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Analysis of the function of microRNA-375 in humans using bioinformatics.

Biomedical reports

Chen X, Li B, Luo R, Cai S, Zhang C, Cao X.
PMID: 28515914
Biomed Rep. 2017 May;6(5):561-566. doi: 10.3892/br.2017.889. Epub 2017 Apr 10.

MicroRNA-375 (miR-375) is expressed at low levels in many types of solid tumor, particularly in gastrointestinal tumors. It is considered to be important in the development of cancer and certain diseases. Thus, more detailed knowledge is required on the...

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Chen X, Li B, Luo R, et al. Analysis of the function of microRNA-375 in humans using bioinformatics. Biomed Rep. 2017;6(5):561-566doi: 10.3892/br.2017.889.
Chen, X., Li, B., Luo, R., Cai, S., Zhang, C., & Cao, X. (2017). Analysis of the function of microRNA-375 in humans using bioinformatics. Biomedical reports, 6(5), 561-566. https://doi.org/10.3892/br.2017.889
Chen, Xiaohua, et al. "Analysis of the function of microRNA-375 in humans using bioinformatics." Biomedical reports vol. 6,5 (2017): 561-566. doi: https://doi.org/10.3892/br.2017.889
Chen X, Li B, Luo R, Cai S, Zhang C, Cao X. Analysis of the function of microRNA-375 in humans using bioinformatics. Biomed Rep. 2017 May;6(5):561-566. doi: 10.3892/br.2017.889. Epub 2017 Apr 10. PMID: 28515914; PMCID: PMC5431329.
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Effective prediction of preeclampsia by measuring serum angiotensin II, urinary angiotensinogen and urinary transforming growth factor β1.

Experimental and therapeutic medicine

Zhang L, Zhou Y, Wu Q, Fan W, Ye J, Chen Y, Wu Y, Niu J, Gu Y.
PMID: 28672944
Exp Ther Med. 2017 Jul;14(1):391-397. doi: 10.3892/etm.2017.4484. Epub 2017 May 22.

The aim of the current study was to analyze serum angiotensin II (Ang II), urinary angiotensinogen (AGT) and urinary transforming growth factor β1 (TGFβ1) levels in relation to the clinical manifestation of preeclampsia, and to explore the effects of...

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Zhang L, Zhou Y, Wu Q, et al. Effective prediction of preeclampsia by measuring serum angiotensin II, urinary angiotensinogen and urinary transforming growth factor β1. Exp Ther Med. 2017;14(1):391-397doi: 10.3892/etm.2017.4484.
Zhang, L., Zhou, Y., Wu, Q., Fan, W., Ye, J., Chen, Y., Wu, Y., Niu, J., & Gu, Y. (2017). Effective prediction of preeclampsia by measuring serum angiotensin II, urinary angiotensinogen and urinary transforming growth factor β1. Experimental and therapeutic medicine, 14(1), 391-397. https://doi.org/10.3892/etm.2017.4484
Zhang, Lihong, et al. "Effective prediction of preeclampsia by measuring serum angiotensin II, urinary angiotensinogen and urinary transforming growth factor β1." Experimental and therapeutic medicine vol. 14,1 (2017): 391-397. doi: https://doi.org/10.3892/etm.2017.4484
Zhang L, Zhou Y, Wu Q, Fan W, Ye J, Chen Y, Wu Y, Niu J, Gu Y. Effective prediction of preeclampsia by measuring serum angiotensin II, urinary angiotensinogen and urinary transforming growth factor β1. Exp Ther Med. 2017 Jul;14(1):391-397. doi: 10.3892/etm.2017.4484. Epub 2017 May 22. PMID: 28672944; PMCID: PMC5488619.
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Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats.

Cardiovascular endocrinology

Groban L, Wang H, Machado FS, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI.
PMID: 23795309
Cardiovasc Endocrinol. 2012 Sep 01;1(3):49-58. doi: 10.1097/XCE.0b013e32835a2159.

OBJECTIVES: Long-term systemic blockade of the renin-angiotensin system (RAS) with either an angiotensin (Ang) II type 1 receptor antagonist or an angiotensin-converting enzyme inhibitor attenuates age-related cardiac remodeling and oxidative damage, and improves myocardial relaxation. However, the role of...

