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Showing 1 to 12 of 36 entries
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Urine creatinine concentration and clinical outcomes in older adults: The Cardiovascular Health Study.

Journal of the American Geriatrics Society

Barzilay JI, Buzkova P, Shlipak MG, Lyles MF, Bansal N, Garimella PS, Ix JH, Kizer JR, Strotmeyer ES, Djousse L, Biggs ML, Siscovick D, Mukamal KJ.
PMID: 34363689
J Am Geriatr Soc. 2021 Dec;69(12):3486-3496. doi: 10.1111/jgs.17388. Epub 2021 Aug 07.

PURPOSE: Loss of muscle mass and strength are associated with long-term adverse health outcomes in older adults. Urine creatinine concentrations (Ucr; mg/dl) are a measure of muscle tissue mass and turnover. This study assessed the associations of a spot...

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Barzilay JI, Buzkova P, Shlipak MG, et al. Urine creatinine concentration and clinical outcomes in older adults: The Cardiovascular Health Study. J Am Geriatr Soc. 2021;69(12):3486-3496doi: 10.1111/jgs.17388.
Barzilay, J. I., Buzkova, P., Shlipak, M. G., Lyles, M. F., Bansal, N., Garimella, P. S., Ix, J. H., Kizer, J. R., Strotmeyer, E. S., Djousse, L., Biggs, M. L., Siscovick, D., & Mukamal, K. J. (2021). Urine creatinine concentration and clinical outcomes in older adults: The Cardiovascular Health Study. Journal of the American Geriatrics Society, 69(12), 3486-3496. https://doi.org/10.1111/jgs.17388
Barzilay, Joshua I, et al. "Urine creatinine concentration and clinical outcomes in older adults: The Cardiovascular Health Study." Journal of the American Geriatrics Society vol. 69,12 (2021): 3486-3496. doi: https://doi.org/10.1111/jgs.17388
Barzilay JI, Buzkova P, Shlipak MG, Lyles MF, Bansal N, Garimella PS, Ix JH, Kizer JR, Strotmeyer ES, Djousse L, Biggs ML, Siscovick D, Mukamal KJ. Urine creatinine concentration and clinical outcomes in older adults: The Cardiovascular Health Study. J Am Geriatr Soc. 2021 Dec;69(12):3486-3496. doi: 10.1111/jgs.17388. Epub 2021 Aug 07. PMID: 34363689; PMCID: PMC8648977.
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Serum Nonesterified Fatty Acids and Incident Stroke: The CHS.

Journal of the American Heart Association

Huang NK, Biggs ML, Matthan NR, Djoussé L, Longstreth WT, Mukamal KJ, Siscovick DS, Lichtenstein AH.
PMID: 34755529
J Am Heart Assoc. 2021 Nov 16;10(22):e022725. doi: 10.1161/JAHA.121.022725. Epub 2021 Nov 10.

Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies. We evaluated the associations between incident stroke and serum concentrations of nonesterified saturated, monounsaturated, polyunsaturated, and

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Huang NK, Biggs ML, Matthan NR, et al. Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. J Am Heart Assoc. 2021;10(22):e022725doi: 10.1161/JAHA.121.022725.
Huang, N. K., Biggs, M. L., Matthan, N. R., Djoussé, L., Longstreth, W. T., Mukamal, K. J., Siscovick, D. S., & Lichtenstein, A. H. (2021). Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. Journal of the American Heart Association, 10(22), e022725. https://doi.org/10.1161/JAHA.121.022725
Huang, Neil K, et al. "Serum Nonesterified Fatty Acids and Incident Stroke: The CHS." Journal of the American Heart Association vol. 10,22 (2021): e022725. doi: https://doi.org/10.1161/JAHA.121.022725
Huang NK, Biggs ML, Matthan NR, Djoussé L, Longstreth WT, Mukamal KJ, Siscovick DS, Lichtenstein AH. Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. J Am Heart Assoc. 2021 Nov 16;10(22):e022725. doi: 10.1161/JAHA.121.022725. Epub 2021 Nov 10. PMID: 34755529.
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Serum Nonesterified Fatty Acids and Incident Stroke: The CHS.

Journal of the American Heart Association

Huang NK, Biggs ML, Matthan NR, Djoussé L, Longstreth WT, Mukamal KJ, Siscovick DS, Lichtenstein AH.
PMID: 34755529
J Am Heart Assoc. 2021 Nov 16;10(22):e022725. doi: 10.1161/JAHA.121.022725. Epub 2021 Nov 10.

Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies. We evaluated the associations between incident stroke and serum concentrations of nonesterified saturated, monounsaturated, polyunsaturated, and

Cite
Huang NK, Biggs ML, Matthan NR, et al. Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. J Am Heart Assoc. 2021;10(22):e022725doi: 10.1161/JAHA.121.022725.
Huang, N. K., Biggs, M. L., Matthan, N. R., Djoussé, L., Longstreth, W. T., Mukamal, K. J., Siscovick, D. S., & Lichtenstein, A. H. (2021). Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. Journal of the American Heart Association, 10(22), e022725. https://doi.org/10.1161/JAHA.121.022725
Huang, Neil K, et al. "Serum Nonesterified Fatty Acids and Incident Stroke: The CHS." Journal of the American Heart Association vol. 10,22 (2021): e022725. doi: https://doi.org/10.1161/JAHA.121.022725
Huang NK, Biggs ML, Matthan NR, Djoussé L, Longstreth WT, Mukamal KJ, Siscovick DS, Lichtenstein AH. Serum Nonesterified Fatty Acids and Incident Stroke: The CHS. J Am Heart Assoc. 2021 Nov 16;10(22):e022725. doi: 10.1161/JAHA.121.022725. Epub 2021 Nov 10. PMID: 34755529; PMCID: PMC8751910.
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Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study.

Chest

Anderson MR, Kim JS, Allison M, Giles JT, Hoffman EA, Ding J, Barr RG, Podolanczuk A.
PMID: 33844978
Chest. 2021 Aug;160(2):582-594. doi: 10.1016/j.chest.2021.03.058. Epub 2021 Apr 15.

BACKGROUND: Obesity is associated with restrictive ventilatory defects and a faster rate of decline in FVC. This association is not exclusively mediated by mechanical factors and may reflect direct pulmonary injury by adipose-derived mediators.RESEARCH QUESTION: Is adipose tissue involved...

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Anderson MR, Kim JS, Allison M, et al. Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study. Chest. 2021;160(2):582-594doi: 10.1016/j.chest.2021.03.058.
Anderson, M. R., Kim, J. S., Allison, M., Giles, J. T., Hoffman, E. A., Ding, J., Barr, R. G., & Podolanczuk, A. (2021). Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study. Chest, 160(2), 582-594. https://doi.org/10.1016/j.chest.2021.03.058
Anderson, Michaela R, et al. "Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study." Chest vol. 160,2 (2021): 582-594. doi: https://doi.org/10.1016/j.chest.2021.03.058
Anderson MR, Kim JS, Allison M, Giles JT, Hoffman EA, Ding J, Barr RG, Podolanczuk A. Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study. Chest. 2021 Aug;160(2):582-594. doi: 10.1016/j.chest.2021.03.058. Epub 2021 Apr 15. PMID: 33844978; PMCID: PMC8411451.
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Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome.

EBioMedicine

Zeng Y, Amador C, Gao C, Walker RM, Morris SW, Campbell A, Frkatović A, Madden RA, Adams MJ, He S, Bretherick AD, Hayward C, Porteous DJ, Wilson JF, Evans KL, McIntosh AM, Navarro P, Haley CS.
PMID: 34883445
EBioMedicine. 2021 Dec 05;74:103730. doi: 10.1016/j.ebiom.2021.103730. Epub 2021 Dec 05.

BACKGROUND: parent-of-origin effects (POE) play important roles in complex disease and thus understanding their regulation and associated molecular and phenotypic variation are warranted. Previous studies mainly focused on the detection of genomic regions or phenotypes regulated by POE. Understanding...

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Zeng Y, Amador C, Gao C, et al. Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome. EBioMedicine. 2021;74:103730doi: 10.1016/j.ebiom.2021.103730.
Zeng, Y., Amador, C., Gao, C., Walker, R. M., Morris, S. W., Campbell, A., Frkatović, A., Madden, R. A., Adams, M. J., He, S., Bretherick, A. D., Hayward, C., Porteous, D. J., Wilson, J. F., Evans, K. L., McIntosh, A. M., Navarro, P., & Haley, C. S. (2021). Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome. EBioMedicine, 74103730. https://doi.org/10.1016/j.ebiom.2021.103730
Zeng, Yanni, et al. "Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome." EBioMedicine vol. 74 (2021): 103730. doi: https://doi.org/10.1016/j.ebiom.2021.103730
Zeng Y, Amador C, Gao C, Walker RM, Morris SW, Campbell A, Frkatović A, Madden RA, Adams MJ, He S, Bretherick AD, Hayward C, Porteous DJ, Wilson JF, Evans KL, McIntosh AM, Navarro P, Haley CS. Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome. EBioMedicine. 2021 Dec 05;74:103730. doi: 10.1016/j.ebiom.2021.103730. Epub 2021 Dec 05. PMID: 34883445; PMCID: PMC8654798.
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Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study.

