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Computational design of proteins targeting the conserved stem region of influenza hemagglutinin

STEM and diversification

Fleishman SJ, Whitehead TA.
GSID: bYOKKzyGg6sJ
SJ Fleishman, TA Whitehead, DC Ekiert, C Dreyfus… - Science, 2011 - science.org

… Broadly neutralizing antibody CR6261 binds a highly conserved epitope in the stem region (… to the stem region. Each scaffold protein was docked against the stem region using the …

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Fleishman, S. J., Whitehead, T. A., Ekiert, D. C., Dreyfus, C., Corn, J. E., Strauch, E. M., ... & Baker, D. (2011). Computational design of proteins targeting the conserved stem region of influenza hemagglutinin. Science, 332(6031), 816-821.
Fleishman, Sarel J., et al. "Computational design of proteins targeting the conserved stem region of influenza hemagglutinin." Science 332.6031 (2011): 816-821.
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Ion-scale secondary flux ropes generated by magnetopause reconnection as resolved by MMS.

Geophysical research letters

Eastwood JP, Phan TD, Cassak PA, Gershman DJ, Haggerty C, Malakit K, Shay MA, Mistry R, Øieroset M, Russell CT, Slavin JA, Argall MR, Avanov LA, Burch JL, Chen LJ, Dorelli JC, Ergun RE, Giles BL, Khotyaintsev Y, Lavraud B, Lindqvist PA, Moore TE, Nakamura R, Paterson W, Pollock C, Strangeway RJ, Torbert RB, Wang S.
PMID: 27635105
Geophys Res Lett. 2016 May 28;43(10):4716-4724. doi: 10.1002/2016GL068747. Epub 2016 May 18.

New Magnetospheric Multiscale (MMS) observations of small-scale (~7 ion inertial length radius) flux transfer events (FTEs) at the dayside magnetopause are reported. The 10 km MMS tetrahedron size enables their structure and properties to be calculated using a variety...

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Eastwood JP, Phan TD, Cassak PA, et al. Ion-scale secondary flux ropes generated by magnetopause reconnection as resolved by MMS. Geophys Res Lett. 2016;43(10):4716-4724doi: 10.1002/2016GL068747.
Eastwood, J. P., Phan, T. D., Cassak, P. A., Gershman, D. J., Haggerty, C., Malakit, K., Shay, M. A., Mistry, R., Øieroset, M., Russell, C. T., Slavin, J. A., Argall, M. R., Avanov, L. A., Burch, J. L., Chen, L. J., Dorelli, J. C., Ergun, R. E., Giles, B. L., Khotyaintsev, Y., Lavraud, B., Lindqvist, P. A., Moore, T. E., Nakamura, R., Paterson, W., Pollock, C., Strangeway, R. J., Torbert, R. B., & Wang, S. (2016). Ion-scale secondary flux ropes generated by magnetopause reconnection as resolved by MMS. Geophysical research letters, 43(10), 4716-4724. https://doi.org/10.1002/2016GL068747
Eastwood, J P, et al. "Ion-scale secondary flux ropes generated by magnetopause reconnection as resolved by MMS." Geophysical research letters vol. 43,10 (2016): 4716-4724. doi: https://doi.org/10.1002/2016GL068747
Eastwood JP, Phan TD, Cassak PA, Gershman DJ, Haggerty C, Malakit K, Shay MA, Mistry R, Øieroset M, Russell CT, Slavin JA, Argall MR, Avanov LA, Burch JL, Chen LJ, Dorelli JC, Ergun RE, Giles BL, Khotyaintsev Y, Lavraud B, Lindqvist PA, Moore TE, Nakamura R, Paterson W, Pollock C, Strangeway RJ, Torbert RB, Wang S. Ion-scale secondary flux ropes generated by magnetopause reconnection as resolved by MMS. Geophys Res Lett. 2016 May 28;43(10):4716-4724. doi: 10.1002/2016GL068747. Epub 2016 May 18. PMID: 27635105; PMCID: PMC5001194.
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Wave-particle energy exchange directly observed in a kinetic Alfvén-branch wave.

Nature communications

Gershman DJ, F-Viñas A, Dorelli JC, Boardsen SA, Avanov LA, Bellan PM, Schwartz SJ, Lavraud B, Coffey VN, Chandler MO, Saito Y, Paterson WR, Fuselier SA, Ergun RE, Strangeway RJ, Russell CT, Giles BL, Pollock CJ, Torbert RB, Burch JL.
PMID: 28361881
Nat Commun. 2017 Mar 31;8:14719. doi: 10.1038/ncomms14719.