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Groban L, Wang H, Machado FS, et al. Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovasc Endocrinol. 2012;1(3):49-58doi: 10.1097/XCE.0b013e32835a2159.
Groban, L., Wang, H., Machado, F. S., Trask, A. J., Kritchevsky, S. B., Ferrario, C. M., & Diz, D. I. (2012). Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovascular endocrinology, 1(3), 49-58. https://doi.org/10.1097/XCE.0b013e32835a2159
Groban, Leanne, et al. "Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats." Cardiovascular endocrinology vol. 1,3 (2012): 49-58. doi: https://doi.org/10.1097/XCE.0b013e32835a2159
Groban L, Wang H, Machado FS, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI. Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovasc Endocrinol. 2012 Sep 01;1(3):49-58. doi: 10.1097/XCE.0b013e32835a2159. PMID: 23795309; PMCID: PMC3685869.
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Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes.

International journal of nephrology and renovascular disease

Terami T, Wada J, Inoue K, Nakatsuka A, Ogawa D, Teshigawara S, Murakami K, Katayama A, Eguchi J, Makino H.
PMID: 24174882
Int J Nephrol Renovasc Dis. 2013 Oct 22;6:233-40. doi: 10.2147/IJNRD.S51829. eCollection 2013.

PURPOSE: Urinary angiotensinogen has been reported as a marker for the activation of intrarenal renin-angiotensin system (RAS) in various kidney diseases. To investigate the importance of urinary angiotensinogen in diabetic nephropathy, we compared the urinary levels of angiotensinogen, albumin,...

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Terami T, Wada J, Inoue K, et al. Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes. Int J Nephrol Renovasc Dis. 2013;6:233-40doi: 10.2147/IJNRD.S51829.
Terami, T., Wada, J., Inoue, K., Nakatsuka, A., Ogawa, D., Teshigawara, S., Murakami, K., Katayama, A., Eguchi, J., & Makino, H. (2013). Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes. International journal of nephrology and renovascular disease, 6233-40. https://doi.org/10.2147/IJNRD.S51829
Terami, Takahiro, et al. "Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes." International journal of nephrology and renovascular disease vol. 6 (2013): 233-40. doi: https://doi.org/10.2147/IJNRD.S51829
Terami T, Wada J, Inoue K, Nakatsuka A, Ogawa D, Teshigawara S, Murakami K, Katayama A, Eguchi J, Makino H. Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes. Int J Nephrol Renovasc Dis. 2013 Oct 22;6:233-40. doi: 10.2147/IJNRD.S51829. eCollection 2013. PMID: 24174882; PMCID: PMC3808213.
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PP025. Measurement of the activity of the circulating and intrarenal renin-angiotensin system (iRAS) in pregnant and non-pregnant subjects.

Pregnancy hypertension

Lumbers E, Pringle K, Sykes S, Weatherall L, Clausen D, Rae K, Smith R.
PMID: 26105881
Pregnancy Hypertens. 2013 Apr;3(2):76. doi: 10.1016/j.preghy.2013.04.053. Epub 2013 Jun 06.

OBJECTIVES: To see if urinary angiotensinogen (uAGT)/creatinine and other urinary components of the RAS could be used to detect renal disease in pregnancy, as renal disease predisposes to preeclampsia.METHODS: Plasma and urinary prorenin, ACE and AGT (iRAS) were measured...

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Lumbers E, Pringle K, Sykes S, et al. PP025. Measurement of the activity of the circulating and intrarenal renin-angiotensin system (iRAS) in pregnant and non-pregnant subjects. Pregnancy Hypertens. 2013;3(2):76doi: 10.1016/j.preghy.2013.04.053.
Lumbers, E., Pringle, K., Sykes, S., Weatherall, L., Clausen, D., Rae, K., & Smith, R. (2013). PP025. Measurement of the activity of the circulating and intrarenal renin-angiotensin system (iRAS) in pregnant and non-pregnant subjects. Pregnancy hypertension, 3(2), 76. https://doi.org/10.1016/j.preghy.2013.04.053
Lumbers, Eugenie, et al. "PP025. Measurement of the activity of the circulating and intrarenal renin-angiotensin system (iRAS) in pregnant and non-pregnant subjects." Pregnancy hypertension vol. 3,2 (2013): 76. doi: https://doi.org/10.1016/j.preghy.2013.04.053
Lumbers E, Pringle K, Sykes S, Weatherall L, Clausen D, Rae K, Smith R. PP025. Measurement of the activity of the circulating and intrarenal renin-angiotensin system (iRAS) in pregnant and non-pregnant subjects. Pregnancy Hypertens. 2013 Apr;3(2):76. doi: 10.1016/j.preghy.2013.04.053. Epub 2013 Jun 06. PMID: 26105881.
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Angiotensin Receptors: Structure, Function, Signaling and Clinical Applications.

