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Cancer protection of soy resembles cancer protection during pregnancy.

Hormone molecular biology and clinical investigation

Rohr UD, Gocan AG, Bachg D, Schindler AE.
PMID: 25961211
Horm Mol Biol Clin Investig. 2010 Dec 01;3(2):391-409. doi: 10.1515/HMBCI.2010.063.

It has been established that carrying a pregnancy to full-term at an early age can protect against contracting cancer by up to 50% in later life. The trophoblast theory of cancer states that trophoblast and cancer tissue are very...

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Rohr UD, Gocan AG, Bachg D, et al. Cancer protection of soy resembles cancer protection during pregnancy. Horm Mol Biol Clin Investig. 2010;3(2):391-409doi: 10.1515/HMBCI.2010.063.
Rohr, U. D., Gocan, A. G., Bachg, D., & Schindler, A. E. (2010). Cancer protection of soy resembles cancer protection during pregnancy. Hormone molecular biology and clinical investigation, 3(2), 391-409. https://doi.org/10.1515/HMBCI.2010.063
Rohr, Uwe D, et al. "Cancer protection of soy resembles cancer protection during pregnancy." Hormone molecular biology and clinical investigation vol. 3,2 (2010): 391-409. doi: https://doi.org/10.1515/HMBCI.2010.063
Rohr UD, Gocan AG, Bachg D, Schindler AE. Cancer protection of soy resembles cancer protection during pregnancy. Horm Mol Biol Clin Investig. 2010 Dec 01;3(2):391-409. doi: 10.1515/HMBCI.2010.063. PMID: 25961211.
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Metabolic syndrome, levels of androgens, and changes of erectile dysfunction and quality of life impairment 1 year after radical prostatectomy.

Asian journal of andrology

Neuzillet Y, Rouanne M, Dreyfus JF, Raynaud JP, Schneider M, Roupret M, Drouin S, Galiano M, Cathelinau X, Lebret T, Botto H.
PMID: 33565427
Asian J Androl. 2021 Jul-Aug;23(4):370-375. doi: 10.4103/aja.aja_88_20.

Robust data evaluating the association of preoperative parameters of the patients with quality of life after radical prostatectomy are lacking. We investigated whether clinical and biological preoperative characteristics of the patients were associated with impaired patient-reported quality of life...

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Neuzillet Y, Rouanne M, Dreyfus JF, et al. Metabolic syndrome, levels of androgens, and changes of erectile dysfunction and quality of life impairment 1 year after radical prostatectomy. Asian J Androl. 2021;23(4):370-375doi: 10.4103/aja.aja_88_20.
Neuzillet, Y., Rouanne, M., Dreyfus, J. F., Raynaud, J. P., Schneider, M., Roupret, M., Drouin, S., Galiano, M., Cathelinau, X., Lebret, T., & Botto, H. (2021). Metabolic syndrome, levels of androgens, and changes of erectile dysfunction and quality of life impairment 1 year after radical prostatectomy. Asian journal of andrology, 23(4), 370-375. https://doi.org/10.4103/aja.aja_88_20
Neuzillet, Yann, et al. "Metabolic syndrome, levels of androgens, and changes of erectile dysfunction and quality of life impairment 1 year after radical prostatectomy." Asian journal of andrology vol. 23,4 (2021): 370-375. doi: https://doi.org/10.4103/aja.aja_88_20
Neuzillet Y, Rouanne M, Dreyfus JF, Raynaud JP, Schneider M, Roupret M, Drouin S, Galiano M, Cathelinau X, Lebret T, Botto H. Metabolic syndrome, levels of androgens, and changes of erectile dysfunction and quality of life impairment 1 year after radical prostatectomy. Asian J Androl. 2021 Jul-Aug;23(4):370-375. doi: 10.4103/aja.aja_88_20. PMID: 33565427; PMCID: PMC8269836.
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Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study.

PloS one

Tanabe H, Mutai H, Sasayama D, Sasamoto H, Miyashiro Y, Sugiyama N, Washizuka S.
PMID: 34910781
PLoS One. 2021 Dec 15;16(12):e0261440. doi: 10.1371/journal.pone.0261440. eCollection 2021.

Animal experiments have consistently shown that estrogen receptor β (ERβ)-selective ligands have antidepressant and anxiolytic effects. In humans, endogenous ligands for ERβ include 5α-androstane-3β, 17β-diol (3βAdiol) and androstenediol (Δ5-diol). We determined, for the first time, the exact serum levels...