Alfvén waves are fundamental plasma wave modes that permeate the universe. At small kinetic scales, they provide a critical mechanism for the transfer of energy between electromagnetic fields and charged particles. These waves are important not only in planetary...

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Gershman DJ, F-Viñas A, Dorelli JC, et al. Wave-particle energy exchange directly observed in a kinetic Alfvén-branch wave. Nat Commun. 2017;8:14719doi: 10.1038/ncomms14719.
Gershman, D. J., F-Viñas, A., Dorelli, J. C., Boardsen, S. A., Avanov, L. A., Bellan, P. M., Schwartz, S. J., Lavraud, B., Coffey, V. N., Chandler, M. O., Saito, Y., Paterson, W. R., Fuselier, S. A., Ergun, R. E., Strangeway, R. J., Russell, C. T., Giles, B. L., Pollock, C. J., Torbert, R. B., & Burch, J. L. (2017). Wave-particle energy exchange directly observed in a kinetic Alfvén-branch wave. Nature communications, 814719. https://doi.org/10.1038/ncomms14719
Gershman, Daniel J, et al. "Wave-particle energy exchange directly observed in a kinetic Alfvén-branch wave." Nature communications vol. 8 (2017): 14719. doi: https://doi.org/10.1038/ncomms14719
Gershman DJ, F-Viñas A, Dorelli JC, Boardsen SA, Avanov LA, Bellan PM, Schwartz SJ, Lavraud B, Coffey VN, Chandler MO, Saito Y, Paterson WR, Fuselier SA, Ergun RE, Strangeway RJ, Russell CT, Giles BL, Pollock CJ, Torbert RB, Burch JL. Wave-particle energy exchange directly observed in a kinetic Alfvén-branch wave. Nat Commun. 2017 Mar 31;8:14719. doi: 10.1038/ncomms14719. PMID: 28361881; PMCID: PMC5380972.
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Residual fistula of fourth branchial arch anomalies and recurrent left-side cervical abscess: clinical case and review of the literature.

Case reports in otolaryngology

Hallak B, Bouayed S, Leishman C, Sandu K.
PMID: 25506454
Case Rep Otolaryngol. 2014;2014:931279. doi: 10.1155/2014/931279. Epub 2014 Nov 24.

Congenital fourth branchial arch anomalies are uncommon entities. Most of these anomalies are diagnosed in childhood. The majority of cases occur on the left side. The clinical presentation of these anomalies varies with age. A respiratory distress is the...

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Hallak B, Bouayed S, Leishman C, et al. Residual fistula of fourth branchial arch anomalies and recurrent left-side cervical abscess: clinical case and review of the literature. Case Rep Otolaryngol. 2014;2014:931279doi: 10.1155/2014/931279.
Hallak, B., Bouayed, S., Leishman, C., & Sandu, K. (2014). Residual fistula of fourth branchial arch anomalies and recurrent left-side cervical abscess: clinical case and review of the literature. Case reports in otolaryngology, 2014931279. https://doi.org/10.1155/2014/931279
Hallak, Bassel, et al. "Residual fistula of fourth branchial arch anomalies and recurrent left-side cervical abscess: clinical case and review of the literature." Case reports in otolaryngology vol. 2014 (2014): 931279. doi: https://doi.org/10.1155/2014/931279
Hallak B, Bouayed S, Leishman C, Sandu K. Residual fistula of fourth branchial arch anomalies and recurrent left-side cervical abscess: clinical case and review of the literature. Case Rep Otolaryngol. 2014;2014:931279. doi: 10.1155/2014/931279. Epub 2014 Nov 24. PMID: 25506454; PMCID: PMC4259132.
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Corrigendum: Three keys to the radiation of angiosperms into freezing environments.

Nature

Zanne AE, Tank DC, Cornwell WK, Eastman JM, Smith SA, FitzJohn RG, McGlinn DJ, O'Meara BC, Moles AT, Reich PB, Royer DL, Soltis DE, Stevens PF, Westoby M, Wright IJ, Aarssen L, Bertin RI, Calaminus A, Govaerts R, Hemmings F, Leishman MR, Oleksyn J, Soltis PS, Swenson NG, Warman L, Beaulieu JM.
PMID: 25993966
Nature. 2015 May 21;521(7552):380. doi: 10.1038/nature14371.

No abstract available.

