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Showing 1 to 12 of 106 entries
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Utility of 5-alpha-reductase inhibitors in active surveillance for favourable risk prostate cancer.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Chiang AS, Loblaw DA, Jethava V, Sethukavalan P, Zhang L, Vesprini D, Mamedov A, Nam R, Klotz L.
PMID: 24381668
Can Urol Assoc J. 2013 Nov-Dec;7(11):450-3. doi: 10.5489/cuaj.262.

INTRODUCTION: This retrospective review compares prostate-specific antigen (PSA) doubling time (DT) prior to the initiation of a 5-alpha-reductase inhibitor (pre-5-ARI) to after the PSA nadir (post-nadir) has been reached for patients on active surveillance for favourable-risk prostate cancer.METHODS: Between...

The role of gonadotropin-releasing hormone antagonists for the treatment of benign prostatic hyperplasia.

Reviews in urology

Lepor H.
PMID: 17192797
Rev Urol. 2006;8(4):183-9.

Medical therapy is the preferred first-line approach in the management of lower urinary tract symptoms in men with benign prostatic hyperplasia. The magnitude of the improvement in lower urinary tract symptoms observed in response to combination therapy (alpha-blocker plus...

The medical therapy of prostatic symptoms study: what will we learn?.

Reviews in urology

Slawin KM.
PMID: 16985963
Rev Urol. 2003;5:S42-7.

Until recently, benign prostatic hyperplasia (BPH) was thought of as a relatively uncomplicated disease process resulting from age-related enlargement of the prostate gland, which was thought to cause all of the symptoms associated with the disease. Prostatectomy was considered...

5-alpha-Reductase Inhibitors Prevent the Progression of Benign Prostatic Hyperplasia.

Reviews in urology

Roehrborn CG.
PMID: 16985965
Rev Urol. 2003;5:S12-21.

Lower urinary tract symptoms (LUTS) associated with clinical benign prostatic hyperplasia (BPH) are a common occurrence in aging men, causing bother and interference with daily activities and affecting disease-specific quality of life. There is increasing evidence to suggest that,...

Efficacy and safety of 120-W GreenLight High-Performance System laser photo vaporization of the prostate: 3-year results with specific considerations.

Prostate international

Choi YS, Bae WJ, Kim SJ, Kim KS, Cho HJ, Hong SH, Lee JY, Hwang TK, Kim SW.
PMID: 24392442
Prostate Int. 2013;1(4):169-76. doi: 10.12954/PI.13030. Epub 2013 Dec 30.

PURPOSE: High-Performance System (HPS) laser photo vaporization of the prostate (PVP) is a widely used procedure nowadays. The safety and efficacy of the procedure has been affirmed in general patients with benign prostatic hyperplasia (BPH), but data on the...

[Medical therapy of lower urinary tract symptoms [corrected]].

Der Urologe. Ausg. A

Strittmatter F, Madersbacher S, Stief CG, Gratzke C.
PMID: 22782192
Urologe A. 2012 Aug;51(8):1125-36. doi: 10.1007/s00120-012-2943-1.

Male lower urinary tract symptoms (LUTS) include storage and voiding disorders and should be carefully evaluated before the start of any treatment. Medical therapy is directed at improving symptoms and reducing the risk of progression in order to improve...

Update on medical therapy for male LUTS.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Radomski SB.
PMID: 25243039
Can Urol Assoc J. 2014 Jul;8(7):S148-50. doi: 10.5489/cuaj.2310.

The medical management of lower urinary tract symptoms (LUTS) is aimed at addressing voiding and storage symptoms in patients with benign prostate hyperplasia (BPH) symptoms with or without an over-active bladder (OAB). Current available options for BPH include alpha-blockers,...

Prostate Cancer Risk and Prognostic Influence Among Users of 5-Alpha-Reductase Inhibitors and Alpha-Blockers: A Systematic Review and Meta-Analysis.

Urology

Wu Y, Wang Y, Gu Y, Xia J, Qian Q, Hong Y.
PMID: 32745485
Urology. 2020 Nov;145:216-223. doi: 10.1016/j.urology.2020.05.105. Epub 2020 Jul 31.

We systematically assessed the effect of 5-alpha-reductase inhibitors (5-ARIs) and/or alpha-blockers use on prostate cancer (CaP) incidence and outcomes, including CaP pathologic progression, CaP-specific mortality, and all-cause mortality. 5-ARIs but not alpha-blockers decreased risk of overall CaP, low grade...

The Risk of Venous Thromboembolism (VTE) in Men with Benign Prostatic Hyperplasia Treated with 5-Alpha Reductase Inhibitors (5ARIs).

Clinical epidemiology

Ayodele O, Cabral HJ, McManus D, Jick S.
PMID: 34377032
Clin Epidemiol. 2021 Aug 03;13:661-673. doi: 10.2147/CLEP.S317019. eCollection 2021.

BACKGROUND: Many men receive 5-alpha reductase inhibitors (5ARIs) for ongoing treatment of benign prostatic hyperplasia (BPH). The increased risk of cardiovascular complications with 5ARIs has been documented in BPH studies and the occurrence of cerebral venous thrombosis, presumably due...

Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin.

The International journal of risk & safety in medicine

Healy D, Bahrick A, Bak M, Barbato A, Calabrò RS, Chubak BM, Cosci F, Csoka AB, D'Avanzo B, Diviccaro S, Giatti S, Goldstein I, Graf H, Hellstrom WJG, Irwig MS, Jannini EA, Janssen PKC, Khera M, Kumar MT, Le Noury J, Lew-Starowicz M, Linden DEJ, Lüning C, Mangin D, Melcangi RC, Rodríguez OWMAAS, Panicker JN, Patacchini A, Pearlman AM, Pukall CF, Raj S, Reisman Y, Rubin RS, Schreiber R, Shipko S, Vašečková B, Waraich A.
PMID: 34719438
Int J Risk Saf Med. 2021 Oct 26; doi: 10.3233/JRS-210023. Epub 2021 Oct 26.

BACKGROUND: A set of enduring conditions have been reported in the literature involving persistent sexual dysfunction after discontinuation of serotonin reuptake inhibiting antidepressants, 5 alpha-reductase inhibitors and isotretinoin.OBJECTIVE: To develop diagnostic criteria for post-SSRI sexual dysfunction (PSSD), persistent genital...

Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors - dutasteride and finasteride - in the presence of testosterone.

Singapore medical journal

Hatanaka T, Lulic Z, Mefo T, Booth C, Harrison E, Ong G.
PMID: 34157805
Singapore Med J. 2021 Jun 22; doi: 10.11622/smedj.2021080. Epub 2021 Jun 22.

No abstract available.

Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial (EAT-DUTA AndroCoV Trial - Biochemical).

Cureus

Cadegiani FA, McCoy J, Gustavo Wambier C, Goren A.
PMID: 33643746
Cureus. 2021 Feb 01;13(2):e13047. doi: 10.7759/cureus.13047.

Background and objective Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry and subsequent infectivity are mediated by androgens and the androgen receptors through the regulation of transmembrane protease, serine 2 (TMPRSS2). Androgenetic alopecia (AGA) predisposes males to severe...

Showing 1 to 12 of 106 entries