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Showing 1 to 12 of 7258 entries
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A combination of intradermal jet-injection and electroporation overcomes in vivo dose restriction of DNA vaccines.

Genetic vaccines and therapy

Hallengärd D, Bråve A, Isaguliants M, Blomberg P, Enger J, Stout R, King A, Wahren B.
PMID: 22873174
Genet Vaccines Ther. 2012 Aug 08;10(1):5. doi: 10.1186/1479-0556-10-5.

BACKGROUND: The use of optimized delivery devices has been shown to enhance the potency of DNA vaccines. However, further optimization of DNA vaccine delivery is needed for this vaccine modality to ultimately be efficacious in humans.METHODS: Herein we evaluated...

A facile route for 3D aerogels from nanostructured 1D and 2D materials.

Scientific reports

Jung SM, Jung HY, Dresselhaus MS, Jung YJ, Kong J.
PMID: 23152940
Sci Rep. 2012;2:849. doi: 10.1038/srep00849. Epub 2012 Nov 14.

Aerogels have numerous applications due to their high surface area and low densities. However, creating aerogels from a large variety of materials has remained an outstanding challenge. Here, we report a new methodology to enable aerogel production with a...

Synthesis, field-emission and electric properties of metastable phase VO2 (A) ultra-long nanobelts.

Dalton transactions (Cambridge, England : 2003)

Li M, Kong F, Li L, Zhang Y, Chen L, Yan W, Li G.
PMID: 21918759
Dalton Trans. 2011 Nov 07;40(41):10961-5. doi: 10.1039/c1dt10941c. Epub 2011 Sep 14.

High quality single crystalline metastable phase VO(2) (A) ultra-long nanobelts were synthesized by hydrothermal method using inorganic V(2)O(5) sol as precursor and polyethylene glycol (PEG) as both surfactant and reducing agent. It was found that the oriented attach growth...

Role of CXC chemokine receptor type 7 in carcinogenesis and lymph node metastasis of colon cancer.

Molecular and clinical oncology

Wang HX, Tao LY, Qi KE, Zhang HY, Feng D, Wei WJ, Kong H, Chen TW, Lin QS, Chen DJ.
PMID: 26807225
Mol Clin Oncol. 2015 Nov;3(6):1229-1232. doi: 10.3892/mco.2015.643. Epub 2015 Sep 15.

Upregulated expression of the CXC chemokine receptor type 7 (CXCR7) promotes breast, lung and prostate cancer progression and metastasis. However, the role of CXCR7 in colon cancer has not been determined. We hypothesized that increased CXCR7 expression may contribute...

Predictive single nucleotide polymorphism markers for acute oral mucositis in patients with nasopharyngeal carcinoma treated with radiotherapy.

Oncotarget

Le Z, Niu X, Chen Y, Ou X, Zhao G, Liu Q, Tu W, Hu C, Kong L, Liu Y.
PMID: 28968968
Oncotarget. 2017 Jun 13;8(38):63026-63037. doi: 10.18632/oncotarget.18450. eCollection 2017 Sep 08.

The aim of this study was to investigate the association between the susceptibility of severe oral mucositis (OM) in Chinese nasopharyngeal carcinoma (NPC) patients treated with radiotherapy and single nucleotide polymorphisms (SNPs) across the whole genome. SNPs were screened...

Asymmetric Hydrogenation of β-Aryloxy/Alkoxy Cinnamic Nitriles and Esters.

Organic letters

Kong D, Li M, Wang R, Zi G, Hou G.
PMID: 27626807
Org Lett. 2016 Oct 07;18(19):4916-4919. doi: 10.1021/acs.orglett.6b02393. Epub 2016 Sep 14.

A highly efficient and enantioselective hydrogenation of β-aryloxy/alkoxy cinnamic nitriles and esters under mild conditions has been realized by using a rhodium catalyst with a chiral f-spiroPhos ligand. The method provides efficient access to the asymmetric synthesis of a...