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Zanne AE, Tank DC, Cornwell WK, et al. Corrigendum: Three keys to the radiation of angiosperms into freezing environments. Nature. 2015;521(7552):380doi: 10.1038/nature14371.
Zanne, A. E., Tank, D. C., Cornwell, W. K., Eastman, J. M., Smith, S. A., FitzJohn, R. G., McGlinn, D. J., O'Meara, B. C., Moles, A. T., Reich, P. B., Royer, D. L., Soltis, D. E., Stevens, P. F., Westoby, M., Wright, I. J., Aarssen, L., Bertin, R. I., Calaminus, A., Govaerts, R., Hemmings, F., Leishman, M. R., Oleksyn, J., Soltis, P. S., Swenson, N. G., Warman, L., & Beaulieu, J. M. (2015). Corrigendum: Three keys to the radiation of angiosperms into freezing environments. Nature, 521(7552), 380. https://doi.org/10.1038/nature14371
Zanne, Amy E, et al. "Corrigendum: Three keys to the radiation of angiosperms into freezing environments." Nature vol. 521,7552 (2015): 380. doi: https://doi.org/10.1038/nature14371
Zanne AE, Tank DC, Cornwell WK, Eastman JM, Smith SA, FitzJohn RG, McGlinn DJ, O'Meara BC, Moles AT, Reich PB, Royer DL, Soltis DE, Stevens PF, Westoby M, Wright IJ, Aarssen L, Bertin RI, Calaminus A, Govaerts R, Hemmings F, Leishman MR, Oleksyn J, Soltis PS, Swenson NG, Warman L, Beaulieu JM. Corrigendum: Three keys to the radiation of angiosperms into freezing environments. Nature. 2015 May 21;521(7552):380. doi: 10.1038/nature14371. PMID: 25993966.
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A new Acid-Fast Streptothrix, Pathogenic to Man and Animals.

The Journal of hygiene

Birt C, Leishman WB.
PMID: 20474140
J Hyg (Lond). 1902 Apr 01;2(2):120-128.1. doi: 10.1017/s0022172400001868.

No abstract available.

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Birt C, Leishman WB. A new Acid-Fast Streptothrix, Pathogenic to Man and Animals. J Hyg (Lond). 1902;2(2):120-128.1doi: 10.1017/s0022172400001868.
Birt, C., & Leishman, W. B. (1902). A new Acid-Fast Streptothrix, Pathogenic to Man and Animals. The Journal of hygiene, 2(2), 120-128.1. https://doi.org/10.1017/s0022172400001868
Birt, C, and Leishman, W B. "A new Acid-Fast Streptothrix, Pathogenic to Man and Animals." The Journal of hygiene vol. 2,2 (1902): 120-128.1. doi: https://doi.org/10.1017/s0022172400001868
Birt C, Leishman WB. A new Acid-Fast Streptothrix, Pathogenic to Man and Animals. J Hyg (Lond). 1902 Apr 01;2(2):120-128.1. doi: 10.1017/s0022172400001868. PMID: 20474140; PMCID: PMC2236029.
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A Method of producing Chromatin Staining in Sections.

The Journal of hygiene

Leishman WB.
PMID: 20474199
J Hyg (Lond). 1904 Jul;4(3):434-6. doi: 10.1017/s0022172400002217.

No abstract available.

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Leishman WB. A Method of producing Chromatin Staining in Sections. J Hyg (Lond). 1904;4(3):434-6doi: 10.1017/s0022172400002217.
Leishman, W. B. (1904). A Method of producing Chromatin Staining in Sections. The Journal of hygiene, 4(3), 434-6. https://doi.org/10.1017/s0022172400002217
Leishman, W B. "A Method of producing Chromatin Staining in Sections." The Journal of hygiene vol. 4,3 (1904): 434-6. doi: https://doi.org/10.1017/s0022172400002217
Leishman WB. A Method of producing Chromatin Staining in Sections. J Hyg (Lond). 1904 Jul;4(3):434-6. doi: 10.1017/s0022172400002217. PMID: 20474199; PMCID: PMC2236032.
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Hodgkin's disease of the stomach.

Gastroenterology

LEHMAN DJ, HAWKES SZ.
PMID: 15393867
Gastroenterology. 1949 Nov;13(5):464-7.

No abstract available.