Chest

Anderson MR, Kim JS, Allison M, Giles JT, Hoffman EA, Ding J, Barr RG, Podolanczuk A.
PMID: 33844978
Chest. 2021 Aug;160(2):582-594. doi: 10.1016/j.chest.2021.03.058. Epub 2021 Apr 15.

BACKGROUND: Obesity is associated with restrictive ventilatory defects and a faster rate of decline in FVC. This association is not exclusively mediated by mechanical factors and may reflect direct pulmonary injury by adipose-derived mediators.RESEARCH QUESTION: Is adipose tissue involved...

Cite
Anderson MR, Kim JS, Allison M, et al. Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study. Chest. 2021;160(2):582-594doi: 10.1016/j.chest.2021.03.058.
Anderson, M. R., Kim, J. S., Allison, M., Giles, J. T., Hoffman, E. A., Ding, J., Barr, R. G., & Podolanczuk, A. (2021). Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study. Chest, 160(2), 582-594. https://doi.org/10.1016/j.chest.2021.03.058
Anderson, Michaela R, et al. "Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study." Chest vol. 160,2 (2021): 582-594. doi: https://doi.org/10.1016/j.chest.2021.03.058
Anderson MR, Kim JS, Allison M, Giles JT, Hoffman EA, Ding J, Barr RG, Podolanczuk A. Adiposity and Interstitial Lung Abnormalities in Community-Dwelling Adults: The MESA Cohort Study. Chest. 2021 Aug;160(2):582-594. doi: 10.1016/j.chest.2021.03.058. Epub 2021 Apr 15. PMID: 33844978; PMCID: PMC8411451.
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Reproducibility of global electrical heterogeneity measurements on 12-lead ECG: The Multi-Ethnic Study of Atherosclerosis.

Journal of electrocardiology

Haq KT, Lutz KJ, Peters KK, Craig NE, Mitchell E, Desai AK, Stencel NWL, Soliman EZ, Lima JAC, Tereshchenko LG.
PMID: 34626835
J Electrocardiol. 2021 Nov-Dec;69:96-104. doi: 10.1016/j.jelectrocard.2021.09.014. Epub 2021 Oct 02.

OBJECTIVE: Vectorcardiographic (VCG) global electrical heterogeneity (GEH) metrics showed clinical usefulness. We aimed to assess the reproducibility of GEH metrics.METHODS: GEH was measured on two 10-s 12‑lead ECGs recorded on the same day in 4316 participants of the Multi-Ethnic...

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Haq KT, Lutz KJ, Peters KK, et al. Reproducibility of global electrical heterogeneity measurements on 12-lead ECG: The Multi-Ethnic Study of Atherosclerosis. J Electrocardiol. 2021;69:96-104doi: 10.1016/j.jelectrocard.2021.09.014.
Haq, K. T., Lutz, K. J., Peters, K. K., Craig, N. E., Mitchell, E., Desai, A. K., Stencel, N. W. L., Soliman, E. Z., Lima, J. A. C., & Tereshchenko, L. G. (2021). Reproducibility of global electrical heterogeneity measurements on 12-lead ECG: The Multi-Ethnic Study of Atherosclerosis. Journal of electrocardiology, 6996-104. https://doi.org/10.1016/j.jelectrocard.2021.09.014
Haq, Kazi T, et al. "Reproducibility of global electrical heterogeneity measurements on 12-lead ECG: The Multi-Ethnic Study of Atherosclerosis." Journal of electrocardiology vol. 69 (2021): 96-104. doi: https://doi.org/10.1016/j.jelectrocard.2021.09.014
Haq KT, Lutz KJ, Peters KK, Craig NE, Mitchell E, Desai AK, Stencel NWL, Soliman EZ, Lima JAC, Tereshchenko LG. Reproducibility of global electrical heterogeneity measurements on 12-lead ECG: The Multi-Ethnic Study of Atherosclerosis. J Electrocardiol. 2021 Nov-Dec;69:96-104. doi: 10.1016/j.jelectrocard.2021.09.014. Epub 2021 Oct 02. PMID: 34626835; PMCID: PMC8627471.
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Longitudinal associations between objective and perceived healthy food environment and diet: The Multi-Ethnic Study of Atherosclerosis.

