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The concerted addition of HBr to aryl alkynes; orthogonal pi bond selectivity.

Organic & biomolecular chemistry

Weiss HM, Touchette KM, Angell S, Khan J.
PMID: 12945906
Org Biomol Chem. 2003 Jun 21;1(12):2152-6. doi: 10.1039/b300045a.

In a weakly acidic solution, the addition of HBr to 1-phenylprop-1-yne produces predominantly the anti-Markovnikov product. In this paper, we consider five possible explanations for this behavior and conclude that the concerted addition is occurring on the acetylenic pi...

A handy form to evaluate staffers.


Weiss GG.
PMID: 15600025
RN. 2004 Nov;67(11):suppl 2-3.

No abstract available.

Drug treatment of microsporidiosis.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Costa SF, Weiss LM.
PMID: 11498405
Drug Resist Updat. 2000 Dec;3(6):384-399. doi: 10.1054/drup.2000.0174.

Microsporidia are ubiquitous organisms that are emerging pathogens in humans. These are most likely zoonotic and/or waterborne infections. In the immunosuppressed host, such as those treated with immunosuppressive drugs or infected with human immunodeficiency virus particularly at advanced stages...

Children, Pregnant Women and the Culture of Malaria in Two Rural Communities of Ghana.

Anthropology & medicine

Ahorlu CK, Koram KA, Weiss MG.
PMID: 27268391
Anthropol Med. 2007 Aug;14(2):167-81. doi: 10.1080/13648470701381473.

The Malaria situation in Ghana is typical of many tropical African countries, where it remains a major cause of morbidity and mortality. Control methods generally emphasize prompt diagnosis and treatment. However, local experiences and meanings continue to influence help-seeking...

Health anthropology and urban health research.

Anthropology & medicine

Obrist B, VAN Eeuwijk P, Weiss MG.
PMID: 26954982
Anthropol Med. 2003 Dec 01;10(3):267-74. doi: 10.1080/1364847032000133816.

We live in a rapidly urbanising world. According to the 2001 statistics of the United Nations,a the proportion of urban dwellers rose from 30% in 1950 to 47% in 2000 and will probably attain 60% in 2030. Almost 70%...

Increased Hydrogel Swelling Induced by Absorption of Small Molecules.

ACS applied materials & interfaces

Nam C, Zimudzi TJ, Geise GM, Hickner MA.
PMID: 27159118
ACS Appl Mater Interfaces. 2016 Jun 08;8(22):14263-70. doi: 10.1021/acsami.6b02069. Epub 2016 May 24.

The water and small molecule uptake behavior of amphiphilic diacrylate terminated poly(dimethylsiloxane) (PDMSDA)/poly(ethylene glycol diacrylate) (PEGDA) cross-linked hydrogels were studied using attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. These hydrogel networks absorbed more water as the PEGDA content of...

The STING agonist DMXAA triggers a cooperation between T lymphocytes and myeloid cells that leads to tumor regression.


Weiss JM, Guérin MV, Regnier F, Renault G, Galy-Fauroux I, Vimeux L, Feuillet V, Peranzoni E, Thoreau M, Trautmann A, Bercovici N.
PMID: 29123960
Oncoimmunology. 2017 Jul 07;6(10):e1346765. doi: 10.1080/2162402X.2017.1346765. eCollection 2017.

Regressing tumors are usually associated with a large immune infiltrate, but the molecular and cellular interactions that govern a successful anti-tumor immunity remain elusive. Here, we have triggered type I Interferon (IFN) signaling in a breast tumor model (MMTV-PyMT)...

Biallelic Mutations in ADPRHL2, Encoding ADP-Ribosylhydrolase 3, Lead to a Degenerative Pediatric Stress-Induced Epileptic Ataxia Syndrome.

American journal of human genetics

Ghosh SG, Becker K, Huang H, Dixon-Salazar T, Chai G, Salpietro V, Al-Gazali L, Waisfisz Q, Wang H, Vaux KK, Stanley V, Manole A, Akpulat U, Weiss MM, Efthymiou S, Hanna MG, Minetti C, Striano P, Pisciotta L, De Grandis E, Altmüller J, Nürnberg P, Thiele H, Yis U, Okur TD, Polat AI, Amiri N, Doosti M, Karimani EG, Toosi MB, Haddad G, Karakaya M, Wirth B, van Hagen JM, Wolf NI, Maroofian R, Houlden H, Cirak S, Gleeson JG.
PMID: 30100084
Am J Hum Genet. 2018 Sep 06;103(3):431-439. doi: 10.1016/j.ajhg.2018.07.010. Epub 2018 Aug 09.

ADP-ribosylation, the addition of poly-ADP ribose (PAR) onto proteins, is a response signal to cellular challenges, such as excitotoxicity or oxidative stress. This process is catalyzed by a group of enzymes referred to as poly(ADP-ribose) polymerases (PARPs). Because the...

Addressing intravaginal practices in women with HIV and at-risk for HIV infection, a mixed methods pilot study.

International journal of women's health

Alcaide ML, Rodriguez VJ, Fischl MA, Jones DL, Weiss SM.
PMID: 28280394
Int J Womens Health. 2017 Feb 28;9:123-132. doi: 10.2147/IJWH.S125883. eCollection 2017.

Intravaginal practices (IVPs), include intravaginal cleansing (cleansing the inside of the vagina) or intravaginal insertion of products for hygiene, health or sexuality reasons. IVPs are associated with adverse female health outcomes, development of bacterial vaginosis, HIV acquisition and transmission....

Fertility intentions of prenatal and postpartum HIV-positive women in primary care in Mpumalanga province, South Africa: a longitudinal study.

HIV/AIDS (Auckland, N.Z.)

Peltzer K, Sifunda S, Mandell LN, Rodriguez VJ, Lee TK, Cook R, Weiss SM, Jones DL.
PMID: 29497335
HIV AIDS (Auckl). 2018 Feb 16;10:9-17. doi: 10.2147/HIV.S153212. eCollection 2018.

INTRODUCTION: This study aimed to assess fertility intentions (planning to have more children in the future) and associated factors among pregnant and postpartum HIV positive women in rural South Africa.METHODS: In a longitudinal study, as part of a prevention...

History of Preeclampsia Adds to the Deleterious Effect of Chronic Stress on the Cardiac Ability to Flexibly Adapt to Challenge.

Frontiers in physiology

Lackner HK, Moertl MG, Schmid-Zalaudek K, Lucovnik M, Weiss EM, Kolovetsiou-Kreiner V, Papousek I.
PMID: 30233410
Front Physiol. 2018 Sep 03;9:1237. doi: 10.3389/fphys.2018.01237. eCollection 2018.

Preeclampsia, a pregnancy-specific disorder, presents a major health problem during gestation, but is also associated with increased risk for cardiovascular complications in later life. We aimed to investigate whether chronic stress experience and preeclampsia may have additive adverse effects...

Targeting Calpain for Heart Failure Therapy: Implications From Multiple Murine Models.

JACC. Basic to translational science

Wang Y, Chen B, Huang CK, Guo A, Wu J, Zhang X, Chen R, Chen C, Kutschke W, Weiss RM, Boudreau RL, Margulies KB, Hong J, Song LS.
PMID: 30175274
JACC Basic Transl Sci. 2018 Aug 28;3(4):503-517. doi: 10.1016/j.jacbts.2018.05.004. eCollection 2018 Aug.

Heart failure remains a major cause of morbidity and mortality in developed countries. There is still a strong need to devise new mechanism-based treatments for heart failure. Numerous studies have suggested the importance of the Ca

Showing 1 to 12 of 553 entries