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LEHMAN DJ, HAWKES SZ. Hodgkin's disease of the stomach. Gastroenterology. 1949;13(5):464-7
LEHMAN, D. J., & HAWKES, S. Z. (1949). Hodgkin's disease of the stomach. Gastroenterology, 13(5), 464-7.
LEHMAN, D J, and HAWKES, S Z. "Hodgkin's disease of the stomach." Gastroenterology vol. 13,5 (1949): 464-7.
LEHMAN DJ, HAWKES SZ. Hodgkin's disease of the stomach. Gastroenterology. 1949 Nov;13(5):464-7. PMID: 15393867.
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Ge(Li) gamma-ray spectrometry as a pilot for NaI(Tl) gamma-ray spectrometry.

Talanta

Guinn VP, Graber FM, Fleishman DM.
PMID: 18960419
Talanta. 1968 Nov;15(11):1159-63. doi: 10.1016/0039-9140(68)80039-6.

Lithium-drifted germanium semiconductor detectors give much better resolution than do thallium-activated sodium iodide detectors, but much lower sensitivity. They can often advantageously be used in conjunction with NaI(Tl) detectors, to show whether corrections must be applied for activities other...

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Guinn VP, Graber FM, Fleishman DM. Ge(Li) gamma-ray spectrometry as a pilot for NaI(Tl) gamma-ray spectrometry. Talanta. 1968;15(11):1159-63doi: 10.1016/0039-9140(68)80039-6.
Guinn, V. P., Graber, F. M., & Fleishman, D. M. (1968). Ge(Li) gamma-ray spectrometry as a pilot for NaI(Tl) gamma-ray spectrometry. Talanta, 15(11), 1159-63. https://doi.org/10.1016/0039-9140(68)80039-6
Guinn, V P, et al. "Ge(Li) gamma-ray spectrometry as a pilot for NaI(Tl) gamma-ray spectrometry." Talanta vol. 15,11 (1968): 1159-63. doi: https://doi.org/10.1016/0039-9140(68)80039-6
Guinn VP, Graber FM, Fleishman DM. Ge(Li) gamma-ray spectrometry as a pilot for NaI(Tl) gamma-ray spectrometry. Talanta. 1968 Nov;15(11):1159-63. doi: 10.1016/0039-9140(68)80039-6. PMID: 18960419.
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The Application of Romanowsky's Stain in Malaria.

British medical journal

Leishman WB.
PMID: 20759490
Br Med J. 1901 Mar 16;1(2098):635-7. doi: 10.1136/bmj.1.2098.635.

No abstract available.

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Leishman WB. The Application of Romanowsky's Stain in Malaria. Br Med J. 1901;1(2098):635-7doi: 10.1136/bmj.1.2098.635.
Leishman, W. B. (1901). The Application of Romanowsky's Stain in Malaria. British medical journal, 1(2098), 635-7. https://doi.org/10.1136/bmj.1.2098.635
Leishman, W B. "The Application of Romanowsky's Stain in Malaria." British medical journal vol. 1,2098 (1901): 635-7. doi: https://doi.org/10.1136/bmj.1.2098.635
Leishman WB. The Application of Romanowsky's Stain in Malaria. Br Med J. 1901 Mar 16;1(2098):635-7. doi: 10.1136/bmj.1.2098.635. PMID: 20759490; PMCID: PMC2400673.
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FOUR DIFFERENT TYPES OF BLOOD SUGAR CURVE IN ONE PATIENT WITHIN SEVENTEEN MONTHS.

British medical journal

Lishman FJ.
PMID: 20775670
Br Med J. 1930 Aug 30;2(3634):318. doi: 10.1136/bmj.2.3634.318.

No abstract available.

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Lishman FJ. FOUR DIFFERENT TYPES OF BLOOD SUGAR CURVE IN ONE PATIENT WITHIN SEVENTEEN MONTHS. Br Med J. 1930;2(3634):318doi: 10.1136/bmj.2.3634.318.
Lishman, F. J. (1930). FOUR DIFFERENT TYPES OF BLOOD SUGAR CURVE IN ONE PATIENT WITHIN SEVENTEEN MONTHS. British medical journal, 2(3634), 318. https://doi.org/10.1136/bmj.2.3634.318
Lishman, F J. "FOUR DIFFERENT TYPES OF BLOOD SUGAR CURVE IN ONE PATIENT WITHIN SEVENTEEN MONTHS." British medical journal vol. 2,3634 (1930): 318. doi: https://doi.org/10.1136/bmj.2.3634.318
Lishman FJ. FOUR DIFFERENT TYPES OF BLOOD SUGAR CURVE IN ONE PATIENT WITHIN SEVENTEEN MONTHS. Br Med J. 1930 Aug 30;2(3634):318. doi: 10.1136/bmj.2.3634.318. PMID: 20775670; PMCID: PMC2450436.
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Electron-scale dynamics of the diffusion region during symmetric magnetic reconnection in space.

