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Germline whole exome sequencing and large-scale replication identifies .

Oncotarget

Dicks E, Song H, Ramus SJ, Oudenhove EV, Tyrer JP, Intermaggio MP, Kar S, Harrington P, Bowtell DD, Group AS, Cicek MS, Cunningham JM, Fridley BL, Alsop J, Jimenez-Linan M, Piskorz A, Goranova T, Kent E, Siddiqui N, Paul J, Crawford R, Poblete S, Lele S, Sucheston-Campbell L, Moysich KB, Sieh W, McGuire V, Lester J, Odunsi K, Whittemore AS, Bogdanova N, Dürst M, Hillemanns P, Karlan BY, Gentry-Maharaj A, Menon U, Tischkowitz M, Levine D, Brenton JD, Dörk T, Goode EL, Gayther SA, Pharoah DPP.
PMID: 28881617
Oncotarget. 2017 Mar 03;8(31):50930-50940. doi: 10.18632/oncotarget.15871. eCollection 2017 Aug 01.

We analyzed whole exome sequencing data in germline DNA from 412 high grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas Project and identified 5,517 genes harboring a predicted deleterious germline coding mutation in at least one...

Parenclitic networks for predicting ovarian cancer.

Oncotarget

Whitwell HJ, Blyuss O, Menon U, Timms JF, Zaikin A.
PMID: 29854310
Oncotarget. 2018 Apr 27;9(32):22717-22726. doi: 10.18632/oncotarget.25216. eCollection 2018 Apr 27.

Prediction and diagnosis of complex disease may not always be possible with a small number of biomarkers. Modern 'omics' technologies make it possible to cheaply and quantitatively assay hundreds of molecules generating large amounts of data from individual samples....

A quantitative performance study of two automatic methods for the diagnosis of ovarian cancer.

Biomedical signal processing and control

Vázquez MA, Mariño IP, Blyuss O, Ryan A, Gentry-Maharaj A, Kalsi J, Manchanda R, Jacobs I, Menon U, Zaikin A.
PMID: 30245736
Biomed Signal Process Control. 2018 Sep;46:86-93. doi: 10.1016/j.bspc.2018.07.001.

We present a quantitative study of the performance of two automatic methods for the early detection of ovarian cancer that can exploit longitudinal measurements of multiple biomarkers. The study is carried out for a subset of the data collected...

Showing 1 to 3 of 3 entries