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Showing 1 to 7 of 7 entries
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Adenosine receptor and beta-adrenoceptor stimulation increases noradrenaline synthesis in hippocampal synaptosomes.

Neurochemistry international

Birch PJ, Fillenz M.
PMID: 20493043
Neurochem Int. 1986;8(2):165-70. doi: 10.1016/0197-0186(86)90160-9.

The synthesis of noradrenaline was measured, using high-performance liquid chromatography with electrochemical detection, in synaptosomal fractions prepared from rat hippocampus. Noradrenaline synthesis is depressed by adenosine deaminase and the adenosine antagonist, 8-phenyltheophylline and stimulated by the adenosine agonist, 2-chloroadenosine....

Involvement of adenosine receptors in mouse thermoregulation.

Journal of psychopharmacology (Oxford, England)

Zarrindast MR, Heidari MR.
PMID: 22291000
J Psychopharmacol. 1993 Jan;7(4):365-70. doi: 10.1177/026988119300700408.

The effects of the activation of adenosine receptors on core body temperature of mice have been studied in the present investigation. Intraperitoneal (i.p.) injection of non-selective adenosine agonists 5'-N ethyl- carboxamide adenosine (NECA; 0.001, 0.01 and 0.05 mg/kg), R-(N(6)-phenylisopropyl)-adenosine...

[(3)H]Glycogen hydrolysis elicited by adenosine in rabbit retina: involvement of A(2)-receptors.

Neurochemistry international

Osborne NN.
PMID: 20504444
Neurochem Int. 1989;14(4):419-22. doi: 10.1016/0197-0186(89)90030-2.

Adenosine promotes a concentration-dependent hydrolysis of [(3)H]glycogen newly synthesised from [(3)H]glucose by rabbit retinal slices. The EC(50) is 15 ?M. Theophylline and 8-phenyltheophylline antagonise the glycogenolysis induced by adenosine. The rank order of efficacy of adenosine agonists is chloroadenosine...

Degranulation of rat omental mast cells by A(1) receptor agonists in vitro.

Mediators of inflammation

Northover AM, Northover BJ.
PMID: 18475728
Mediators Inflamm. 1996;5(5):341-5. doi: 10.1155/S096293519600049X.

The haemodynamic effects of adenosine are thought to result in part from a release of mast cell amines via A3 receptor stimulation. To investigate the nature of the receptors involved in adenosine-induced mast cell degranulation in the rat isolated...

Bronchospasmolytic and Adenosine Binding Activity of 8- (Proline / Pyrazole)- Substituted Xanthine Derivatives.

Current drug discovery technologies

Singh S, Ojha M, Yadav D, Kachler S, Klotz KN, Yadav R.
PMID: 32962622
Curr Drug Discov Technol. 2021;18(5):e22092020186181. doi: 10.2174/1570163817666200922121005.

BACKGROUND: 8-Phenyltheophylline derivatives exhibit prophylactic effects at a specific dose but do not produce the cardiovascular or emetic side effects associated with xanthines, thereby exhibiting unique characteristics of potential therapeutic importance.METHODS: Novel series of 8-(proline/pyrazole)-substituted xanthine analogs have been...

The role of ATP and adenosine in the control of hepatic blood flow in the rabbit liver in vivo.

Comparative hepatology

Browse DJ, Mathie RT, Benjamin IS, Alexander B.
PMID: 14641917
Comp Hepatol. 2003 Nov 26;2(1):9. doi: 10.1186/1476-5926-2-9.

BACKGROUND: The role of adenosine and ATP in the regulation of hepatic arterial blood flow in the "buffer response" was studied in vitro and in a new in vivo model in the rabbit. The model achieves portal-systemic diversion by...

Mast cell amines and inosineinduced vasoconstriction in the rat hind limb.

Mediators of inflammation

Northover AM, Northover BJ.
PMID: 18472848
Mediators Inflamm. 1997;6(2):141-5. doi: 10.1080/09629359791848.

Under certain circumstances injected inosine causes a net vasoconstrictive effect on the arterioles, which has been attributed to 5-hydroxytryptamine (5HT) released in response to adenosine type 3 (A(3)) receptor stimulation of mast cells residing in the adventitia. We have...

Showing 1 to 7 of 7 entries