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Showing 1 to 12 of 15 entries
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Risk of Diabetes in Patients with Long-Standing Graves' Disease: A Longitudinal Study.

Endocrinology and metabolism (Seoul, Korea)

Song E, Koo MJ, Noh E, Hwang SY, Park MJ, Kim JA, Roh E, Choi KM, Baik SH, Cho GJ, Yoo HJ.
PMID: 34915605
Endocrinol Metab (Seoul). 2021 Dec 16; doi: 10.3803/EnM.2021.1251. Epub 2021 Dec 16.

BACKGROUND: The detrimental effects of excessive thyroid hormone on glucose metabolism have been widely investigated. However, the risk of diabetes in patients with long-standing hyperthyroidism, especially according to treatment modality, remains uncertain, with few longitudinal studies.METHODS: The risk of...

Thyrotoxic Periodic Paralysis-A Misleading Challenge in the Emergency Department.

Diagnostics (Basel, Switzerland)

Bilha S, Mitu O, Teodoriu L, Haba C, Preda C.
PMID: 32443393
Diagnostics (Basel). 2020 May 18;10(5). doi: 10.3390/diagnostics10050316.

Despite its' life-threatening potential due to cardiac severe dysrhythmia in the context of severe hypokalemia, thyrotoxic periodic paralysis (TPP) often goes unrecognized. Although classically confined to young Asian men, it can occur irrespective of age, sex, and race. We...

Antithyroid Drug Treatment in Graves' Disease.

Endocrinology and metabolism (Seoul, Korea)

Chung JH.
PMID: 34130446
Endocrinol Metab (Seoul). 2021 Jun;36(3):491-499. doi: 10.3803/EnM.2021.1070. Epub 2021 Jun 16.

Graves' disease is associated with thyrotropin (TSH) receptor stimulating antibody, for which there is no therapeutic agent. This disease is currently treated through inhibition of thyroid hormone synthesis or destruction of the thyroid gland. Recurrence after antithyroid drug (ATD)...

Henoch-Schönlein Purpura (IgA Vasculitis) in Association with Thyrotoxicosis.

Case reports in endocrinology

Sanjari M, Shakibi M, Safavi M.
PMID: 34123438
Case Rep Endocrinol. 2021 May 22;2021:6669653. doi: 10.1155/2021/6669653. eCollection 2021.

Graves' disease is the most common cause of hyperthyroidism, which is characterized by thyroid antibodies and the following clinical manifestations: goiter, ophthalmopathy, and pretibial myxedema. On the other hand, Henoch-Schönlein purpura is an IgA-mediated small-vessel vasculitis. Review of the...

A comparison of cultured rat FRTL-5 and porcine thyroid cells for predicting the thyroid toxicity of xenobiotics.

Toxicology in vitro : an international journal published in association with BIBRA

Atterwill CK, Fowler KF.
PMID: 20702196
Toxicol In Vitro. 1990;4(4):369-74. doi: 10.1016/0887-2333(90)90082-5.

Two commonly used cell culture systems are currently available for testing the effects of xenobiotics on thyroid cell function and growth. These are the rat FRTL-5 thyroid cell line and the primary, cultured porcine thyrocyte. Both systems have inherent...

Characteristics of Korean Patients with Antithyroid Drug-Induced Agranulocytosis: A Multicenter Study in Korea.

Endocrinology and metabolism (Seoul, Korea)

Kim HK, Yoon JH, Jeon MJ, Kim TY, Shong YK, Lee MJ, Kim BH, Kim IJ, Joung JY, Kim SW, Chung JH, Kang HC.
PMID: 26394729
Endocrinol Metab (Seoul). 2015 Dec;30(4):475-80. doi: 10.3803/EnM.2015.30.4.475. Epub 2015 Sep 22.

BACKGROUND: Antithyroid drugs (ATDs) can lead to the development of agranulocytosis, which is the most serious adverse effect. Characteristics of ATD-induced agranulocytosis (AIA) have seldom been reported due to the rarity. In this study, we characterized the clinical features...

