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Showing 1 to 12 of 32 entries
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The role of novel biomarkers in predicting diabetic nephropathy: a review.

International journal of nephrology and renovascular disease

Uwaezuoke SN.
PMID: 28860837
Int J Nephrol Renovasc Dis. 2017 Aug 17;10:221-231. doi: 10.2147/IJNRD.S143186. eCollection 2017.

Diabetic nephropathy (DN) is one of the microvascular complications of the kidney arising commonly from type 1 diabetes mellitus (T1DM), and occasionally from type 2 diabetes mellitus (T2DM). Microalbuminuria serves as an early indicator of DN risk and a...

First report of OXA-181 and NDM-1 from a clinical Klebsiella pneumoniae isolate from Nigeria.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Uwaezuoke NS, Kieffer N, Iregbu KC, Nordmann P.
PMID: 28526566
Int J Infect Dis. 2017 Aug;61:1-2. doi: 10.1016/j.ijid.2017.05.004. Epub 2017 May 16.

No abstract available.

Giant neoplastic omental cyst masquerading as ascites: a case report.

Cases journal

Rahman GA, Abdulkadir AY, Olatoke SA, Uwaezuoke S, Yusuf IF, Braimoh KT.
PMID: 19918526
Cases J. 2009 Sep 16;2:6482. doi: 10.4076/1757-1626-2-6482.

INTRODUCTION: Cystic lesion of the omentum and mesentery are rare. The incidence of both cyst types has been variously reported to vary from 1/27,000-100,000 hospital admission. Omental cysts occur three to ten times less frequently than mesenteric cyst. Preoperative...

Prognostic scores and biomarkers for pediatric community-acquired pneumonia: how far have we come?.

Pediatric health, medicine and therapeutics

Uwaezuoke SN, Ayuk AC.
PMID: 29388605
Pediatric Health Med Ther. 2017 Feb 20;8:9-18. doi: 10.2147/PHMT.S126001. eCollection 2017.

This article aimed to review the current prognostic and diagnostic tools used for community-acquired pneumonia (CAP) and highlight those potentially applicable in children with CAP. Several scoring systems have been developed to predict CAP mortality risk and serve as...

Vaso-occlusive crisis in sickle cell disease: current paradigm on pain management.

Journal of pain research

Uwaezuoke SN, Ayuk AC, Ndu IK, Eneh CI, Mbanefo NR, Ezenwosu OU.
PMID: 30588066
J Pain Res. 2018 Dec 11;11:3141-3150. doi: 10.2147/JPR.S185582. eCollection 2018.

This narrative review aims to highlight the current paradigm on pain management in sickle cell vaso-occlusive crisis. It specifically examines the pathophysiologic mechanisms of sickle cell pain as well as the pharmacologic and nonpharmacologic methods of pain management. Recurrent...

Relationship between disease severity and folate status of children with sickle cell anaemia in Enugu, South East Nigeria.

African health sciences

Nnajekwu UC, Nnajekwu CO, Onukwuli VO, Uwaezuoke NA, Ezenwosu OU, Ikefuna AN, Emodi IJ.
PMID: 34795733
Afr Health Sci. 2021 Jun;21(2):759-764. doi: 10.4314/ahs.v21i2.35.

BACKGROUND: Repeated crises in children with sickle cell anaemia (SCA), which is a manifestation of disease severity, results in depletion of their minimal tissue folate stores, with higher likelihood of folate deficiency. The study aimed to determine the relationship...

Standardization of .

Therapeutic advances in infectious disease

Oladele RO, Otu AA, Balogun OJ, Babalola OM, Nwosu AO, Iyabo Osaigbovo I, Gbajabiamila T, Irurhe NK, Fayemiwo SA, Shettima SA, Uwaezuoke NS, Edwin CP, Ayanbeku TS, Okaa JU, Elikwu CJ, Denning DW, Kanki PJ, Ogunsola FT.
PMID: 34646555
Ther Adv Infect Dis. 2021 Oct 09;8:20499361211050158. doi: 10.1177/20499361211050158. eCollection 2021.

BACKGROUND AND OBJECTIVES: Commercial METHODS: Sera from 519 prospectively recruited healthy blood donors and 39 previously confirmed cases of CPA were analysed for RESULTS: Among healthy blood donors, 141 (27.2%) were aged 16-25 years with median (interquartile range, IQR)...

Clinical depression in children and adolescents with sickle cell anaemia: influencing factors in a resource-limited setting.

BMC pediatrics

Ezenwosu O, Chukwu B, Ezenwosu I, Uwaezuoke N, Eke C, Udorah M, Idoko C, Ikefuna A, Emodi I.
PMID: 34847910
BMC Pediatr. 2021 Dec 01;21(1):533. doi: 10.1186/s12887-021-03015-1.

BACKGROUND: Sickle cell anaemia (SCA) is the commonest monogenic haematologic disorder resulting from the inheritance of homozygous mutant haemoglobin genes from both parents. Some factors have been identified as important in explaining the variability in depression in sickle cell...

Negative Marking and the Student Physician--A Descriptive Study of Nigerian Medical Schools.

Journal of medical education and curricular development

Ndu IK, Ekwochi U, Di Osuorah C, Asinobi IN, Nwaneri MO, Uwaezuoke SN, Amadi OF, Okeke IB, Chinawa JM, Orjioke CJG.
PMID: 29349304
J Med Educ Curric Dev. 2016 Nov 13;3. doi: 10.4137/JMECD.S40705. eCollection 2016.

BACKGROUND: There is considerable debate about the two most commonly used scoring methods, namely, the formula scoring (popularly referred to as negative marking method in our environment) and number right scoring methods. Although the negative marking scoring system attempts...

Prevalence rates of histopathologic subtypes associated with steroid resistance in childhood nephrotic syndrome in Sub-Saharan Africa: a systematic review.

International journal of nephrology and renovascular disease

Uwaezuoke SN, Ndu IK, Mbanefo NR.
PMID: 31372025
Int J Nephrol Renovasc Dis. 2019 Jul 08;12:167-176. doi: 10.2147/IJNRD.S207372. eCollection 2019.

INTRODUCTION: The prevalence rates of the common histopathologic subtypes of childhood nephrotic syndrome associated with steroid resistance appear to be changing globally. In Sub Saharan Africa (SSA), the trend is similar over the past few decades.AIM: This systematic review...

Application and Characterization of Gum from Bombax buonopozense Calyxes as an Excipient in Tablet Formulation.

Pharmaceutics

Ngwuluka NC, Kyari J, Taplong J, Uwaezuoke OJ.
PMID: 24300296
Pharmaceutics. 2012 Aug 03;4(3):354-65. doi: 10.3390/pharmaceutics4030354.

This study was undertaken to explore gum from Bombax buonopozense calyxes as a binding agent in formulation of immediate release dosage forms using wet granulation method. The granules were characterized to assess the flow and compression properties and when...

Somatization disorder among adolescents in southeast Nigeria: a neglected issue.

International journal of mental health systems

Nwokocha ARC, Chinawa JM, Onukwuli V, Ubesie A, Ndukuba A, Chinawa AT, Aniwada E, Uwaezuoke S.
PMID: 28947913
Int J Ment Health Syst. 2017 Sep 21;11:57. doi: 10.1186/s13033-017-0161-3. eCollection 2017.

BACKGROUND: Adolescents do present with somatization disorder which is often neglected by pediatricians. This could have serious consequences if not curbed early.OBJECTIVES: This study is aimed at determining the pattern and types of Somatization disorder among adolescents attending secondary...

Showing 1 to 12 of 32 entries