Chaouat M, Levy S, Vairinho A, Boccara D, Serror K.
PMID: 33156906
J Burn Care Res. 2021 Mar 04;42(2):348-349. doi: 10.1093/jbcr/iraa201.

No abstract available.

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed. Part 1: .

EFSA journal. European Food Safety Authority

, Koutsoumanis K, Allende A, Alvarez-Ordóñez A, Bolton D, Bover-Cid S, Chemaly M, Davies R, De Cesare A, Herman L, Hilbert F, Lindqvist R, Nauta M, Ru G, Simmons M, Skandamis P, Suffredini E, Andersson DI, Bampidis V, Bengtsson-Palme J, Bouchard D, Ferran A, Kouba M, López Puente S, López-Alonso M, Nielsen SS, Pechová A, Petkova M, Girault S, Broglia A, Guerra B, Innocenti ML, Liébana E, López-Gálvez G, Manini P, Stella P, Peixe L.
PMID: 34729081
EFSA J. 2021 Oct 26;19(10):e06852. doi: 10.2903/j.efsa.2021.6852. eCollection 2021 Oct.

The European Commission requested EFSA to assess, in collaboration with EMA, the specific concentrations of antimicrobials resulting from cross-contamination in non-target feed for food-producing animals below which there would not be an effect on the emergence of, and/or selection...

Maximum levels of cross-contamination for 24 antimicrobial active substances in non-target feed.
Part 2: .

EFSA journal. European Food Safety Authority

, Allende A, Koutsoumanis K, Allende A, Alvarez-Ordóñez A, Bolton D, Bover-Cid S, Chemaly M, Davies R, De Cesare A, Herman L, Hilbert F, Lindqvist R, Nauta M, Ru G, Simmons M, Skandamis P, Suffredini E, Andersson DI, Bampidis V, Bengtsson-Palme J, Bouchard D, Ferran A, Kouba M, López Puente S, López-Alonso M, Nielsen SS, Pechová A, Petkova M, Girault S, Broglia A, Guerra B, Innocenti ML, Liébana E, López-Gálvez G, Manini P, Stella P, Peixe L.
PMID: 34729082
EFSA J. 2021 Oct 26;19(10):e06853. doi: 10.2903/j.efsa.2021.6853. eCollection 2021 Oct.

The specific concentrations of apramycin, paromomycin, neomycin and spectinomycin in non-target feed for food-producing animals, below which there would not be an effect on the emergence of, and/or selection for, resistance in bacteria relevant for human and animal health,...

Environmental contamination in a high-income country (France) by antibiotics, antibiotic-resistant bacteria, and antibiotic resistance genes: Status and possible causes.

Environment international

Haenni M, Dagot C, Chesneau O, Bibbal D, Labanowski J, Vialette M, Bouchard D, Martin-Laurent F, Calsat L, Nazaret S, Petit F, Pourcher AM, Togola A, Bachelot M, Topp E, Hocquet D.
PMID: 34923370
Environ Int. 2021 Dec 16;159:107047. doi: 10.1016/j.envint.2021.107047. Epub 2021 Dec 16.

Antimicrobial resistance (AMR) is a major global public health concern, shared by a large number of human and animal health actors. Within the framework of a One Health approach, actions should be implemented in the environmental realm, as well...

Antimetabolic cooperativity with the clinically approved l-asparaginase and tyrosine kinase inhibitors to eradicate CML stem cells.

Molecular metabolism

Trinh A, Khamari R, Fovez Q, Mahon FX, Turcq B, Bouscary D, Maboudou P, Joncquel M, Coiteux V, Germain N, Laine W, Dekiouk S, Jean-Pierre S, Maguer-Satta V, Ghesquiere B, Idziorek T, Quesnel B, Kluza J, Marchetti P.
PMID: 34863941
Mol Metab. 2021 Dec 01;55:101410. doi: 10.1016/j.molmet.2021.101410. Epub 2021 Dec 01.

OBJECTIVE: Long-term treatment with tyrosine kinase inhibitors (TKI) represents an effective cure for chronic myeloid leukemia (CML) patients and discontinuation of TKI therapy is now proposed to patient with deep molecular responses. However, evidence demonstrating that TKI are unable...

ANTIMETABOLIC COOPERATIVITY WITH THE CLINICALLY-APPROVED L-ASPARAGINASE AND TYROSINE KINASE INHIBITORS TO ERADICATE CML STEM CELLS.

Molecular metabolism

Trinh A, Khamari R, Fovez Q, Mahon FX, Turcq B, Bouscary D, Maboudou P, Joncquel M, Coiteux V, Germain N, Laine W, Dekiouk S, Jean-Pierre S, Maguer-Satta V, Ghesquiere B, Idziorek T, Quesnel B, Kluza J, Marchetti P.
PMID: 34863941
Mol Metab. 2021 Dec 01;101410. doi: 10.1016/j.molmet.2021.101410. Epub 2021 Dec 01.

Long-term treatment with tyrosine kinase inhibitors (TKI) represents an effective treatment for chronic myeloid leukemia (CML) and discontinuation of TKI therapy is now being proposed to patients with deep molecular responses. However, evidence demonstrating that TKI are unable to...

Nature of phase transitions in a probabilistic cellular automaton with two absorbing states.

Physical review. E, Statistical, nonlinear, and soft matter physics

Bagnoli F, Boccara N, Rechtman R.
PMID: 11308921
Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Apr;63(4):046116. doi: 10.1103/PhysRevE.63.046116. Epub 2001 Mar 29.

We present a probabilistic cellular automaton with two absorbing states, which can be considered a natural extension of the Domany-Kinzel model. Despite its simplicity, it shows a very rich phase diagram, with two second-order and one first-order transition lines...

Nanotectonic approach of the texturation of CeO2 based nanomaterials.

Chemical communications (Cambridge, England)

Bouchara A, Soler-Illia GJ, Chane-Ching JY, Sanchez C.
PMID: 12109098
Chem Commun (Camb). 2002 Jun 07;(11):1234-5. doi: 10.1039/b202316b.

Original and homogeneous macrotextures shaped with coral-like, helical or macroporous sieves morphologies are obtained following a nanotectonic approach based on the template-directed assembly by poly-gamma-benzyl-L-glutamate (PBLG) of organically functionalised CeO2 crystalline nanoparticles.

Showing 25 to 36 of 173 entries