LIVER WHOLE SLIDE IMAGE ANALYSIS FOR 3D VESSEL RECONSTRUCTION.

Proceedings. IEEE International Symposium on Biomedical Imaging

Liang Y, Wang F, Treanor D, Magee D, Teodoro G, Zhu Y, Kong J.
PMID: 26405504
Proc IEEE Int Symp Biomed Imaging. 2015 Apr;2015:182-185. doi: 10.1109/ISBI.2015.7163845.

The emergence of digital pathology has enabled numerous quantitative analyses of histopathology structures. However, most pathology image analyses are limited to two-dimensional datasets, resulting in substantial information loss and incomplete interpretation. To address this, we have developed a complete...

Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1.

Cell discovery

Lin Z, Tan C, Qiu Q, Kong S, Yang H, Zhao F, Liu Z, Li J, Kong Q, Gao B, Barrett T, Yang GY, Zhang J, Fang D.
PMID: 27030811
Cell Discov. 2015;1. doi: 10.1038/celldisc.2015.28. Epub 2015 Oct 13.

The elevated level of CCNB1 indicates more aggressive cancer and poor prognosis. However, the factors that cause CCNB1 upregulation remain enigmatic. Herein, we identify USP22 as a CCNB1 interactor and discover that both USP22 and CCNB1 are dramatically elevated...

Solution-Liquid-Solid Synthesis, Properties, and Applications of One-Dimensional Colloidal Semiconductor Nanorods and Nanowires.

Chemical reviews

Wang F, Dong A, Buhro WE.
PMID: 26974736
Chem Rev. 2016 Sep 28;116(18):10888-933. doi: 10.1021/acs.chemrev.5b00701. Epub 2016 Mar 14.

The solution-liquid-solid (SLS) and related solution-based methods for the synthesis of semiconductor nanowires and nanorods are reviewed. Since its discovery in 1995, the SLS mechanism and its close variants have provided a nearly general strategy for the growth of...

Elevated Circulating hsa-miR-106b, hsa-miR-26a, and hsa-miR-29b in Type 2 Diabetes Mellitus with Diarrhea-Predominant Irritable Bowel Syndrome.

Gastroenterology research and practice

Tao W, Dong X, Kong G, Fang P, Huang X, Bo P.
PMID: 27635130
Gastroenterol Res Pract. 2016;2016:9256209. doi: 10.1155/2016/9256209. Epub 2016 Aug 22.

Background and Aims. Although the differential expression of microRNA (miRNA) genes has been identified in many diseases, little information exists concerning the miRNA expression profile in type 2 diabetes mellitus (T2DM) with diarrhea-predominant irritable bowel syndrome (D-IBS). Therefore, the...

Bipolar II disorder as the initial presentation of CADASIL: an underdiagnosed manifestation.

Neuropsychiatric disease and treatment

Wang J, Li J, Kong F, Lv H, Guo Z.
PMID: 28860774
Neuropsychiatr Dis Treat. 2017 Aug 14;13:2175-2179. doi: 10.2147/NDT.S142321. eCollection 2017.

Mood disturbances have been documented in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). The highly varied morbidity indicates that the affective symptoms in CADASIL have not been cataloged systematically, leading to ineffective treatment, affecting the patients'...

External Magnetic Field-Enhanced Chemo-Photothermal Combination Tumor Therapy via Iron Oxide Nanoparticles.

ACS applied materials & interfaces

Guo X, Li W, Luo L, Wang Z, Li Q, Kong F, Zhang H, Yang J, Zhu C, Du Y, You J.
PMID: 28453245
ACS Appl Mater Interfaces. 2017 May 17;9(19):16581-16593. doi: 10.1021/acsami.6b16513. Epub 2017 May 03.

The development of multifunctional nanoplatforms based on magnetic nanoparticles (MNPs) has attracted increasing attention. MNPs especially exhibit excellent responsiveness under the guidance of an external magnetic field (MF), resulting in tumor-specific, targeted delivery. The behavior and magnetic-targeting efficiency of...

Showing 1 to 12 of 7258 entries