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Showing 1 to 10 of 10 entries
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[The Role of Calcium Ion in Apotopsis of HL-60 Cells Induced by VP-16].

Zhongguo shi yan xue ye xue za zhi

Shi H, Li L, Yuan L, He Q, Wang S, Wang D.
PMID: 12578667
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2000 Dec;8(4):283-286.

To study the significance of calcium in the apoptosis of HL-60 cells induced by VP-16, the technology of flow cytometry, confocal laser scanning microscopy and Western blot were used. The results showed that VP-16 could induced the apoptosis of...

Activation of a Large-conductance Ca2+-Dependent K+ Channel by Stimulation of Glutamate Phosphoinositide-coupled Receptors in Cultured Cerebellar Granule Cells.

The European journal of neuroscience

Fagni L, Bossu JL, Bockaert J.
PMID: 12106464
Eur J Neurosci. 1991;3(8):778-789. doi: 10.1111/j.1460-9568.1991.tb01674.x.

Trans-1-amino-cyclopentyl-1,3-dicarboxylic acid (trans-ACPD), a specific agonist of the glutamate phosphoinositide-coupled receptor (Qp receptor), increased the amplitude of the outward K+ current recorded in the whole-cell configuration of the patch-clamp technique in mouse cultured cerebellar granule cells. This effect was...

Calcium-dependent release of adenosine and uridine nucleotides from A549 cells.

Purinergic signalling

Tatur S, Kreda S, Lazarowski E, Grygorczyk R.
PMID: 18368524
Purinergic Signal. 2008 Jun;4(2):139-46. doi: 10.1007/s11302-007-9059-x. Epub 2007 Jul 25.

Extracellular nucleotides play an important role in lung defense, but the release mechanism and relative abundance of different nucleotide species secreted by lung epithelia are not well defined. In this study, to minimize cell surface hydrolysis, we used a...

Evaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assay.

Journal of translational medicine

Shafer-Weaver KA, Sayers T, Kuhns DB, Strobl SL, Burkett MW, Baseler M, Malyguine A.
PMID: 15380049
J Transl Med. 2004 Sep 20;2(1):31. doi: 10.1186/1479-5876-2-31.

BACKGROUND: This study assessed the Granzyme B (GrB) ELISPOT as a viable alternative to the 51Cr-release assay for measuring cytotoxic activity of innate immune effector cells. We strategically selected the GrB ELISPOT assay because GrB is a hallmark effector...

Peptidoglycan Induces the Production of Interleukin-8 via Calcium Signaling in Human Gingival Epithelium.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Son A, Shin DM, Hong JH.
PMID: 25605997
Korean J Physiol Pharmacol. 2015 Jan;19(1):51-7. doi: 10.4196/kjpp.2015.19.1.51. Epub 2014 Dec 31.

The etiology of periodontal disease is multifactorial. Exogenous stimuli such as bacterial pathogens can interact with toll-like receptors to activate intracellular calcium signaling in gingival epithelium and other tissues. The triggering of calcium signaling induces the secretion of pro-inflammatory...

Methoxy-substituted tetrakisquinoline analogs of EGTA and BAPTA for fluorescence detection of Cd.

Dalton transactions (Cambridge, England : 2003)

Mikata Y, Kaneda M, Konno H, Matsumoto A, Sato SI, Kawamura M, Iwatsuki S.
PMID: 30698189
Dalton Trans. 2019 Mar 19;48(12):3840-3852. doi: 10.1039/c8dt04735a.

EGTA (ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid) and BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid) are well-known Ca2+ chelators that have four carboxylates, two nitrogen atoms and two ether oxygen atoms. In the present study, we prepared EGTQ (N,N,N',N'-tetrakis(2-quinolylmethyl)-1,2-bis(2-aminoethoxy)ethane) and BAPTQ (N,N,N',N'-tetrakis(2-quinolylmethyl)-1,2-bis(2-aminophenoxy)ethane) as quinoline...

Data on the concentrations of etoposide, PSC833, BAPTA-AM, and cycloheximide that do not compromise the vitality of mature mouse oocytes, parthenogencially activated and fertilized embryos.

Data in brief

Martin JH, Bromfield EG, Aitken RJ, Lord T, Nixon B.
PMID: 27547800
Data Brief. 2016 Jul 30;8:1215-20. doi: 10.1016/j.dib.2016.07.046. eCollection 2016 Sep.

These data document the vitality of mature mouse oocytes (Metaphase II (MII)) and early stage embryos (zygotes) following exposure to the genotoxic chemotherapeutic agent, etoposide, in combination with PSC833, a selective inhibitor of permeability glycoprotein. They also illustrate the...

Involvement of S1P1 receptor pathway in angiogenic effects of a novel adenosine-like nucleic acid analog COA-Cl in cultured human vascular endothelial cells.

Pharmacology research & perspectives

Igarashi J, Hashimoto T, Kubota Y, Shoji K, Maruyama T, Sakakibara N, Takuwa Y, Ujihara Y, Katanosaka Y, Mohri S, Naruse K, Yamashita T, Okamoto R, Hirano K, Kosaka H, Takata M, Konishi R, Tsukamoto I.
PMID: 25505610
Pharmacol Res Perspect. 2014 Oct;2(5):e00068. doi: 10.1002/prp2.68. Epub 2014 Aug 06.

COA-Cl (2Cl-C.OXT-A) is a recently developed adenosine-like nucleic acid analog that promotes angiogenesis via the mitogen-activated protein (MAP) kinases ERK1/2. Endothelial S1P1 receptor plays indispensable roles in developmental angiogenesis. In this study, we examined the functions of S1P1 in...

Relocalisation and activation of integrins induced rapidly by oestrogen via G-protein-coupled receptor 30 in mouse blastocysts.

Reproduction, fertility, and development

Qu T, Zhang SM, Yu LL, Zhang S, Yuan DZ, Xu Q, Zhang JH, He YP, Yue LM.
PMID: 25950704
Reprod Fertil Dev. 2015 May 08; doi: 10.1071/RD14227. Epub 2015 May 08.

Integrins are the dominant and final adhesion molecules in the attachment process between the blastocysts and endometrium. It is necessary for oestrogen to rapidly activate mouse blastocysts so that they attach to the endometrial epithelium. Our previous study suggested...

Calcium-loaded 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid blocks cell-to-cell diffusion of carboxyfluorescein in staminal hairs of Setcreasea purpurea.

Planta

Tucker EB.
PMID: 24196996
Planta. 1990 Aug;182(1):34-8. doi: 10.1007/BF00239980.

The effect of microinjected calcium-loaded 1,2-bis(2-aminophenoxy) ethane-N,N,N',N'-tetraacetic acid (CaBAPTA) on cell-to-cell diffusion of carboxyfluorescein (CF) was examined in staminal hairs of S. purpurea Boom. The CaBAPTA was microinjected into the cytoplasm of the staminal hairs either with CF or...

Showing 1 to 10 of 10 entries