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Tanabe H, Mutai H, Sasayama D, et al. Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study. PLoS One. 2021;16(12):e0261440doi: 10.1371/journal.pone.0261440.
Tanabe, H., Mutai, H., Sasayama, D., Sasamoto, H., Miyashiro, Y., Sugiyama, N., & Washizuka, S. (2021). Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study. PloS one, 16(12), e0261440. https://doi.org/10.1371/journal.pone.0261440
Tanabe, Haruka, et al. "Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study." PloS one vol. 16,12 (2021): e0261440. doi: https://doi.org/10.1371/journal.pone.0261440
Tanabe H, Mutai H, Sasayama D, Sasamoto H, Miyashiro Y, Sugiyama N, Washizuka S. Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study. PLoS One. 2021 Dec 15;16(12):e0261440. doi: 10.1371/journal.pone.0261440. eCollection 2021. PMID: 34910781.
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The effects of Delta-androstenedione and Delta-androstenediol on castrated and ovariectomized rats.

The Biochemical journal

Korenchevsky V, Dennison M, Eldridge M.
PMID: 16746359
Biochem J. 1937 Mar;31(3):467-74. doi: 10.1042/bj0310467.

No abstract available.

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Korenchevsky V, Dennison M, Eldridge M. The effects of Delta-androstenedione and Delta-androstenediol on castrated and ovariectomized rats. Biochem J. 1937;31(3):467-74doi: 10.1042/bj0310467.
Korenchevsky, V., Dennison, M., & Eldridge, M. (1937). The effects of Delta-androstenedione and Delta-androstenediol on castrated and ovariectomized rats. The Biochemical journal, 31(3), 467-74. https://doi.org/10.1042/bj0310467
Korenchevsky, V, et al. "The effects of Delta-androstenedione and Delta-androstenediol on castrated and ovariectomized rats." The Biochemical journal vol. 31,3 (1937): 467-74. doi: https://doi.org/10.1042/bj0310467
Korenchevsky V, Dennison M, Eldridge M. The effects of Delta-androstenedione and Delta-androstenediol on castrated and ovariectomized rats. Biochem J. 1937 Mar;31(3):467-74. doi: 10.1042/bj0310467. PMID: 16746359; PMCID: PMC1266957.
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The co-operative activity of testosterone propionate with Delta-androstenediol and with oestradiol in male rats.

The Biochemical journal

Korenchevsky V, Dennison M.
PMID: 16746409
Biochem J. 1937 Jun;31(6):862-4. doi: 10.1042/bj0310862.

No abstract available.

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Korenchevsky V, Dennison M. The co-operative activity of testosterone propionate with Delta-androstenediol and with oestradiol in male rats. Biochem J. 1937;31(6):862-4doi: 10.1042/bj0310862.
Korenchevsky, V., & Dennison, M. (1937). The co-operative activity of testosterone propionate with Delta-androstenediol and with oestradiol in male rats. The Biochemical journal, 31(6), 862-4. https://doi.org/10.1042/bj0310862
Korenchevsky, V, and Dennison, M. "The co-operative activity of testosterone propionate with Delta-androstenediol and with oestradiol in male rats." The Biochemical journal vol. 31,6 (1937): 862-4. doi: https://doi.org/10.1042/bj0310862
Korenchevsky V, Dennison M. The co-operative activity of testosterone propionate with Delta-androstenediol and with oestradiol in male rats. Biochem J. 1937 Jun;31(6):862-4. doi: 10.1042/bj0310862. PMID: 16746409; PMCID: PMC1267019.
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Balancing steroidal hormone cascade in treatment-resistant veteran soldiers with PTSD using a fermented soy product (FSWW08): a pilot study.

Hormone molecular biology and clinical investigation

Gocan AG, Bachg D, Schindler AE, Rohr UD.
PMID: 25436688
Horm Mol Biol Clin Investig. 2012 Jun;10(3):301-14. doi: 10.1515/hmbci-2011-0135.

UNLABELLED: Abstract Introduction: A clinical study was conducted to determine steroidal hormone cascade in the blood to relate them to mental performance with the Clinician-Administered PTSD scale (CAPS), serum lipid concentrations, and steroidal hormones, particularly cortisol, testosterone, estradiol, dehydroepiandrosterone...

