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Showing 1 to 12 of 84 entries
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Apixaban and oral implications.

Journal of clinical and experimental dentistry

Lopez-Galindo M, Bagán JV.
PMID: 26535102
J Clin Exp Dent. 2015 Oct 01;7(4):e528-34. doi: 10.4317/jced.52470. eCollection 2015 Oct.

BACKGROUND: Thrombotic disorders remain a leading cause of death in the Western world, and in this regard a number of anticoagulation treatment have been used, including heparins, fondaparinux, vitamin K antagonists (warfarin, acenocoumarol), and new oral anticoagulants such as...

Spontaneous epidural hematoma of the spine associated with oral anticoagulants: 3 Case Studies.

International journal of surgery case reports

Tawk C, El Hajj Moussa M, Zgheib R, Nohra G.
PMID: 26074484
Int J Surg Case Rep. 2015;13:8-11. doi: 10.1016/j.ijscr.2015.05.022. Epub 2015 May 29.

INTRODUCTION: Spontaneous epidural hematoma of the spine (SEHS) is an extremely rare entity. Patients known to have thrombophilia or on anticoagulant drugs are the most affected. It is generally caused by a rupture of the postero-internal vertebral venous plexus...

A Systematic Literature Review on the Cost-Effectiveness of Apixaban for Stroke Prevention in Non-valvular Atrial Fibrillation.

Cardiology and therapy

Pinyol C, Cepeda JM, Roldan I, Roldan V, Jimenez S, Gonzalez P, Soto J.
PMID: 27457613
Cardiol Ther. 2016 Dec;5(2):171-186. doi: 10.1007/s40119-016-0066-2. Epub 2016 Jul 25.

INTRODUCTION: Economic evaluations are becoming increasingly important due to limitations in economic resources, the expense of many new treatments, the need to allocate health spending as effectively as possible, and the need to inform decision makers. Based on the...

Severe rhabdomyolysis secondary to simvastatin and acenocoumarol.

European journal of internal medicine

Salinas A, Solís J, Rico LA.
PMID: 17338976
Eur J Intern Med. 2007 Mar;18(2):165. doi: 10.1016/j.ejim.2006.07.030.

No abstract available.

Interactions between Natural Health Products and Oral Anticoagulants: Spontaneous Reports in the Italian Surveillance System of Natural Health Products.

Evidence-based complementary and alternative medicine : eCAM

Paoletti A, Gallo E, Benemei S, Vietri M, Lapi F, Volpi R, Menniti-Ippolito F, Gori L, Mugelli A, Firenzuoli F, Vannacci A.
PMID: 21274401
Evid Based Complement Alternat Med. 2011;2011:612150. doi: 10.1155/2011/612150. Epub 2011 Jan 09.

Introduction. The safety of vitamin K antagonists (VKA) use can be compromised by many popular herbal supplements taken by individuals. The literature reports that 30% of warfarin-treated patients self-medicates with herbs. Possible interactions represent an health risk. We aimed...

Thromboprophylaxis in total hip-replacement surgery in Europe: acenocoumarol, fondaparinux, dabigatran and rivaroxban.

Expert review of pharmacoeconomics & outcomes research

Ivanovic N, Beinema M, Brouwers JR, Naunton M, Postma MJ.
PMID: 20528430
Expert Rev Pharmacoecon Outcomes Res. 2007 Feb;7(1):49-58. doi: 10.1586/14737167.7.1.49.

This paper reviews the clinical and pharmacoeconomic studies that have been conducted within Europe for patients undergoing elective hip-replacement surgery. Additionally, we offer a perspective on the possible future clinical use of new agents in orthopedic surgery, such as...

Pharmacogenetics of anticoagulants.

Human genomics and proteomics : HGP

Rane A, Lindh JD.
PMID: 20981234
Hum Genomics Proteomics. 2010 Sep 13;2010:754919. doi: 10.4061/2010/754919.

Warfarin, acenocoumarol, and phenprocoumon are among the major anticoagulant drugs worldwide. Because of their low therapeutic index and serious adverse reactions (ADRs), their wide use, and their varying kinetics and pharmacogenetic dependence, it is of great importance to explore...

Alternative to oral dicoumarin anticoagulants: Considerations in dental care.

Journal of clinical and experimental dentistry

Mingarro-de-León A, Chaveli-López B.
PMID: 24455094
J Clin Exp Dent. 2013 Dec 01;5(5):e273-8. doi: 10.4317/jced.51226. eCollection 2013 Dec 01.

INTRODUCTION: For over 50 years, vitamin K antagonists such as warfarin (Aldocumar®) and acenocoumarol (Sintrom®) have been the gold standard for reducing the risk of cerebrovascular events. In the last 5 years alternative anticoagulants have been evaluated that act...

Relationship between drug interactions and drug-related negative clinical outcomes.

Pharmacy practice

Cremades J, Gonzalo M, Arrebola I.
PMID: 25147590
Pharm Pract (Granada). 2009 Jan;7(1):34-9. doi: 10.4321/s1886-36552009000100005. Epub 2009 Mar 15.

UNLABELLED: Drug interactions may represent an iatrogenic risk that should be controlled in community pharmacies at the dispensing level.AIM: We analyzed the association between potential drug-drug interactions (DDIs) and negative clinical outcomes.METHODS: WE USED DISPENSING DATA FROM TWO COMMUNITY...

The new oral anticoagulants.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

Verheugt FW.
PMID: 20657677
Neth Heart J. 2010 Jun;18(6):314-8. doi: 10.1007/BF03091782.

In patients with nonvalvular atrial fibrillation oral anticoagulation with the vitamin K antagonists acenocoumarol, phenprocoumon and warfarin reduces the risk of stroke by more than 60%, whereas single or double antiplatelet therapy is much less effective and sometimes associated...

Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies.

Thrombosis journal

Prins MH, Lensing AW, Bauersachs R, van Bellen B, Bounameaux H, Brighton TA, Cohen AT, Davidson BL, Decousus H, Raskob GE, Berkowitz SD, Wells PS.
PMID: 24053656
Thromb J. 2013 Sep 20;11(1):21. doi: 10.1186/1477-9560-11-21.

BACKGROUND: Standard treatment for venous thromboembolism (VTE) consists of a heparin combined with vitamin K antagonists. Direct oral anticoagulants have been investigated for acute and extended treatment of symptomatic VTE; their use could avoid parenteral treatment and/or laboratory monitoring...

The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations.

Personalized medicine

Kirchheiner J, Tsahuridu M, Jabrane W, Roots I, Brockmöller J.
PMID: 29793229
Per Med. 2004 Dec;1(1):63-84. doi: 10.1517/17410541.1.1.63.

CYP2C9 is the major human enzyme of the cytochrome P450 2C subfamily and metabolizes approximately 10% of all therapeutically relevant drugs. Two inherited SNPs termed CYP2C9*2 (Arg144Cys) and *3 (Ile359Leu) are known to affect catalytic function. Numerous rare or...

Showing 1 to 12 of 84 entries