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Showing 1 to 12 of 13 entries
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Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

Cell & bioscience

Lee JG, Huang W, Lee H, van de Leemput J, Kane MA, Han Z.
PMID: 33766124
Cell Biosci. 2021 Mar 25;11(1):58. doi: 10.1186/s13578-021-00568-7.

BACKGROUND: SARS-CoV-2 causes COVID-19 which has a widely diverse disease profile. The mechanisms underlying its pathogenicity remain unclear. We set out to identify the SARS-CoV-2 pathogenic proteins that through host interactions cause the cellular damages underlying COVID-19 symptomatology.METHODS: We...

Tunneling measurements on the high-Tc superconductors La1.85Sr.

Physical review. B, Condensed matter

Schreurs LW, Teunissen PA, van Bentum PJ, van de Leemput LE, van Kempen H.
PMID: 9942130
Phys Rev B Condens Matter. 1987 Jul 01;36(1):843-845. doi: 10.1103/physrevb.36.843.

No abstract available.

Single-electron tunneling observed with point-contact tunnel junctions.

Physical review letters

Teunissen PA, van Bentum PJ, van de Leemput LE, van Kempen H.
PMID: 10038524
Phys Rev Lett. 1988 Jan 25;60(4):369-372. doi: 10.1103/PhysRevLett.60.369.

No abstract available.

Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatment.

Cell & bioscience

Zhu JY, Lee JG, van de Leemput J, Lee H, Han Z.
PMID: 33766136
Cell Biosci. 2021 Mar 25;11(1):59. doi: 10.1186/s13578-021-00567-8.

BACKGROUND: SARS-CoV-2 causes COVID-19 with a widely diverse disease profile that affects many different tissues. The mechanisms underlying its pathogenicity in host organisms remain unclear. Animal models for studying the pathogenicity of SARS-CoV-2 proteins are lacking.METHODS: Using bioinformatic analysis,...

The rise and fall of rationality in language.

Proceedings of the National Academy of Sciences of the United States of America

Scheffer M, van de Leemput I, Weinans E, Bollen J.
PMID: 34916287
Proc Natl Acad Sci U S A. 2021 Dec 21;118(51). doi: 10.1073/pnas.2107848118.

The surge of post-truth political argumentation suggests that we are living in a special historical period when it comes to the balance between emotion and reasoning. To explore if this is indeed the case, we analyze language in millions...

High-field measurements on the high-Tc superconductors La1.85Sr0.15CuO4- delta and YBa2Cu3O7- delta.

Physical review. B, Condensed matter

Perenboom JA, Schreurs LW, Teunissen PA, van Bentum PJ, van de Leemput LE, van Kempen H.
PMID: 9942164
Phys Rev B Condens Matter. 1987 Oct 01;36(10):5279-5283. doi: 10.1103/physrevb.36.5279.

No abstract available.

Slow Recovery from Local Disturbances as an Indicator for Loss of Ecosystem Resilience.

Ecosystems (New York, N.Y.)

van de Leemput IA, Dakos V, Scheffer M, van Nes EH.
PMID: 31983890
Ecosystems. 2018;21(1):141-152. doi: 10.1007/s10021-017-0154-8. Epub 2017 Jun 02.

A range of indicators have been proposed for identifying the elevated risk of critical transitions in ecosystems. Most indicators are based on the idea that critical slowing down can be inferred from changes in statistical properties of natural fluctuations...

What does germane load mean? An empirical contribution to the cognitive load theory.

Frontiers in psychology

Debue N, van de Leemput C.
PMID: 25324806
Front Psychol. 2014 Oct 01;5:1099. doi: 10.3389/fpsyg.2014.01099. eCollection 2014.

While over the last decades, much attention has been paid to the mental workload in the field of human computer interactions, there is still a lack of consensus concerning the factors that generate it as well as the measurement...

Drosophila, a powerful model to study virus-host interactions and pathogenicity in the fight against SARS-CoV-2.

Cell & bioscience

van de Leemput J, Han Z.
PMID: 34120640
Cell Biosci. 2021 Jun 13;11(1):110. doi: 10.1186/s13578-021-00621-5.

The COVID-19 pandemic is having a tremendous impact on humanity. Although COVID-19 vaccines are showing promising results, they are not 100% effective and resistant mutant SARS-CoV-2 strains are on the rise. To successfully fight against SARS-CoV-2 and prepare for...

Video Game Addiction and Emotional States: Possible Confusion Between Pleasure and Happiness?.

Frontiers in psychology

Gros L, Debue N, Lete J, van de Leemput C.
PMID: 32047450
Front Psychol. 2020 Jan 27;10:2894. doi: 10.3389/fpsyg.2019.02894. eCollection 2019.

Internet gaming disorder is characterized by a severely reduced control over gaming, resulting in an increasing gaming time and leading to negative consequences in many aspects of the individual life: personal, family, social, occupational and other relevant areas of...

The rise and fall of rationality in language.

Proceedings of the National Academy of Sciences of the United States of America

Scheffer M, van de Leemput I, Weinans E, Bollen J.
PMID: 34916287
Proc Natl Acad Sci U S A. 2021 Dec 21;118(51). doi: 10.1073/pnas.2107848118.

The surge of post-truth political argumentation suggests that we are living in a special historical period when it comes to the balance between emotion and reasoning. To explore if this is indeed the case, we analyze language in millions...

Slit diaphragm maintenance requires dynamic clathrin-mediated endocytosis facilitated by AP-2, Lap, Aux and Hsc70-4 in nephrocytes.

Cell & bioscience

Wang L, Wen P, van de Leemput J, Zhao Z, Han Z.
PMID: 33975644
Cell Biosci. 2021 May 11;11(1):83. doi: 10.1186/s13578-021-00595-4.

BACKGROUND: The Slit diaphragm (SD) is the key filtration structure in human glomerular kidney that is affected in many types of renal diseases. SD proteins are known to undergo endocytosis and recycling to maintain the integrity of the filtration...

Showing 1 to 12 of 13 entries