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Gocan AG, Bachg D, Schindler AE, et al. Balancing steroidal hormone cascade in treatment-resistant veteran soldiers with PTSD using a fermented soy product (FSWW08): a pilot study. Horm Mol Biol Clin Investig. 2012;10(3):301-14doi: 10.1515/hmbci-2011-0135.
Gocan, A. G., Bachg, D., Schindler, A. E., & Rohr, U. D. (2012). Balancing steroidal hormone cascade in treatment-resistant veteran soldiers with PTSD using a fermented soy product (FSWW08): a pilot study. Hormone molecular biology and clinical investigation, 10(3), 301-14. https://doi.org/10.1515/hmbci-2011-0135
Gocan, Anca G, et al. "Balancing steroidal hormone cascade in treatment-resistant veteran soldiers with PTSD using a fermented soy product (FSWW08): a pilot study." Hormone molecular biology and clinical investigation vol. 10,3 (2012): 301-14. doi: https://doi.org/10.1515/hmbci-2011-0135
Gocan AG, Bachg D, Schindler AE, Rohr UD. Balancing steroidal hormone cascade in treatment-resistant veteran soldiers with PTSD using a fermented soy product (FSWW08): a pilot study. Horm Mol Biol Clin Investig. 2012 Jun;10(3):301-14. doi: 10.1515/hmbci-2011-0135. PMID: 25436688.
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Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study.

PloS one

Tanabe H, Mutai H, Sasayama D, Sasamoto H, Miyashiro Y, Sugiyama N, Washizuka S.
PMID: 34910781
PLoS One. 2021 Dec 15;16(12):e0261440. doi: 10.1371/journal.pone.0261440. eCollection 2021.

Animal experiments have consistently shown that estrogen receptor β (ERβ)-selective ligands have antidepressant and anxiolytic effects. In humans, endogenous ligands for ERβ include 5α-androstane-3β, 17β-diol (3βAdiol) and androstenediol (Δ5-diol). We determined, for the first time, the exact serum levels...

Cite
Tanabe H, Mutai H, Sasayama D, et al. Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study. PLoS One. 2021;16(12):e0261440doi: 10.1371/journal.pone.0261440.
Tanabe, H., Mutai, H., Sasayama, D., Sasamoto, H., Miyashiro, Y., Sugiyama, N., & Washizuka, S. (2021). Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study. PloS one, 16(12), e0261440. https://doi.org/10.1371/journal.pone.0261440
Tanabe, Haruka, et al. "Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study." PloS one vol. 16,12 (2021): e0261440. doi: https://doi.org/10.1371/journal.pone.0261440
Tanabe H, Mutai H, Sasayama D, Sasamoto H, Miyashiro Y, Sugiyama N, Washizuka S. Sex differences in serum levels of 5α-androstane-3β, 17β-diol, and androstenediol in the young adults: A liquid chromatography-tandem mass spectrometry study. PLoS One. 2021 Dec 15;16(12):e0261440. doi: 10.1371/journal.pone.0261440. eCollection 2021. PMID: 34910781; PMCID: PMC8673626.
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Simultaneous measurement of 18 steroids in human and mouse serum by liquid chromatography-mass spectrometry without derivatization to profile the classical and alternate pathways of androgen synthesis and metabolism.

Clinical mass spectrometry (Del Mar, Calif.)

Desai R, Harwood DT, Handelsman DJ.
PMID: 34841072
Clin Mass Spectrom. 2019 Jan 06;11:42-51. doi: 10.1016/j.clinms.2018.12.003. eCollection 2019 Jan.

BACKGROUND: The recently identified alternate, or backdoor, pathway of DHT synthesis provides important novel information on androgen biosynthesis beyond the classical pathway. We report a rapid and versatile liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to simultaneously and accurately quantify...

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Desai R, Harwood DT, Handelsman DJ. Simultaneous measurement of 18 steroids in human and mouse serum by liquid chromatography-mass spectrometry without derivatization to profile the classical and alternate pathways of androgen synthesis and metabolism. Clin Mass Spectrom. 2019;11:42-51doi: 10.1016/j.clinms.2018.12.003.
Desai, R., Harwood, D. T., & Handelsman, D. J. (2019). Simultaneous measurement of 18 steroids in human and mouse serum by liquid chromatography-mass spectrometry without derivatization to profile the classical and alternate pathways of androgen synthesis and metabolism. Clinical mass spectrometry (Del Mar, Calif.), 1142-51. https://doi.org/10.1016/j.clinms.2018.12.003
Desai, Reena, et al. "Simultaneous measurement of 18 steroids in human and mouse serum by liquid chromatography-mass spectrometry without derivatization to profile the classical and alternate pathways of androgen synthesis and metabolism." Clinical mass spectrometry (Del Mar, Calif.) vol. 11 (2019): 42-51. doi: https://doi.org/10.1016/j.clinms.2018.12.003
Desai R, Harwood DT, Handelsman DJ. Simultaneous measurement of 18 steroids in human and mouse serum by liquid chromatography-mass spectrometry without derivatization to profile the classical and alternate pathways of androgen synthesis and metabolism. Clin Mass Spectrom. 2019 Jan 06;11:42-51. doi: 10.1016/j.clinms.2018.12.003. eCollection 2019 Jan. PMID: 34841072; PMCID: PMC8620903.
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Metabolomics study reveals systematic metabolic dysregulation and early detection markers associated with incident pancreatic cancer.

