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Showing 1 to 11 of 11 entries
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Correlations between gametophytic (pollen) and sporophytic (seed) generations for polyunsaturated fatty acids in oilseed rape Brassica napus L.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Evans DE, Rothnie NE, Sang JP, Palmer MV, Mulcahy DL, Singh MB, Knox RB.
PMID: 24232206
Theor Appl Genet. 1988 Sep;76(3):411-9. doi: 10.1007/BF00265342.

Lipids were extracted from the diploid seed and haploid pollen of Brassica napus L. Two fractions of pollen lipids, namely the diploid-specified pollen-coat and the haploid-specified internal cytoplasmic lipids were obtained. Significant correlations exist between pollen and seed generations...

Neutralization of Heparin After Perfusion.

British medical journal

Rothnie NG, Kinmonth JB.
PMID: 20788968
Br Med J. 1960 Oct 22;2(5207):1194-7. doi: 10.1136/bmj.2.5207.1194.

No abstract available.

Membrane protein extraction and purification using partially-esterified SMA polymers.

Biochimica et biophysica acta. Biomembranes

Hawkins OP, Jahromi CPT, Gulamhussein AA, Nestorow S, Bahra T, Shelton C, Owusu-Mensah QK, Mohiddin N, O'Rourke H, Ajmal M, Byrnes K, Khan M, Nahar NN, Lim A, Harris C, Healy H, Hasan SW, Ahmed A, Evans L, Vaitsopoulou A, Akram A, Williams C, Binding J, Thandi RK, Joby A, Guest A, Tariq MZ, Rasool F, Cavanagh L, Kang S, Asparuhov B, Jestin A, Dafforn TR, Simms J, Bill RM, Goddard AD, Rothnie AJ.
PMID: 34480878
Biochim Biophys Acta Biomembr. 2021 Dec 01;1863(12):183758. doi: 10.1016/j.bbamem.2021.183758. Epub 2021 Sep 01.

Styrene maleic acid (SMA) polymers have proven to be very successful for the extraction of membrane proteins, forming SMA lipid particles (SMALPs), which maintain a lipid bilayer around the membrane protein. SMALP-encapsulated membrane proteins can be used for functional...

Recording of hospitalizations for acute exacerbations of COPD in UK electronic health care records.

Clinical epidemiology

Rothnie KJ, Müllerová H, Thomas SL, Chandan JS, Smeeth L, Hurst JR, Davis K, Quint JK.
PMID: 27920578
Clin Epidemiol. 2016 Nov 21;8:771-782. doi: 10.2147/CLEP.S117867. eCollection 2016.

BACKGROUND: Accurate identification of hospitalizations for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) within electronic health care records is important for research, public health, and to inform health care utilization and service provision. We aimed to develop a...

Biological insights from SMA-extracted proteins.

Biochemical Society transactions

Unger L, Ronco-Campaña A, Kitchen P, Bill RM, Rothnie AJ.
PMID: 34110372
Biochem Soc Trans. 2021 Jun 30;49(3):1349-1359. doi: 10.1042/BST20201067.

In the twelve years since styrene maleic acid (SMA) was first used to extract and purify a membrane protein within a native lipid bilayer, this technological breakthrough has provided insight into the structural and functional details of protein-lipid interactions....

A Study of Phospholipids and Galactolipids in Pollen of Two Lines of Brassica napus L. (Rapeseed) with Different Ratios of Linoleic to Linolenic Acid.

Plant physiology

Evans DE, Sang JP, Cominos X, Rothnie NE, Knox RB.
PMID: 16667482
Plant Physiol. 1990 Jun;93(2):418-24. doi: 10.1104/pp.93.2.418.

The phospholipids and galactolipids of the pollen-coat and internal domains of two lines of Brassica napus, Wesroona and IXLIN, with different linoleic/linolenic acid ratios (18:2/18:3) have been characterized by normal phase silica high performance liquid chromatography and gas liquid...

Chronic obstructive pulmonary disease and acute myocardial infarction: effects on presentation, management, and outcomes.

