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A case of a speech impediment following a near lightning strike.

International journal of emergency medicine

Desai BK, Fairclough R.
PMID: 21929820
Int J Emerg Med. 2011 Sep 19;4:60. doi: 10.1186/1865-1380-4-60.

Environmental electrical injuries (electrical burns and lightning) are relatively common and are estimated to result in more than 3,000 admissions to specialized burn units each year here in the US. Lightning injuries are a small subset of electrical injuries...

Young inversion with multiple linked QTLs under selection in a hybrid zone.

Nature ecology & evolution

Lee CR, Wang B, Mojica JP, Mandáková T, Prasad KVSK, Goicoechea JL, Perera N, Hellsten U, Hundley HN, Johnson J, Grimwood J, Barry K, Fairclough S, Jenkins JW, Yu Y, Kudrna D, Zhang J, Talag J, Golser W, Ghattas K, Schranz ME, Wing R, Lysak MA, Schmutz J, Rokhsar DS, Mitchell-Olds T.
PMID: 28812690
Nat Ecol Evol. 2017 Apr 03;1(5):119. doi: 10.1038/s41559-017-0119.

Fixed chromosomal inversions can reduce gene flow and promote speciation in two ways: by suppressing recombination and by carrying locally favoured alleles at multiple loci. However, it is unknown whether favoured mutations slowly accumulate on older inversions or if...

School-based interventions modestly increase physical activity and cardiorespiratory fitness but are least effective for youth who need them most: an individual participant pooled analysis of 20 controlled trials.

British journal of sports medicine

Hartwig TB, Sanders T, Vasconcellos D, Noetel M, Parker PD, Lubans DR, Andrade S, Ávila-García M, Bartholomew J, Belton S, Brooks NE, Bugge A, Cavero-Redondo I, Christiansen LB, Cohen K, Coppinger T, Dyrstad S, Errisuriz V, Fairclough S, Gorely T, Javier Huertas-Delgado F, Issartel J, Kriemler S, Kvalø SE, Marques-Vidal P, Martinez-Vizcaino V, Møller NC, Moran C, Morris J, Nevill M, Ochoa-Avilés A, O'Leary M, Peralta L, Pfeiffer KA, Puder J, Redondo-Tébar A, Robbins LB, Sanchez-Lopez M, Tarp J, Taylor S, Tercedor P, Toftager M, Villa-González E, Wedderkopp N, Weston KL, Yin Z, Zhixiong Z, Lonsdale C, Del Pozo Cruz B.
PMID: 33441332
Br J Sports Med. 2021 Jan 13; doi: 10.1136/bjsports-2020-102740. Epub 2021 Jan 13.

OBJECTIVES: To determine if subpopulations of students benefit equally from school-based physical activity interventions in terms of cardiorespiratory fitness and physical activity. To examine if physical activity intensity mediates improvements in cardiorespiratory fitness.DESIGN: Pooled analysis of individual participant data...

Physical activity levels in middle and high school physical education: a review

education interventions

Fairclough S, Stratton G.
GSID: Zn3JJdSm0f4J
S Fairclough, G Stratton - Pediatric exercise science, 2005 - journals.humankinetics.com

Forty studies reporting physical activity during middle and high school physical education (PE) classes were reviewed. Students engaged in moderate-to-vigorous physical activity …

Constitutional de novo deletion CNV encompassing .

Journal of medical genetics

Hyder Z, Fairclough A, Groom M, Getty J, Alexander E, van Veen EM, Makin G, Sethuraman C, Tang V, Evans DG, Maher ER, Woodward ER.
PMID: 32917767
J Med Genet. 2021 Sep;58(9):581-585. doi: 10.1136/jmedgenet-2020-107087. Epub 2020 Sep 11.

BACKGROUND: Nephroblastomatosis is a recognised precursor for the development of Wilms tumour (WT), the most common childhood renal tumour. While the majority of WT is sporadic in origin, germline intragenic mutations of predisposition genes such as OBJECTIVE: To highlight...

Measuring the Impact of Physical Activity Interventions in Young People

after-school interventions

Fairclough S.
GSID: 158nwP7iEusJ
S Fairclough - researchgate.net

… • Majority of staff time spent on afterschool/summer programme – this prevented full implementation of other components … • Physical activity interventions that use ecological approaches are more likely to make an impact than those which use a...

Personalised virtual gene panels reduce interpretation workload and maintain diagnostic rates of proband-only clinical exome sequencing for rare disorders.