International journal of cancer

Wang S, Li M, Yan L, He M, Lin H, Xu Y, Wan Q, Qin G, Chen G, Xu M, Wang G, Qin Y, Luo Z, Tang X, Wang T, Zhao Z, Xu Y, Chen Y, Huo Y, Hu R, Ye Z, Dai M, Shi L, Gao Z, Su Q, Mu Y, Zhao J, Chen L, Zeng T, Yu X, Li Q, Shen F, Chen L, Zhang Y, Wang Y, Deng H, Liu C, Wu S, Yang T, Li D, Ning G, Wu T, Wang W, Bi Y, Lu J.
PMID: 34792202
Int J Cancer. 2021 Nov 18; doi: 10.1002/ijc.33877. Epub 2021 Nov 18.

Biomarkers for early detection of pancreatic cancer are in urgent need. To explore systematic circulating metabolites unbalance and identify potential biomarkers for pancreatic cancer in prospective Chinese cohorts, we conducted an untargeted metabolomics study in subjects with incident pancreatic...

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Wang S, Li M, Yan L, et al. Metabolomics study reveals systematic metabolic dysregulation and early detection markers associated with incident pancreatic cancer. Int J Cancer. 2021;doi: 10.1002/ijc.33877.
Wang, S., Li, M., Yan, L., He, M., Lin, H., Xu, Y., Wan, Q., Qin, G., Chen, G., Xu, M., Wang, G., Qin, Y., Luo, Z., Tang, X., Wang, T., Zhao, Z., Xu, Y., Chen, Y., Huo, Y., Hu, R., Ye, Z., Dai, M., Shi, L., Gao, Z., Su, Q., Mu, Y., Zhao, J., Chen, L., Zeng, T., Yu, X., Li, Q., Shen, F., Chen, L., Zhang, Y., Wang, Y., Deng, H., Liu, C., Wu, S., Yang, T., Li, D., Ning, G., Wu, T., Wang, W., Bi, Y., Lu, J. (2021). Metabolomics study reveals systematic metabolic dysregulation and early detection markers associated with incident pancreatic cancer. International journal of cancer, . https://doi.org/10.1002/ijc.33877
Wang, Shuangyuan, et al. "Metabolomics study reveals systematic metabolic dysregulation and early detection markers associated with incident pancreatic cancer." International journal of cancer vol. (2021). doi: https://doi.org/10.1002/ijc.33877
Wang S, Li M, Yan L, He M, Lin H, Xu Y, Wan Q, Qin G, Chen G, Xu M, Wang G, Qin Y, Luo Z, Tang X, Wang T, Zhao Z, Xu Y, Chen Y, Huo Y, Hu R, Ye Z, Dai M, Shi L, Gao Z, Su Q, Mu Y, Zhao J, Chen L, Zeng T, Yu X, Li Q, Shen F, Chen L, Zhang Y, Wang Y, Deng H, Liu C, Wu S, Yang T, Li D, Ning G, Wu T, Wang W, Bi Y, Lu J. Metabolomics study reveals systematic metabolic dysregulation and early detection markers associated with incident pancreatic cancer. Int J Cancer. 2021 Nov 18; doi: 10.1002/ijc.33877. Epub 2021 Nov 18. PMID: 34792202.
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Relationship of preoperative androgen levels and metabolic syndrome with quality of life and erectile function in patients who are to undergo radical prostatectomy.

Asian journal of andrology

Neuzillet Y, Dreyfus JF, Raynaud JP, Rouanne M, Schneider M, Roupret M, Drouin S, Galiano M, Cathelineau X, Lebret T, Botto H.
PMID: 33762475
Asian J Androl. 2021 Sep-Oct;23(5):520-526. doi: 10.4103/aja.aja_3_21.

This study aims to investigate whether clinical and biological preoperative characteristics of patients who were to undergo radical prostatectomy were associated with impairment in patient-reported quality of life (QoL) and erectile dysfunction immediately before intervention. We evaluated patient-reported outcomes...

