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Aggrecan: Approaches to Study Biophysical and Biomechanical Properties.

Methods in molecular biology (Clifton, N.J.)

Nia HT, Ortiz C, Grodzinsky A.
PMID: 34626381
Methods Mol Biol. 2022;2303:209-226. doi: 10.1007/978-1-0716-1398-6_17.

Aggrecan, the most abundant extracellular proteoglycan in cartilage (~35% by dry weight), plays a key role in the biophysical and biomechanical properties of cartilage. Here, we review several approaches based on atomic force microscopy (AFM) to probe the physical,...

Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes.

Oncotarget

Bao J, Ma C, Ran J, Xiong Y, Yan S, Wu L.
PMID: 29299122
Oncotarget. 2017 Aug 24;8(66):109962-109972. doi: 10.18632/oncotarget.20584. eCollection 2017 Dec 15.

To investigate the inflammatory effect of Interleukin 18 (IL-18) on rat chondrocytes and the involvement of Wnt/β-catenin and Hedgehog pathways, the mRNA and protein level of matix-degrading enzymes (MMP-2, 3, 9,13 and aggrecanses) and chondrocyte-specific proteins (Collagen II and...

Retrospective Diagnosis of a Novel .

Frontiers in genetics

Mancioppi V, Prodam F, Mellone S, Ricotti R, Giglione E, Grasso N, Vurchio D, Petri A, Rabbone I, Giordano M, Bellone S.
PMID: 34456977
Front Genet. 2021 Aug 12;12:708864. doi: 10.3389/fgene.2021.708864. eCollection 2021.

Short stature is a frequent disorder in the pediatric population and can be caused by multiple factors. In the last few years, the introduction of Next Generation Sequencing (NGS) in the molecular diagnostic workflow led to the discovery of...

The morphology and selected biological properties of articular cartilage.

Ortopedia, traumatologia, rehabilitacja

Hyc A, Osiecka-Iwan A, Jóźwiak J, Moskalewski S.
PMID: 17986977
Ortop Traumatol Rehabil. 2001 Apr 30;3(2):151-62.

The purpose of this article is to present the current state of knowledge regarding the structure and functions of articular cartilage. Articular cartilage is constructed with hyaline cartilage tissue. It is composed of chondrocytes located in lacunae and the...

Showing 1 to 4 of 4 entries