Journal of medical genetics

Molina-Ramírez LP, Kyle C, Ellingford JM, Wright R, Taylor A, Bhaskar SS, Campbell C, Jackson H, Fairclough A, Rousseau A, Burghel GJ, Dutton L, Banka S, Briggs TA, Clayton-Smith J, Douzgou S, Jones EA, Kingston HM, Kerr B, Ealing J, Somarathi S, Chandler KE, Stuart HM, Burkitt-Wright EM, Newman WG, Bruce IA, Black GC, Gokhale D.
PMID: 33879512
J Med Genet. 2021 Apr 20; doi: 10.1136/jmedgenet-2020-107303. Epub 2021 Apr 20.

PURPOSE: The increased adoption of genomic strategies in the clinic makes it imperative for diagnostic laboratories to improve the efficiency of variant interpretation. Clinical exome sequencing (CES) is becoming a valuable diagnostic tool, capable of meeting the diagnostic demand...

Soluble TIM3 and Its Ligands Galectin-9 and CEACAM1 Are in Disequilibrium During Alcohol-Related Liver Disease and Promote Impairment of Anti-bacterial Immunity.

Frontiers in physiology

Riva A, Palma E, Devshi D, Corrigall D, Adams H, Heaton N, Menon K, Preziosi M, Zamalloa A, Miquel R, Ryan JM, Wright G, Fairclough S, Evans A, Shawcross D, Schierwagen R, Klein S, Uschner FE, Praktiknjo M, Katzarov K, Hadzhiolova T, Pavlova S, Simonova M, Trebicka J, Williams R, Chokshi S.
PMID: 33776793
Front Physiol. 2021 Mar 10;12:632502. doi: 10.3389/fphys.2021.632502. eCollection 2021.

BACKGROUND AND AIMS: Immunoregulatory checkpoint receptors (CR) contribute to the profound immunoparesis observed in alcohol-related liver disease (ALD) and METHODS: In Alcoholic Hepatitis (AH; RESULTS: Soluble-TIM3 was the dominant plasma soluble-CR in ALD vs. HC (CONCLUSIONS: Alcohol-related liver disease...

Editorial: Post-translational Modifications in Plant Nuclear Signaling: Novel Insights Into Responses to Environmental Changes.

Frontiers in plant science

Bourque S, Lindermayr C, Mazars C, Fairclough N.
PMID: 30804971
Front Plant Sci. 2019 Feb 11;10:104. doi: 10.3389/fpls.2019.00104. eCollection 2019.

No abstract available.

Acquired Resistance to Poly (ADP-ribose) Polymerase Inhibitor Olaparib in .

JCO precision oncology

Carneiro BA, Collier KA, Nagy RJ, Pamarthy S, Sagar V, Fairclough S, Odegaard J, Lanman RB, Costa R, Taxter T, Kuzel TM, Fan A, Chae YK, Cristofanilli M, Hussain MH, Abdulkadir SA, Giles FJ, Crawford R, Jenkins L.
PMID: 31501807
JCO Precis Oncol. 2018;2. doi: 10.1200/PO.17.00176. Epub 2018 Feb 14.

PARP1/2 inhibitors are effective against BRCA2-deficient tumors. The PARP inhibitor (PARPi) olaparib received FDA breakthrough designation for treatment of metastatic castration-resistant prostate cancers (CRPC) carrying mutations in

Exploring the Perceived Usefulness and Ease of Use of a Personalized Web-Based Resource (Care Companion) to Support Informal Caring: Qualitative Descriptive Study.

JMIR aging

Turk A, Fairclough E, Grason Smith G, Lond B, Nanton V, Dale J.
PMID: 31518272
JMIR Aging. 2019 Aug 20;2(2):e13875. doi: 10.2196/13875.

BACKGROUND: Informal carers play an increasingly vital role in supporting the older population and the sustainability of health care systems. Care Companion is a theory-based and coproduced Web-based intervention to help support informal carers' resilience. It aims to provide...

Editorial: High Performance Cognition: Information-Processing in Complex Skills, Expert Performance, and Flow.

Frontiers in psychology

Cowley BU, Dehais F, Fairclough S, Karran AJ, Palomäki J, Lappi O.
PMID: 33123061
Front Psychol. 2020 Oct 06;11:579950. doi: 10.3389/fpsyg.2020.579950. eCollection 2020.

No abstract available.

Showing 1 to 12 of 125 entries