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Neuzillet Y, Dreyfus JF, Raynaud JP, et al. Relationship of preoperative androgen levels and metabolic syndrome with quality of life and erectile function in patients who are to undergo radical prostatectomy. Asian J Androl. 2021;23(5):520-526doi: 10.4103/aja.aja_3_21.
Neuzillet, Y., Dreyfus, J. F., Raynaud, J. P., Rouanne, M., Schneider, M., Roupret, M., Drouin, S., Galiano, M., Cathelineau, X., Lebret, T., & Botto, H. (2021). Relationship of preoperative androgen levels and metabolic syndrome with quality of life and erectile function in patients who are to undergo radical prostatectomy. Asian journal of andrology, 23(5), 520-526. https://doi.org/10.4103/aja.aja_3_21
Neuzillet, Yann, et al. "Relationship of preoperative androgen levels and metabolic syndrome with quality of life and erectile function in patients who are to undergo radical prostatectomy." Asian journal of andrology vol. 23,5 (2021): 520-526. doi: https://doi.org/10.4103/aja.aja_3_21
Neuzillet Y, Dreyfus JF, Raynaud JP, Rouanne M, Schneider M, Roupret M, Drouin S, Galiano M, Cathelineau X, Lebret T, Botto H. Relationship of preoperative androgen levels and metabolic syndrome with quality of life and erectile function in patients who are to undergo radical prostatectomy. Asian J Androl. 2021 Sep-Oct;23(5):520-526. doi: 10.4103/aja.aja_3_21. PMID: 33762475; PMCID: PMC8451490.
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The Safety and Efficacy of Anabolic Steroid Precursors: What is the Scientific Evidence?.

Journal of athletic training

Powers ME.
PMID: 16558675
J Athl Train. 2002 Jul;37(3):300-5.

OBJECTIVE: Anabolic steroid precursors have gained widespread popularity as ergogenic supplements. Advertisements for these supplements claim that they increase endogenous testosterone production and protein synthesis, resulting in increased lean body mass and strength during training. At this time scientific...

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Powers ME. The Safety and Efficacy of Anabolic Steroid Precursors: What is the Scientific Evidence?. J Athl Train. 2002;37(3):300-5
Powers, M. E. (2002). The Safety and Efficacy of Anabolic Steroid Precursors: What is the Scientific Evidence?. Journal of athletic training, 37(3), 300-5.
Powers, Michael E. "The Safety and Efficacy of Anabolic Steroid Precursors: What is the Scientific Evidence?." Journal of athletic training vol. 37,3 (2002): 300-5.
Powers ME. The Safety and Efficacy of Anabolic Steroid Precursors: What is the Scientific Evidence?. J Athl Train. 2002 Jul;37(3):300-5. PMID: 16558675; PMCID: PMC164360.
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5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice.

Autoimmune diseases

Nicoletti F, Auci DL, Mangano K, Flores-Riveros J, Villegas S, Frincke JM, Reading CL, Offner H.
PMID: 21188238
Autoimmune Dis. 2010 May 18;2010:757432. doi: 10.4061/2010/757432.

Androstenediol (androst-5-ene-3β,17β-diol; 5-AED), a natural adrenal steroid, has been shown to suppress experimental autoimmune encephalomyelitis (EAE) in female SJL/J mice. We here report that 5-AED limits inflammation and proinflammatory cytokines including TNFα in murine models of carrageenan-induced pleurisy and...

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Nicoletti F, Auci DL, Mangano K, et al. 5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice. Autoimmune Dis. 2010;2010:757432doi: 10.4061/2010/757432.
Nicoletti, F., Auci, D. L., Mangano, K., Flores-Riveros, J., Villegas, S., Frincke, J. M., Reading, C. L., & Offner, H. (2010). 5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice. Autoimmune diseases, 2010757432. https://doi.org/10.4061/2010/757432
Nicoletti, Ferdinando, et al. "5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice." Autoimmune diseases vol. 2010 (2010): 757432. doi: https://doi.org/10.4061/2010/757432
Nicoletti F, Auci DL, Mangano K, Flores-Riveros J, Villegas S, Frincke JM, Reading CL, Offner H. 5-androstenediol ameliorates pleurisy, septic shock, and experimental autoimmune encephalomyelitis in mice. Autoimmune Dis. 2010 May 18;2010:757432. doi: 10.4061/2010/757432. PMID: 21188238; PMCID: PMC3005896.
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Showing 1 to 12 of 21 entries