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Engineering Escherichia coli for anaerobic alkane activation: Biosynthesis of (1-methylalkyl)succinates.

Biotechnology and bioengineering

Wang Y, Nguyen N, Lee SH, Wang Q, May JA, Gonzalez R, Cirino PC.
PMID: 34633065
Biotechnol Bioeng. 2022 Jan;119(1):315-320. doi: 10.1002/bit.27956. Epub 2021 Oct 16.

In anoxic environments, microbial activation of alkanes for subsequent metabolism occurs most commonly through the addition of fumarate to a subterminal carbon, producing an alkylsuccinate. Alkylsuccinate synthases are complex, multi-subunit enzymes that utilize a catalytic glycyl radical and require...

Cite
Wang Y, Nguyen N, Lee SH, et al. Engineering Escherichia coli for anaerobic alkane activation: Biosynthesis of (1-methylalkyl)succinates. Biotechnol Bioeng. 2021;119(1):315-320doi: 10.1002/bit.27956.
Wang, Y., Nguyen, N., Lee, S. H., Wang, Q., May, J. A., Gonzalez, R., & Cirino, P. C. (2022). Engineering Escherichia coli for anaerobic alkane activation: Biosynthesis of (1-methylalkyl)succinates. Biotechnology and bioengineering, 119(1), 315-320. https://doi.org/10.1002/bit.27956
Wang, Yixi, et al. "Engineering Escherichia coli for anaerobic alkane activation: Biosynthesis of (1-methylalkyl)succinates." Biotechnology and bioengineering vol. 119,1 (2022): 315-320. doi: https://doi.org/10.1002/bit.27956
Wang Y, Nguyen N, Lee SH, Wang Q, May JA, Gonzalez R, Cirino PC. Engineering Escherichia coli for anaerobic alkane activation: Biosynthesis of (1-methylalkyl)succinates. Biotechnol Bioeng. 2022 Jan;119(1):315-320. doi: 10.1002/bit.27956. Epub 2021 Oct 16. PMID: 34633065.
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