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Showing 1 to 12 of 155 entries
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Regulated lysosomal exocytosis mediates cancer progression.

Science advances

Machado E, White-Gilbertson S, van de Vlekkert D, Janke L, Moshiach S, Campos Y, Finkelstein D, Gomero E, Mosca R, Qiu X, Morton CL, Annunziata I, d'Azzo A.
PMID: 26824057
Sci Adv. 2015 Dec 18;1(11):e1500603. doi: 10.1126/sciadv.1500603. eCollection 2015 Dec.

Understanding how tumor cells transition to an invasive and drug-resistant phenotype is central to cancer biology, but the mechanisms underlying this transition remain unclear. We show that sarcomas gain these malignant traits by inducing lysosomal exocytosis, a ubiquitous physiological...

Monitoring TriAcylGlycerols Accumulation by Atomic Force Microscopy Based Infrared Spectroscopy in Streptomyces Species for Biodiesel Applications.

The journal of physical chemistry letters

Deniset-Besseau A, Prater CB, Virolle MJ, Dazzi A.
PMID: 26270832
J Phys Chem Lett. 2014 Feb 20;5(4):654-8. doi: 10.1021/jz402393a. Epub 2014 Jan 31.

An atomic force microscope coupled with a tunable infrared laser source (AFM-IR) was used to measure the size and map the distribution of oil inclusions inside of microorganism without staining or other special sample preparation. The microorganism under study...

Isotopic composition of sheep wool records seasonality of climate and diet.

Rapid communications in mass spectrometry : RCM

Zazzo A, Cerling TE, Ehleringer JR, Moloney AP, Monahan FJ, Schmidt O.
PMID: 26147475
Rapid Commun Mass Spectrom. 2015 Aug 15;29(15):1357-69. doi: 10.1002/rcm.7228.

RATIONALE: Hair keratin is a very important material in ecological and archaeological studies because it grows continuously, can be obtained non-invasively, does not require extensive processing prior to analysis and can be found in archaeological sites. Only a few...

Neuraminidase-1 mediates skeletal muscle regeneration.

Biochimica et biophysica acta

Neves Jde C, Rizzato VR, Fappi A, Garcia MM, Chadi G, van de Vlekkert D, d'Azzo A, Zanoteli E.
PMID: 26001931
Biochim Biophys Acta. 2015 Sep;1852(9):1755-64. doi: 10.1016/j.bbadis.2015.05.006. Epub 2015 May 19.

Neuraminidase-1 (NEU1) is the sialidase responsible for the catabolism of sialoglycoconjugates in lysosomes. Congenital NEU1 deficiency causes sialidosis, a severe lysosomal storage disease associated with a broad spectrum of clinical manifestations, which also include skeletal deformities, skeletal muscle hypotonia...

Packing effects in 4,4'-bis(4-hydroxybutyl)-2,2'-bipyridine and 4,4'-bis(4-bromobutyl)-2,2'-bipyridine.

Acta crystallographica. Section C, Crystal structure communications

Iyer VM, Stoeckli-Evans H, D'Aléo A, De Cola L, Belser P.
PMID: 15805645
Acta Crystallogr C. 2005 Apr;61:o259-61. doi: 10.1107/S0108270105006438. Epub 2005 Mar 25.

Structure analyses of 4,4'-bis(4-hydroxybutyl)-2,2'-bipyridine, C18H24N2O2, (I), and 4,4'-bis(4-bromobutyl)-2,2'-bipyridine, C18H22Br2N2, (II), reveal intermolecular hydrogen bonding in both compounds. For (I), O-H...N intermolecular hydrogen bonding leads to the formation of an infinite two-dimensional polymer, and pi stacking interactions are also observed....

Author Correction: Lysosomal storage diseases.

Nature reviews. Disease primers

Platt FM, d'Azzo A, Davidson BL, Neufeld EF, Tifft CJ.
PMID: 30337566
Nat Rev Dis Primers. 2018 Oct 18;4(1):36. doi: 10.1038/s41572-018-0037-0.