Journal of cell signaling

Singh KD, Karnik SS.
PMID: 27512731
J Cell Signal. 2016 Jun;1(2). doi: 10.4172/jcs.1000111. Epub 2016 Apr 08.

Angiotensinogen - a serpin family protein predominantly produced by the liver is systematically processed by proteases of the Renin Angiotensin system (RAS) generating hormone peptides. Specific cell surface receptors for at least three distinct angiotensin peptides produce distinct cellular...

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Singh KD, Karnik SS. Angiotensin Receptors: Structure, Function, Signaling and Clinical Applications. J Cell Signal. 2016;1(2)doi: 10.4172/jcs.1000111.
Singh, K. D., & Karnik, S. S. (2016). Angiotensin Receptors: Structure, Function, Signaling and Clinical Applications. Journal of cell signaling, 1(2), . https://doi.org/10.4172/jcs.1000111
Singh, Khuraijam Dhanachandra, and Karnik, Sadashiva S. "Angiotensin Receptors: Structure, Function, Signaling and Clinical Applications." Journal of cell signaling vol. 1,2 (2016). doi: https://doi.org/10.4172/jcs.1000111
Singh KD, Karnik SS. Angiotensin Receptors: Structure, Function, Signaling and Clinical Applications. J Cell Signal. 2016 Jun;1(2). doi: 10.4172/jcs.1000111. Epub 2016 Apr 08. PMID: 27512731; PMCID: PMC4976824.
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Angiotensin-(1-7): A Novel Peptide to Treat Hypertension and Nephropathy in Diabetes?.

Journal of diabetes & metabolism

Padda RS, Shi Y, Lo CS, Zhang SL, Chan JS.
PMID: 26793405
J Diabetes Metab. 2015 Oct 14;6(10). doi: 10.4172/2155-6156.1000615.

The renin-angiotensin system (RAS) plays a pivotal role in mammalian homeostasis physiology. The RAS can be delineated into a classical RAS (the pressor arm) including angiotensinogen (Agt), renin, angiotensin-converting enzyme (ACE), angiotensin II (Ang II) and angiotensin type 1...

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Padda RS, Shi Y, Lo CS, et al. Angiotensin-(1-7): A Novel Peptide to Treat Hypertension and Nephropathy in Diabetes?. J Diabetes Metab. 2015;6(10)doi: 10.4172/2155-6156.1000615.
Padda, R. S., Shi, Y., Lo, C. S., Zhang, S. L., & Chan, J. S. (2015). Angiotensin-(1-7): A Novel Peptide to Treat Hypertension and Nephropathy in Diabetes?. Journal of diabetes & metabolism, 6(10), . https://doi.org/10.4172/2155-6156.1000615
Padda, Ranjit Singh, et al. "Angiotensin-(1-7): A Novel Peptide to Treat Hypertension and Nephropathy in Diabetes?." Journal of diabetes & metabolism vol. 6,10 (2015). doi: https://doi.org/10.4172/2155-6156.1000615
Padda RS, Shi Y, Lo CS, Zhang SL, Chan JS. Angiotensin-(1-7): A Novel Peptide to Treat Hypertension and Nephropathy in Diabetes?. J Diabetes Metab. 2015 Oct 14;6(10). doi: 10.4172/2155-6156.1000615. PMID: 26793405; PMCID: PMC4716813.
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Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population.

Clinical hypertension

Purkait P, Halder K, Thakur S, Ghosh Roy A, Raychaudhuri P, Bhattacharya S, Sarkar BN, Naidu JM.
PMID: 28361007
Clin Hypertens. 2017 Mar 29;23:12. doi: 10.1186/s40885-017-0069-x. eCollection 2017.

BACKGROUND: Angiotensinogen (AGT) enzyme comprises a vital module of RAAS system that effectively controls the blood pressure and related cardiovascular functions. Ample association studies have reported the importance of AGT variants in cardiovascular and non-cardiovascular adversities. But lately, owing...

