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Showing 1 to 4 of 4 entries
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Colonic inflammation induces changes in glucose levels through modulation of incretin system.

Pharmacological reports : PR

Zatorski H, Salaga M, Zielińska M, Mokrowiecka A, Jacenik D, Krajewska WM, Małecka-Panas E, Fichna J.
PMID: 34535873
Pharmacol Rep. 2021 Dec;73(6):1670-1679. doi: 10.1007/s43440-021-00327-y. Epub 2021 Sep 17.

BACKGROUND: The role of the incretin hormone, glucagon-like peptide (GLP-1), in Crohn's disease (CD), is still poorly understood. The aim of this study was to investigate whether colitis is associated with changes in blood glucose levels and the possible...

Blockade of fructose transporter protein GLUT5 inhibits proliferation of colon cancer cells: proof of concept for a new class of anti-tumor therapeutics.

Pharmacological reports : PR

Włodarczyk J, Włodarczyk M, Zielińska M, Jędrzejczak B, Dziki Ł, Fichna J.
PMID: 34052986
Pharmacol Rep. 2021 Jun;73(3):939-945. doi: 10.1007/s43440-021-00281-9. Epub 2021 May 29.

BACKGROUND: Despite the fact that colorectal cancer (CRC) is one of the most commonly diagnosed cancers in men and women, its current treatment remains unsatisfactory and therefore novel studies proposing new approaches are necessary. A high sugar diet is...

IBS-Symptoms in IBD Patients-Manifestation of Concomitant or Different Entities.

Journal of clinical medicine

Szałwińska P, Włodarczyk J, Spinelli A, Fichna J, Włodarczyk M.
PMID: 33374388
J Clin Med. 2020 Dec 24;10(1). doi: 10.3390/jcm10010031.

Irritable bowel syndrome (IBS) is a functional heterogenous disease with a multifactorial pathogenesis. It is characterized by abdominal pain, discomfort, and alteration in gut motility. The occurrence of similar symptoms was observed in patients in clinical remission of inflammatory...

Chlorogenic acid reduces inflammation in murine model of acute pancreatitis.

Pharmacological reports : PR

Tarasiuk A, Bulak K, Talar M, Fichna J.
PMID: 34383255
Pharmacol Rep. 2021 Oct;73(5):1448-1456. doi: 10.1007/s43440-021-00320-5. Epub 2021 Aug 12.

BACKGROUND: The pathogenesis of acute pancreatitis (AP) initiation and progression is still unknown, and effective treatment is limited to supportive care. Many phytochemicals have the potential to alleviate AP symptoms and may be a useful and effective supplement to...

Showing 1 to 4 of 4 entries