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Drosophila Syncrip binds the gurken mRNA localisation signal and regulates localised transcripts during axis specification.

Biology open

McDermott SM, Meignin C, Rappsilber J, Davis I.
PMID: 23213441
Biol Open. 2012 May 15;1(5):488-97. doi: 10.1242/bio.2012885. Epub 2012 Apr 11.

In the Drosophila oocyte, mRNA transport and localised translation play a fundamental role in axis determination and germline formation of the future embryo. gurken mRNA encodes a secreted TGF-α signal that specifies dorsal structures, and is localised to the...

Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia.

Molecular therapy. Nucleic acids

Downie Ruiz Velasco A, Welten SMJ, Goossens EAC, Quax PHA, Rappsilber J, Michlewski G, Nossent AY.
PMID: 30665182
Mol Ther Nucleic Acids. 2019 Mar 01;14:329-338. doi: 10.1016/j.omtn.2018.11.017. Epub 2018 Dec 06.

After induction of ischemia in mice, 14q32 microRNAs are regulated in three distinct temporal patterns. These expression patterns, as well as basal expression levels, are independent of the microRNA genes' order in the 14q32 locus. This implies that posttranscriptional...

Showing 1 to 2 of 2 entries