Social science & medicine (1982)

Gao X, Engeda J, Moore LV, Auchincloss AH, Moore K, Mujahid MS.
PMID: 34802783
Soc Sci Med. 2022 Jan;292:114542. doi: 10.1016/j.socscimed.2021.114542. Epub 2021 Nov 06.

INTRODUCTION: Research examining the influence of neighborhood healthy food environment on diet has been mostly cross-sectional and has lacked robust characterization of the food environment. We examined longitudinal associations between features of the local food environment and healthy diet,...

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Gao X, Engeda J, Moore LV, et al. Longitudinal associations between objective and perceived healthy food environment and diet: The Multi-Ethnic Study of Atherosclerosis. Soc Sci Med. 2021;292:114542doi: 10.1016/j.socscimed.2021.114542.
Gao, X., Engeda, J., Moore, L. V., Auchincloss, A. H., Moore, K., & Mujahid, M. S. (2022). Longitudinal associations between objective and perceived healthy food environment and diet: The Multi-Ethnic Study of Atherosclerosis. Social science & medicine (1982), 292114542. https://doi.org/10.1016/j.socscimed.2021.114542
Gao, Xing, et al. "Longitudinal associations between objective and perceived healthy food environment and diet: The Multi-Ethnic Study of Atherosclerosis." Social science & medicine (1982) vol. 292 (2022): 114542. doi: https://doi.org/10.1016/j.socscimed.2021.114542
Gao X, Engeda J, Moore LV, Auchincloss AH, Moore K, Mujahid MS. Longitudinal associations between objective and perceived healthy food environment and diet: The Multi-Ethnic Study of Atherosclerosis. Soc Sci Med. 2022 Jan;292:114542. doi: 10.1016/j.socscimed.2021.114542. Epub 2021 Nov 06. PMID: 34802783; PMCID: PMC8748383.
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Cardiac mechanics and incident ischemic stroke: the Cardiovascular Health Study.

Scientific reports

Kamel H, Bartz TM, Longstreth WT, Elkind MSV, Gottdiener J, Kizer JR, Gardin JM, Kim J, Shah S.
PMID: 34462469
Sci Rep. 2021 Aug 30;11(1):17358. doi: 10.1038/s41598-021-96702-z.

Recent evidence indicates that our understanding of the relationship between cardiac function and ischemic stroke remains incomplete. The Cardiovascular Health Study enrolled community-dwelling adults ≥ 65 years old. We included participants with speckle-tracking data from digitized baseline study echocardiograms....

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Kamel H, Bartz TM, Longstreth WT, et al. Cardiac mechanics and incident ischemic stroke: the Cardiovascular Health Study. Sci Rep. 2021;11(1):17358doi: 10.1038/s41598-021-96702-z.
Kamel, H., Bartz, T. M., Longstreth, W. T., Elkind, M. S. V., Gottdiener, J., Kizer, J. R., Gardin, J. M., Kim, J., & Shah, S. (2021). Cardiac mechanics and incident ischemic stroke: the Cardiovascular Health Study. Scientific reports, 11(1), 17358. https://doi.org/10.1038/s41598-021-96702-z
Kamel, Hooman, et al. "Cardiac mechanics and incident ischemic stroke: the Cardiovascular Health Study." Scientific reports vol. 11,1 (2021): 17358. doi: https://doi.org/10.1038/s41598-021-96702-z
Kamel H, Bartz TM, Longstreth WT, Elkind MSV, Gottdiener J, Kizer JR, Gardin JM, Kim J, Shah S. Cardiac mechanics and incident ischemic stroke: the Cardiovascular Health Study. Sci Rep. 2021 Aug 30;11(1):17358. doi: 10.1038/s41598-021-96702-z. PMID: 34462469; PMCID: PMC8405795.
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Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses.

The lancet. Diabetes & endocrinology

[No authors listed]
PMID: 34717822
Lancet Diabetes Endocrinol. 2021 Dec;9(12):837-846. doi: 10.1016/S2213-8587(21)00263-1. Epub 2021 Oct 28.

BACKGROUND: Randomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. However, generalisability of results to individuals with low vitamin D status is unclear. We aimed to characterise dose-response relationships between 25-hydroxyvitamin...