Science (New York, N.Y.)

Torbert RB, Burch JL, Phan TD, Hesse M, Argall MR, Shuster J, Ergun RE, Alm L, Nakamura R, Genestreti KJ, Gershman DJ, Paterson WR, Turner DL, Cohen I, Giles BL, Pollock CJ, Wang S, Chen LJ, Stawarz JE, Eastwood JP, Hwang KJ, Farrugia C, Dors I, Vaith H, Mouikis C, Ardakani A, Mauk BH, Fuselier SA, Russell CT, Strangeway RJ, Moore TE, Drake JF, Shay MA, Khotyaintsev YV, Lindqvist PA, Baumjohann W, Wilder FD, Ahmadi N, Dorelli JC, Avanov LA, Oka M, Baker DN, Fennell JF, Blake JB, Jaynes AN, Le Contel O, Petrinec SM, Lavraud B, Saito Y.
PMID: 30442767
Science. 2018 Dec 21;362(6421):1391-1395. doi: 10.1126/science.aat2998. Epub 2018 Nov 15.

Magnetic reconnection is an energy conversion process that occurs in many astrophysical contexts including Earth's magnetosphere, where the process can be investigated in situ by spacecraft. On 11 July 2017, the four Magnetospheric Multiscale spacecraft encountered a reconnection site...

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Torbert RB, Burch JL, Phan TD, et al. Electron-scale dynamics of the diffusion region during symmetric magnetic reconnection in space. Science. 2018;362(6421):1391-1395doi: 10.1126/science.aat2998.
Torbert, R. B., Burch, J. L., Phan, T. D., Hesse, M., Argall, M. R., Shuster, J., Ergun, R. E., Alm, L., Nakamura, R., Genestreti, K. J., Gershman, D. J., Paterson, W. R., Turner, D. L., Cohen, I., Giles, B. L., Pollock, C. J., Wang, S., Chen, L. J., Stawarz, J. E., Eastwood, J. P., Hwang, K. J., Farrugia, C., Dors, I., Vaith, H., Mouikis, C., Ardakani, A., Mauk, B. H., Fuselier, S. A., Russell, C. T., Strangeway, R. J., Moore, T. E., Drake, J. F., Shay, M. A., Khotyaintsev, Y. V., Lindqvist, P. A., Baumjohann, W., Wilder, F. D., Ahmadi, N., Dorelli, J. C., Avanov, L. A., Oka, M., Baker, D. N., Fennell, J. F., Blake, J. B., Jaynes, A. N., Le Contel, O., Petrinec, S. M., Lavraud, B., & Saito, Y. (2018). Electron-scale dynamics of the diffusion region during symmetric magnetic reconnection in space. Science (New York, N.Y.), 362(6421), 1391-1395. https://doi.org/10.1126/science.aat2998
Torbert, R B, et al. "Electron-scale dynamics of the diffusion region during symmetric magnetic reconnection in space." Science (New York, N.Y.) vol. 362,6421 (2018): 1391-1395. doi: https://doi.org/10.1126/science.aat2998
Torbert RB, Burch JL, Phan TD, Hesse M, Argall MR, Shuster J, Ergun RE, Alm L, Nakamura R, Genestreti KJ, Gershman DJ, Paterson WR, Turner DL, Cohen I, Giles BL, Pollock CJ, Wang S, Chen LJ, Stawarz JE, Eastwood JP, Hwang KJ, Farrugia C, Dors I, Vaith H, Mouikis C, Ardakani A, Mauk BH, Fuselier SA, Russell CT, Strangeway RJ, Moore TE, Drake JF, Shay MA, Khotyaintsev YV, Lindqvist PA, Baumjohann W, Wilder FD, Ahmadi N, Dorelli JC, Avanov LA, Oka M, Baker DN, Fennell JF, Blake JB, Jaynes AN, Le Contel O, Petrinec SM, Lavraud B, Saito Y. Electron-scale dynamics of the diffusion region during symmetric magnetic reconnection in space. Science. 2018 Dec 21;362(6421):1391-1395. doi: 10.1126/science.aat2998. Epub 2018 Nov 15. PMID: 30442767.
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