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Purkait P, Halder K, Thakur S, et al. Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population. Clin Hypertens. 2017;23:12doi: 10.1186/s40885-017-0069-x.
Purkait, P., Halder, K., Thakur, S., Ghosh Roy, A., Raychaudhuri, P., Bhattacharya, S., Sarkar, B. N., & Naidu, J. M. (2017). Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population. Clinical hypertension, 2312. https://doi.org/10.1186/s40885-017-0069-x
Purkait, Pulakes, et al. "Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population." Clinical hypertension vol. 23 (2017): 12. doi: https://doi.org/10.1186/s40885-017-0069-x
Purkait P, Halder K, Thakur S, Ghosh Roy A, Raychaudhuri P, Bhattacharya S, Sarkar BN, Naidu JM. Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population. Clin Hypertens. 2017 Mar 29;23:12. doi: 10.1186/s40885-017-0069-x. eCollection 2017. PMID: 28361007; PMCID: PMC5371191.
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A local renal renin-angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats.

Diabetes, metabolic syndrome and obesity : targets and therapy

Tojo A, Kinugasa S, Fujita T, Wilcox CS.
PMID: 26848273
Diabetes Metab Syndr Obes. 2016 Jan 18;9:1-10. doi: 10.2147/DMSO.S91245. eCollection 2016.

The mechanism of activation of local renal renin-angiotensin system (RAS) has not been clarified in diabetes mellitus (DM). We hypothesized that the local renal RAS will be activated via increased glomerular filtration and tubular uptake of prorenin and angiotensinogen...

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Tojo A, Kinugasa S, Fujita T, et al. A local renal renin-angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats. Diabetes Metab Syndr Obes. 2016;9:1-10doi: 10.2147/DMSO.S91245.
Tojo, A., Kinugasa, S., Fujita, T., & Wilcox, C. S. (2016). A local renal renin-angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats. Diabetes, metabolic syndrome and obesity : targets and therapy, 91-10. https://doi.org/10.2147/DMSO.S91245
Tojo, Akihiro, et al. "A local renal renin-angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats." Diabetes, metabolic syndrome and obesity : targets and therapy vol. 9 (2016): 1-10. doi: https://doi.org/10.2147/DMSO.S91245
Tojo A, Kinugasa S, Fujita T, Wilcox CS. A local renal renin-angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats. Diabetes Metab Syndr Obes. 2016 Jan 18;9:1-10. doi: 10.2147/DMSO.S91245. eCollection 2016. PMID: 26848273; PMCID: PMC4723098.
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PP039. ETK/BMX and renin-angiotensin system (RAS) components are differentially expressed in renal tissue in both normal and preeclamptic pregnancy.

Pregnancy hypertension

Strevens H, Kurlak L, Mistry H, Hansen A, Broughton Pipkin F.
PMID: 26105897
Pregnancy Hypertens. 2013 Apr;3(2):81. doi: 10.1016/j.preghy.2013.04.066. Epub 2013 Jun 06.

INTRODUCTION: Renal ETK/BMX activity is reduced in preeclampsia. Systemic RAS has been studied in preeclampsia; the renal RAS has not. None of the proteins in either pathway have previously been located in renal tissue from human pregnancy.OBJECTIVES: To determine...

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Strevens H, Kurlak L, Mistry H, et al. PP039. ETK/BMX and renin-angiotensin system (RAS) components are differentially expressed in renal tissue in both normal and preeclamptic pregnancy. Pregnancy Hypertens. 2013;3(2):81doi: 10.1016/j.preghy.2013.04.066.
Strevens, H., Kurlak, L., Mistry, H., Hansen, A., & Broughton Pipkin, F. (2013). PP039. ETK/BMX and renin-angiotensin system (RAS) components are differentially expressed in renal tissue in both normal and preeclamptic pregnancy. Pregnancy hypertension, 3(2), 81. https://doi.org/10.1016/j.preghy.2013.04.066
Strevens, Helena, et al. "PP039. ETK/BMX and renin-angiotensin system (RAS) components are differentially expressed in renal tissue in both normal and preeclamptic pregnancy." Pregnancy hypertension vol. 3,2 (2013): 81. doi: https://doi.org/10.1016/j.preghy.2013.04.066
Strevens H, Kurlak L, Mistry H, Hansen A, Broughton Pipkin F. PP039. ETK/BMX and renin-angiotensin system (RAS) components are differentially expressed in renal tissue in both normal and preeclamptic pregnancy. Pregnancy Hypertens. 2013 Apr;3(2):81. doi: 10.1016/j.preghy.2013.04.066. Epub 2013 Jun 06. PMID: 26105897.
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Recent Advances in Molecular Genetics of Cardiovascular Disorders - Implications for Atherosclerosis and Diseases of Cellular Lipid Metabolism.