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Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. Lancet Diabetes Endocrinol. 2021;9(12):837-846doi: 10.1016/S2213-8587(21)00263-1.
(2021). Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. The lancet. Diabetes & endocrinology, 9(12), 837-846. https://doi.org/10.1016/S2213-8587(21)00263-1
"Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses." The lancet. Diabetes & endocrinology vol. 9,12 (2021): 837-846. doi: https://doi.org/10.1016/S2213-8587(21)00263-1
Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses. Lancet Diabetes Endocrinol. 2021 Dec;9(12):837-846. doi: 10.1016/S2213-8587(21)00263-1. Epub 2021 Oct 28. PMID: 34717822; PMCID: PMC8600124.
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Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetes.

Journal of lipid research

Fretts AM, Jensen PN, Hoofnagle AN, McKnight B, Howard BV, Umans J, Sitlani CM, Siscovick DS, King IB, Djousse L, Sotoodehnia N, Lemaitre RN.
PMID: 34555371
J Lipid Res. 2021;62:100119. doi: 10.1016/j.jlr.2021.100119. Epub 2021 Sep 20.

Recent studies suggest that the type of saturated fatty acid bound to sphingolipids influences the biological activity of those sphingolipids. However, it is unknown whether associations of sphingolipids with diabetes may differ by the identity of bound lipid species....

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Fretts AM, Jensen PN, Hoofnagle AN, et al. Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetes. J Lipid Res. 2021;62:100119doi: 10.1016/j.jlr.2021.100119.
Fretts, A. M., Jensen, P. N., Hoofnagle, A. N., McKnight, B., Howard, B. V., Umans, J., Sitlani, C. M., Siscovick, D. S., King, I. B., Djousse, L., Sotoodehnia, N., & Lemaitre, R. N. (2021). Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetes. Journal of lipid research, 62100119. https://doi.org/10.1016/j.jlr.2021.100119
Fretts, Amanda M, et al. "Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetes." Journal of lipid research vol. 62 (2021): 100119. doi: https://doi.org/10.1016/j.jlr.2021.100119
Fretts AM, Jensen PN, Hoofnagle AN, McKnight B, Howard BV, Umans J, Sitlani CM, Siscovick DS, King IB, Djousse L, Sotoodehnia N, Lemaitre RN. Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetes. J Lipid Res. 2021;62:100119. doi: 10.1016/j.jlr.2021.100119. Epub 2021 Sep 20. PMID: 34555371; PMCID: PMC8517199.
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Cumulative burden of clinically significant aortic stenosis in community-dwelling older adults.

Heart (British Cardiac Society)

Owens DS, Bartz TM, Buzkova P, Massera D, Biggs ML, Carlson SD, Psaty BM, Sotoodehnia N, Gottdiener JS, Kizer JR.
PMID: 34083406
Heart. 2021 Sep;107(18):1493-1502. doi: 10.1136/heartjnl-2021-319025. Epub 2021 Jun 02.

OBJECTIVES: Current estimates of aortic stenosis (AS) frequency have mostly relied on cross-sectional echocardiographic or longitudinal administrative data, making understanding of AS burden incomplete. We performed case adjudications to evaluate the frequency of AS and assess differences by age,...

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Owens DS, Bartz TM, Buzkova P, et al. Cumulative burden of clinically significant aortic stenosis in community-dwelling older adults. Heart. 2021;107(18):1493-1502doi: 10.1136/heartjnl-2021-319025.
Owens, D. S., Bartz, T. M., Buzkova, P., Massera, D., Biggs, M. L., Carlson, S. D., Psaty, B. M., Sotoodehnia, N., Gottdiener, J. S., & Kizer, J. R. (2021). Cumulative burden of clinically significant aortic stenosis in community-dwelling older adults. Heart (British Cardiac Society), 107(18), 1493-1502. https://doi.org/10.1136/heartjnl-2021-319025
Owens, David S, et al. "Cumulative burden of clinically significant aortic stenosis in community-dwelling older adults." Heart (British Cardiac Society) vol. 107,18 (2021): 1493-1502. doi: https://doi.org/10.1136/heartjnl-2021-319025
Owens DS, Bartz TM, Buzkova P, Massera D, Biggs ML, Carlson SD, Psaty BM, Sotoodehnia N, Gottdiener JS, Kizer JR. Cumulative burden of clinically significant aortic stenosis in community-dwelling older adults. Heart. 2021 Sep;107(18):1493-1502. doi: 10.1136/heartjnl-2021-319025. Epub 2021 Jun 02. PMID: 34083406.
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