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Showing 1 to 12 of 13 entries
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Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity.

Parasites & vectors

Trienekens SCM, Faust CL, Besigye F, Pickering L, Tukahebwa EM, Seeley J, Lamberton PHL.
PMID: 34991702
Parasit Vectors. 2022 Jan 06;15(1):15. doi: 10.1186/s13071-021-05121-6.

BACKGROUND: Annual mass drug administration with praziquantel has reduced schistosomiasis transmission in some highly endemic areas, but areas with persistent high endemicity have been identified across sub-Saharan Africa, including Uganda. In these areas many children are rapidly reinfected post...

Variation in water contact behaviour and risk of Schistosoma mansoni (re)infection among Ugandan school-aged children in an area with persistent high endemicity.

Parasites & vectors

Trienekens SCM, Faust CL, Besigye F, Pickering L, Tukahebwa EM, Seeley J, Lamberton PHL.
PMID: 34991702
Parasit Vectors. 2022 Jan 06;15(1):15. doi: 10.1186/s13071-021-05121-6.

BACKGROUND: Annual mass drug administration with praziquantel has reduced schistosomiasis transmission in some highly endemic areas, but areas with persistent high endemicity have been identified across sub-Saharan Africa, including Uganda. In these areas many children are rapidly reinfected post...

Cellular metabolism and diseases.

British journal of pharmacology

Maiuri MC, Maffia P.
PMID: 33932230
Br J Pharmacol. 2021 May;178(10):2031-2033. doi: 10.1111/bph.15355.

LINKED ARTICLES: This article is part of a themed issue on Cellular metabolism and diseases. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v178.10/issuetoc.

ABO Blood Groups Do Not Predict .

Microorganisms

Francoeur R, Atuhaire A, Arinaitwe M, Adriko M, Ajambo D, Nankasi A, Babayan SA, Lamberton PHL.
PMID: 34946048
Microorganisms. 2021 Nov 27;9(12). doi: 10.3390/microorganisms9122448.

No abstract available.

High sodium intake, glomerular hyperfiltration, and protein catabolism in patients with essential hypertension.

Cardiovascular research

Rossitto G, Maiolino G, Lerco S, Ceolotto G, Blackburn G, Mary S, Antonelli G, Berton C, Bisogni V, Cesari M, Seccia TM, Lenzini L, Pinato A, Montezano A, Touyz RM, Petrie MC, Daly R, Welsh P, Plebani M, Rossi GP, Delles C.
PMID: 33053160
Cardiovasc Res. 2021 Apr 23;117(5):1372-1381. doi: 10.1093/cvr/cvaa205.

AIMS: A blood pressure (BP)-independent metabolic shift towards a catabolic state upon high sodium (Na+) diet, ultimately favouring body fluid preservation, has recently been described in pre-clinical controlled settings. We sought to investigate the real-life impact of high Na+...

ABO Blood Groups Do Not Predict .

Microorganisms

Francoeur R, Atuhaire A, Arinaitwe M, Adriko M, Ajambo D, Nankasi A, Babayan SA, Lamberton PHL.
PMID: 34946048
Microorganisms. 2021 Nov 27;9(12). doi: 10.3390/microorganisms9122448.

No abstract available.

Molecular imaging-The first visual themed issue published in the British Journal of Pharmacology.

British journal of pharmacology

Maffia P, Antoniades C, Ahluwalia A, Cirino G.
PMID: 34664273
Br J Pharmacol. 2021 Nov;178(21):4213-4215. doi: 10.1111/bph.15632.

No abstract available.

Molecular imaging of cardiovascular inflammation.

British journal of pharmacology

MacRitchie N, Noonan J, Guzik TJ, Maffia P.
PMID: 34378206
Br J Pharmacol. 2021 Nov;178(21):4216-4245. doi: 10.1111/bph.15654. Epub 2021 Oct 14.

Cardiovascular diseases (CVDs), including atherosclerosis, are chronic inflammatory diseases characterised by a complex and evolving tissue micro-environment. Molecular heterogeneity of inflammatory responses translates into clinical outcomes. However, current medical imaging modalities are unable to reveal the cellular and molecular...

Strategies for Reducing Non-Communicable Diseases in Africa.

Pharmacological research

Olowoyo P, Popoola F, Yaria J, Akinyemi R, Maffia P, Owolabi MO.
PMID: 34147659
Pharmacol Res. 2021 Aug;170:105736. doi: 10.1016/j.phrs.2021.105736. Epub 2021 Jun 17.

No abstract available.

Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function.

Cell death and differentiation

Campbell KJ, Mason SM, Winder ML, Willemsen RBE, Cloix C, Lawson H, Rooney N, Dhayade S, Sims AH, Blyth K, Tait SWG.
PMID: 33785871
Cell Death Differ. 2021 Sep;28(9):2589-2600. doi: 10.1038/s41418-021-00773-4. Epub 2021 Mar 31.

High levels of the anti-apoptotic BCL-2 family member MCL-1 are frequently found in breast cancer and, appropriately, BH3-mimetic drugs that specifically target MCL-1's function in apoptosis are in development as anti-cancer therapy. MCL-1 also has reported non-canonical roles that...

Degradation levels of continuous speech affect neural speech tracking and alpha power differently.

The European journal of neuroscience

Hauswald A, Keitel A, Chen YP, Rösch S, Weisz N.
PMID: 32687616
Eur J Neurosci. 2020 Jul 20; doi: 10.1111/ejn.14912. Epub 2020 Jul 20.

Making sense of a poor auditory signal can pose a challenge. Previous attempts to quantify speech intelligibility in neural terms have usually focused on one of two measures, namely low-frequency speech-brain synchronization or alpha power modulations. However, reports have...

Therapeutic targeting of inflammation in hypertension: from novel mechanisms to translational perspective.

Cardiovascular research

Murray EC, Nosalski R, MacRitchie N, Tomaszewski M, Maffia P, Harrison DG, Guzik TJ.
PMID: 34698811
Cardiovasc Res. 2021 Nov 22;117(13):2589-2609. doi: 10.1093/cvr/cvab330.

Both animal models and human observational and genetic studies have shown that immune and inflammatory mechanisms play a key role in hypertension and its complications. We review the effects of immunomodulatory interventions on blood pressure, target organ damage, and...

Showing 1 to 12 of 13 entries