European heart journal. Quality of care & clinical outcomes

Rothnie KJ, Quint JK.
PMID: 29474627
Eur Heart J Qual Care Clin Outcomes. 2016 Apr 01;2(2):81-90. doi: 10.1093/ehjqcco/qcw005.

Cardiovascular disease is a common cause of death in patients with chronic obstructive pulmonary disease (COPD) and is a key target for improving outcomes. However, there are concerns that patients with COPD may not have enjoyed the same mortality...

High rates of therapeutic changes in patients with psoriatic arthritis receiving treatment with disease-modifying antirheumatic drugs: A cross-sectional study.

Modern rheumatology

Behrens F, Rech J, Thaçi D, Zinke S, Rothnie KJ, Oefner Daamen C, Leipe J.
PMID: 32856975
Mod Rheumatol. 2021 Aug 26;1-9. doi: 10.1080/14397595.2020.1816597. Epub 2021 Aug 26.

OBJECTIVES: To characterize treatment patterns for patients with psoriatic arthritis (PsA) currently receiving any disease-modifying antirheumatic drug (DMARD).METHODS: The RESULTS: Mean age of the 316 patients was 55.1 years and mean PsA disease duration was 9.9 years. PsA activity...

High rates of therapeutic changes in patients with psoriatic arthritis receiving treatment with disease-modifying antirheumatic drugs: A cross-sectional study.

Modern rheumatology

Behrens F, Rech J, Thaçi D, Zinke S, Rothnie KJ, Oefner Daamen C, Leipe J.
PMID: 34922390
Mod Rheumatol. 2021 Aug 26; doi: 10.1080/14397595.2020.1816597. Epub 2021 Aug 26.

OBJECTIVES: To characterize treatment patterns for patients with psoriatic arthritis (PsA) currently receiving any disease-modifying antirheumatic drug (DMARD).METHODS: The Strategy for Psoriatic Arthritis In Germany (SPAIG) study was a retrospective observational study conducted from May to November 2017 at...

Membrane protein extraction and purification using partially-esterified SMA polymers.

Biochimica et biophysica acta. Biomembranes

Hawkins OP, Jahromi CPT, Gulamhussein AA, Nestorow S, Bahra T, Shelton C, Owusu-Mensah QK, Mohiddin N, O'Rourke H, Ajmal M, Byrnes K, Khan M, Nahar NN, Lim A, Harris C, Healy H, Hasan SW, Ahmed A, Evans L, Vaitsopoulou A, Akram A, Williams C, Binding J, Thandi RK, Joby A, Guest A, Tariq MZ, Rasool F, Cavanagh L, Kang S, Asparuhov B, Jestin A, Dafforn TR, Simms J, Bill RM, Goddard AD, Rothnie AJ.
PMID: 34480878
Biochim Biophys Acta Biomembr. 2021 Dec 01;1863(12):183758. doi: 10.1016/j.bbamem.2021.183758. Epub 2021 Sep 01.

Styrene maleic acid (SMA) polymers have proven to be very successful for the extraction of membrane proteins, forming SMA lipid particles (SMALPs), which maintain a lipid bilayer around the membrane protein. SMALP-encapsulated membrane proteins can be used for functional...

Mortality after admission for heart failure in the UK compared with Japan.

Open heart

Nagai T, Sundaram V, Rothnie K, Quint JK, Shoaib A, Shiraishi Y, Kohsaka S, Piper S, McDonagh TA, Hardman SMC, Goda A, Mizuno A, Kohno T, Rigby AS, Yoshikawa T, Clark AL, Anzai T, Cleland JGF.
PMID: 30228905
Open Heart. 2018 Sep 11;5(2):e000811. doi: 10.1136/openhrt-2018-000811. eCollection 2018.

OBJECTIVE: Mortality amongst patients hospitalised for heart failure (HHF) in Western and Asian countries may differ, but this has not been investigated using individual patient-level data (IPLD). We sought to remedy this through rigorous statistical analysis of HHF registries...

Showing 1 to 11 of 11 entries