Antithyroid drug induced syndrome that lies in between ANCA vasculitis and lupus-like syndrome in a 40-year-old female with Graves' disease under methimazole therapy: A Case report.

Mediterranean journal of rheumatology

Nikitopoulou E, Gazi S.
PMID: 32185299
Mediterr J Rheumatol. 2018 Mar 19;29(1):52-54. doi: 10.31138/mjr.29.1.52. eCollection 2018 Mar.

We report the case of a 40-year-old Greek female with symptoms of polyarthritis, pruritic rash and positive p-ANCA antibodies, undergoing treatment with Methimazole therapy for Graves' disease. The rash and the arthritis symptoms promptly disappeared after withdrawal of methimazole,...

Predicting relapse of Graves' disease following treatment with antithyroid drugs.

Experimental and therapeutic medicine

Liu L, Lu H, Liu Y, Liu C, Xun C.
PMID: 27073464
Exp Ther Med. 2016 Apr;11(4):1453-1458. doi: 10.3892/etm.2016.3058. Epub 2016 Feb 09.

The aim of the present study was to monitor long term antithyroid drug treatments and to identify prognostic factors for Graves' disease (GD). A total of 306 patients with GD who were referred to the Endocrinology Clinic at Weifang...

Surgical management of an atypical presentation of a thyroid storm.

International journal of endocrinology and metabolism

Aulet RM, Wein RO, Siegel RD.
PMID: 24782903
Int J Endocrinol Metab. 2014 Apr 01;12(2):e13539. doi: 10.5812/ijem.13539. eCollection 2014 Apr.

INTRODUCTION: Thyroid storm is a rare complication of Graves' disease that can carry a poor prognosis. In order to prevent major complications, thyroid storm must be quickly identified in patients and treatment must be promptly implemented. Medical treatment is...

An overview on the proposed mechanisms of antithyroid drugs-induced liver injury.

Advanced pharmaceutical bulletin

Heidari R, Niknahad H, Jamshidzadeh A, Eghbal MA, Abdoli N.
PMID: 25789213
Adv Pharm Bull. 2015 Mar;5(1):1-11. doi: 10.5681/apb.2015.001. Epub 2015 Mar 05.

Drug-induced liver injury (DILI) is a major problem for pharmaceutical industry and drug development. Mechanisms of DILI are many and varied. Elucidating the mechanisms of DILI will allow clinicians to prevent liver failure, need for liver transplantation, and death...

Hemodynamic Instability during Thyroidectomy in Graves' Disease.

Journal of investigative surgery : the official journal of the Academy of Surgical Research

Acar S, Ercetin C, Sahbaz NA, Tutal F, Yapalak Y, Cosan F, Erbil Y.
PMID: 33908335
J Invest Surg. 2021 Apr 28;1-5. doi: 10.1080/08941939.2021.1914785. Epub 2021 Apr 28.

BACKGROUND: The aim of this study was to investigate the changes in vital signs and hemodynamic status that occur in patients during the intraoperative course of thyroidectomy in Graves' Disease (GD).METHODS: A total of 71 patients were included in...

Methimazole-Induced Aplastic Anemia with Concomitant Hepatitis in a Young Filipina with Graves' Disease.

Journal of the ASEAN Federation of Endocrine Societies

Wijaya N, Ong-Ramos C.
PMID: 33442144
J ASEAN Fed Endocr Soc. 2019;34(1):99-102. doi: 10.15605/jafes.034.01.16. Epub 2019 May 21.

A 34-year-old female Filipino with Graves' disease on methimazole came in due to fever, sore throat and jaundice. She was initially diagnosed with methimazole-induced agranulocytosis and drug-induced liver injury. She was treated with intravenous broad-spectrum antibiotic and granulocyte colony...

Showing 1 to 12 of 15 entries