In the version of the article originally published, in Figure 2 and the accompanying legend, LIMP 2 was incorrectly referred to as LIMP 1. The article has now been corrected.

Integration of stimulated Raman gain and stimulated Raman losses detection modes in a single nonlinear microscope.

Optics express

Ranjan R, D'arco A, Ferrara MA, Indolfi M, Larobina M, Sirleto L.
PMID: 30469721
Opt Express. 2018 Oct 01;26(20):26317-26326. doi: 10.1364/OE.26.026317.

This work addresses some key challenges in the fields of bio and nanophotonics by stimulated Raman microscopy. We present the design and the implementation of a femtosecond stimulated Raman scattering microscope, equipped with three femtosecond laser sources, which allows...

Radiocarbon dating minute amounts of bone (3-60 mg) with ECHoMICADAS.

Scientific reports

Cersoy S, Zazzo A, Rofes J, Tresset A, Zirah S, Gauthier C, Kaltnecker E, Thil F, Tisnerat-Laborde N.
PMID: 28769125
Sci Rep. 2017 Aug 02;7(1):7141. doi: 10.1038/s41598-017-07645-3.

Because hard tissues can be radiocarbon dated, they are key to establishing the archaeological chronologies, palaeoenvironmental reconstructions and historical-biogeographical processes of the last 50,000 years. The advent of accelerator mass spectrometers (AMS) has revolutionized the field of archaeology but...

Water Solubility Enhancement of Pyrazolo[3,4-.

ACS medicinal chemistry letters

Sanna M, Sicilia G, Alazzo A, Singh N, Musumeci F, Schenone S, Spriggs KA, Burley JC, Garnett MC, Taresco V, Alexander C.
PMID: 29541359
ACS Med Chem Lett. 2018 Jan 29;9(3):193-197. doi: 10.1021/acsmedchemlett.7b00456. eCollection 2018 Mar 08.

A miniaturized assay was optimized to evaluate the enhanced apparent water solubility of pyrazolo[3,4-

Characterization of volatile organic compounds (VOCs) in their liquid-phase by terahertz time-domain spectroscopy.

Biomedical optics express

D'Arco A, Fabrizio MD, Dolci V, Marcelli A, Petrarca M, Ventura GD, Lupi S.
PMID: 32010495
Biomed Opt Express. 2019 Dec 02;11(1):1-7. doi: 10.1364/BOE.11.000001. eCollection 2020 Jan 01.

In this work the terahertz spectra of benzene, toluene, p-xylene and styrene-four volatile organic compounds (VOCs) of interest in environmental pollution studies-have been measured in their liquid phase at room temperature using terahertz time-domain spectroscopy (THz-TDS). Their frequency-dependent refractive...

Construction and validation of competency frameworks for the training of nurses in emergencies.

Revista latino-americana de enfermagem

Miranda FBG, Mazzo A, Alves Pereira-Junior G.
PMID: 30379246
Rev Lat Am Enfermagem. 2018 Oct 25;26:e3061. doi: 10.1590/1518-8345.2631-3061.

OBJECTIVE: to build and validate competency frameworks to be developed in the training of nurses for the care of adult patients in situations of emergency with a focus on airway, breathing and circulation approach.METHOD: this is a descriptive and...

In-place molecular preservation of cellulose in 5,000-year-old archaeological textiles.

Proceedings of the National Academy of Sciences of the United States of America

Reynaud C, Thoury M, Dazzi A, Latour G, Scheel M, Li J, Thomas A, Moulhérat C, Didier A, Bertrand L.
PMID: 32747556
Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):19670-19676. doi: 10.1073/pnas.2004139117. Epub 2020 Aug 03.

The understanding of fossilization mechanisms at the nanoscale remains extremely challenging despite its fundamental interest and its implications for paleontology, archaeology, geoscience, and environmental and material sciences. The mineralization mechanism by which cellulosic, keratinous, and silk tissues fossilize in...

Showing 1 to 12 of 155 entries