Pathology oncology research : POR

Schmitz G, Aslanidis C, Lackner KJ.
PMID: 11173654
Pathol Oncol Res. 1998;4(2):153-161.

Two developments in molecular genetics will profoundly influence our understanding and the diagnosis of cardiovascular disorders. First, the identification of genes responsible for monogenic and polygenic traits by analysis of e.g. large pedigrees and affected sib pairs provides invaluable...

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Schmitz G, Aslanidis C, Lackner KJ. Recent Advances in Molecular Genetics of Cardiovascular Disorders - Implications for Atherosclerosis and Diseases of Cellular Lipid Metabolism. Pathol Oncol Res. 1998;4(2):153-161
Schmitz, G., Aslanidis, C., & Lackner, K. J. (1998). Recent Advances in Molecular Genetics of Cardiovascular Disorders - Implications for Atherosclerosis and Diseases of Cellular Lipid Metabolism. Pathology oncology research : POR, 4(2), 153-161.
Schmitz, Gerd, et al. "Recent Advances in Molecular Genetics of Cardiovascular Disorders - Implications for Atherosclerosis and Diseases of Cellular Lipid Metabolism." Pathology oncology research : POR vol. 4,2 (1998): 153-161.
Schmitz G, Aslanidis C, Lackner KJ. Recent Advances in Molecular Genetics of Cardiovascular Disorders - Implications for Atherosclerosis and Diseases of Cellular Lipid Metabolism. Pathol Oncol Res. 1998;4(2):153-161. PMID: 11173654.
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The adipose renin-angiotensin system modulates systemic markers of insulin sensitivity and activates the intrarenal renin-angiotensin system.

Journal of biomedicine & biotechnology

Kim S, Soltani-Bejnood M, Quignard-Boulange A, Massiera F, Teboul M, Ailhaud G, Kim JH, Moustaid-Moussa N, Voy BH.
PMID: 17489015
J Biomed Biotechnol. 2006;2006(5):27012. doi: 10.1155/JBB/2006/27012.

BACKGROUND: The adipose tissue renin-angiotensin system (RAS) contributes to regulation of fat mass and may also impact systemic functions such as blood pressure and metabolism.METHODS AND RESULTS: A panel of mouse models including mice lacking angiotensinogen, Agt (Agt-KO), mice...

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Kim S, Soltani-Bejnood M, Quignard-Boulange A, et al. The adipose renin-angiotensin system modulates systemic markers of insulin sensitivity and activates the intrarenal renin-angiotensin system. J Biomed Biotechnol. 2006;2006(5):27012doi: 10.1155/JBB/2006/27012.
Kim, S., Soltani-Bejnood, M., Quignard-Boulange, A., Massiera, F., Teboul, M., Ailhaud, G., Kim, J. H., Moustaid-Moussa, N., & Voy, B. H. (2006). The adipose renin-angiotensin system modulates systemic markers of insulin sensitivity and activates the intrarenal renin-angiotensin system. Journal of biomedicine & biotechnology, 2006(5), 27012. https://doi.org/10.1155/JBB/2006/27012
Kim, Suyeon, et al. "The adipose renin-angiotensin system modulates systemic markers of insulin sensitivity and activates the intrarenal renin-angiotensin system." Journal of biomedicine & biotechnology vol. 2006,5 (2006): 27012. doi: https://doi.org/10.1155/JBB/2006/27012
Kim S, Soltani-Bejnood M, Quignard-Boulange A, Massiera F, Teboul M, Ailhaud G, Kim JH, Moustaid-Moussa N, Voy BH. The adipose renin-angiotensin system modulates systemic markers of insulin sensitivity and activates the intrarenal renin-angiotensin system. J Biomed Biotechnol. 2006;2006(5):27012. doi: 10.1155/JBB/2006/27012. PMID: 17489015; PMCID: PMC1698261.
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