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Showing 1 to 12 of 70 entries
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Inframammary Dermatitis: A Case of Localized Late-Onset Darier's Disease.

Case reports in dermatology

Linder D, Marinello E, Donisi PM, Salmaso R, Zattra E, Zampetti A.
PMID: 27504089
Case Rep Dermatol. 2016 Jul 12;8(2):189-92. doi: 10.1159/000447482. eCollection 2016.

Darier's disease (DD) is an autosomal dominant inherited genodermatosis which is often under- or misdiagnosed. In the majority of cases, the disease manifests in adolescents or young adults with small brownish-yellow, warty, hyperkeratotic papules in multiple seborrheic areas of...

Hydrogel containing adapalene- and dapsone-loaded lipid-core nanocapsules for cutaneous application: development, characterization, in vitro irritation and permeation studies.

Drug development and industrial pharmacy

Pereira RL, Leites FI, Paese K, Sponchiado RM, Michalowski CB, Guterres SS, Schapoval EE.
PMID: 27161601
Drug Dev Ind Pharm. 2016 Dec;42(12):2001-2008. doi: 10.1080/03639045.2016.1188110. Epub 2016 May 31.

Lipid-core polymeric nanocapsule suspensions containing adapalene and dapsone (AD-LCNC) were developed and incorporated in a Carbopol 940Ā® hydrogel (AD-LCNC HG). A nanoemulsion (AD-NE), similarly prepared but omitting the polymer, was developed and also incorporated in a Carbopol 940

Validated Stability-Indicating RP-HPLC Method for the Estimation of Degradation Behaviour of Organic Peroxide and Third-Generation Synthetic Retinoids in Topical Pharmaceutical Dosage Formulation.

Scientia pharmaceutica

Roy C, Panigrahi L, Chakrabarty J.
PMID: 26839821
Sci Pharm. 2015 Feb 11;83(2):321-38. doi: 10.3797/scipharm.1412-10. Print 2015.

The objective of the current study was to establish a validated stability-indicating, high-performance liquid chromatographic method to determine the purity of benzoyl peroxide (BPO) and adapalene (ADP) in the presence of its impurities, forced degradation products, and placebo in...

Treatment of cervical intraepithelial neoplasia levels 2 and 3 with adapalene, a retinoid-related molecule.

Journal of lower genital tract disease

DiSilvestro PA, DiSilvestro JM, Lernhardt W, Pfahl M, Mannel RS.
PMID: 17043560
J Low Genit Tract Dis. 2001 Jan;5(1):33-7. doi: 10.1046/j.1526-0976.2001.51007.x.

OBJECTIVES: This study examined dose scheduling, safety, and efficacy of adapalene in the treatment of CIN2 and CIN3.METHODS: Patients were instructed on insertion and removal of an adapalene delivery system. Treatment regimens of 4, 8, and 14 days were...

Safety and efficacy of adapalene gel 0.1% in acne vulgaris: results of a post-marketing surveillance study.

Indian journal of dermatology, venereology and leprology

Percy SH.
PMID: 17642911
Indian J Dermatol Venereol Leprol. 2003 Jul-Aug;69(4):277-80.

INTRODUCTION: Adapalene is a novel retinoid indicated for the topical treatment of acne vulgaris. The drug was introduced in India in 2001.AIMS: A post-marketing surveillance study was conducted to assess the safety and efficacy of adapalene gel 0.1% when...

The immune reconstitution inflammatory syndrome.

Indian journal of dermatology

Bosamiya SS.
PMID: 22121257
Indian J Dermatol. 2011 Sep-Oct;56(5):476-9. doi: 10.4103/0019-5154.87114.

A paradoxical clinical worsening of a known condition or the appearance of a new condition after initiating antiretroviral therapy in HIV-infected patients is defined as immune reconstitution inflammatory syndrome (IRIS). Because of wide variation in clinical presentation and the...

Plantar warts treated with topical adapalene.

Indian journal of dermatology

Gupta R.
PMID: 22121266
Indian J Dermatol. 2011 Sep-Oct;56(5):513-4. doi: 10.4103/0019-5154.87135.

BACKGROUND: Treatment of plantar warts caused by human papilloma virus (HPV) strain types 1, 2 and 4 is often difficult and a challenging problem. Various therapeutic modalities available for treating this problem have not been uniformly successful.PURPOSE: The purpose...

In vitro percutaneous absorption of benzoyl peroxide from three fixed combination acne formulations.

The Journal of clinical and aesthetic dermatology

Zeichner JA, Bhatt V, Pillai R.
PMID: 24003346
J Clin Aesthet Dermatol. 2013 Aug;6(8):19-22.

Fixed combination therapy in acne is standard of care, and benzoyl peroxide is a common component of a number of fixed-dose combination products available today. Given that benzoyl peroxide can cause concentration-dependent irritation, newer combinations have been developed utilizing...

Adapalene 0.3% Gel Shows Efficacy for the Treatment of Atrophic Acne Scars.

Dermatology and therapy

Loss MJ, Leung S, Chien A, Kerrouche N, Fischer AH, Kang S.
PMID: 29549598
Dermatol Ther (Heidelb). 2018 Jun;8(2):245-257. doi: 10.1007/s13555-018-0231-8. Epub 2018 Mar 16.

INTRODUCTION: Scarring is an unfortunate clinical outcome of acne. Current treatment options for atrophic acne scars are dominated by non-pharmacological, invasive procedures which may not be suitable or affordable to all patients. This phase II, single-center, open-label, exploratory study...

Adapalene 0.3% for the treatment of acne in women.

The Journal of clinical and aesthetic dermatology

Berson D, Alexis A.
PMID: 24155991
J Clin Aesthet Dermatol. 2013 Oct;6(10):32-5.

SETTING: Acne vulgaris is characterized by comedones, papules, pustules, and secondary lesions. Historically, it has been considered a disease primarily affecting adolescents, but recent reports over the past three decades suggest an increasing prevalence in adults, particularly women. Adapalene...

Targeted Topical Delivery of Retinoids in the Management of Acne Vulgaris: Current Formulations and Novel Delivery Systems.

Pharmaceutics

Latter G, Grice JE, Mohammed Y, Roberts MS, Benson HAE.
PMID: 31554188
Pharmaceutics. 2019 Sep 24;11(10). doi: 10.3390/pharmaceutics11100490.

Acne vulgaris is a common inflammatory pilosebaceous condition that affects 80-90% of adolescents. Since the introduction of tretinoin over 40 years ago, topical retinoid products have been a mainstay of acne treatment. The retinoids are very effective in addressing...

Highlights of Skin Disease Education Foundations 42nd Annual Hawaii Dermatology Seminar.

Seminars in cutaneous medicine and surgery

Baldwin HE, Stein Gold LF, Gordon KB, Green JB, Leonardi CL, Sengelmann RD.
PMID: 30016379
Semin Cutan Med Surg. 2018 Jun;37(4):S75-S84. doi: 10.12788/j.sder.2018.031.

Updates on managing some of the most common dermatologic conditions for which patients seek care illuminated presentations at the Skin Disease Education Foundation's 42nd Annual Hawaii Dermatology SeminarĀ®. This educational supplement summarizes the highlights of clinical sessions presented during...

Showing 1 to 12 of 70 entries