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Development, factor structure and application of the Dog Obesity Risk and Appetite (DORA) questionnaire.

PeerJ

Raffan E, Smith SP, O'Rahilly S, Wardle J.
PMID: 26468435
PeerJ. 2015 Sep 29;3:e1278. doi: 10.7717/peerj.1278. eCollection 2015.

Background. Dogs are compelling models in which to study obesity since the condition shares many characteristics between humans and dogs. Differences in eating behaviour are recognised to contribute to obesity susceptibility in other species but this has not been...

Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells.

Molecular metabolism

Soedling H, Hodson DJ, Adrianssens AE, Gribble FM, Reimann F, Trapp S, Rutter GA.
PMID: 26413468
Mol Metab. 2015 Jun 25;4(9):619-30. doi: 10.1016/j.molmet.2015.06.007. eCollection 2015 Sep.

AIMS/HYPOTHESIS: The adipose tissue-derived hormone leptin plays an important role in the maintenance of body weight and glucose homeostasis. Leptin mediates its effects by interaction with leptin receptors (LepRb), which are highly expressed in the hypothalamus and other brain...

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain.

Molecular metabolism

Cork SC, Richards JE, Holt MK, Gribble FM, Reimann F, Trapp S.
PMID: 26500843
Mol Metab. 2015 Aug 05;4(10):718-31. doi: 10.1016/j.molmet.2015.07.008. eCollection 2015 Oct.

OBJECTIVE: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable. This study investigated the novel GLP-1R-Cre mouse as a...

SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.

Nature metabolism

Bidault G, Virtue S, Petkevicius K, Jolin HE, Dugourd A, Guénantin AC, Leggat J, Mahler-Araujo B, Lam BYH, Ma MK, Dale M, Carobbio S, Kaser A, Fallon PG, Saez-Rodriguez J, McKenzie ANJ, Vidal-Puig A.
PMID: 34531575
Nat Metab. 2021 Sep;3(9):1150-1162. doi: 10.1038/s42255-021-00440-5. Epub 2021 Sep 16.

Macrophages exhibit a spectrum of activation states ranging from classical to alternative activation

Showing 1 to 4 of 4 entries