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Showing 1 to 12 of 68 entries
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World economy: how much can we afford to spend on medical research?.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Arsenis GD.
PMID: 3148336
Biomed Pharmacother. 1988;42(10):635-8.

No abstract available.

Characterization of Small Isotropic Bicelles with Various Compositions.

Langmuir : the ACS journal of surfaces and colloids

Mineev KS, Nadezhdin KD, Goncharuk SA, Arseniev AS.
PMID: 27285636
Langmuir. 2016 Jul 05;32(26):6624-37. doi: 10.1021/acs.langmuir.6b00867. Epub 2016 Jun 22.

Structural studies of membrane proteins are of great importance and interest, with solution and solid state NMR spectroscopy being very promising tools for that task. However, such investigations are hindered by a number of obstacles, and in the first...

Phase Transitions in Small Isotropic Bicelles.

Langmuir : the ACS journal of surfaces and colloids

Kot EF, Goncharuk SA, Arseniev AS, Mineev KS.
PMID: 29486112
Langmuir. 2018 Mar 20;34(11):3426-3437. doi: 10.1021/acs.langmuir.7b03610. Epub 2018 Mar 06.

Isotropic phospholipid bicelles are one of the most prospective membrane mimetics for the structural studies of membrane proteins in solution. Recent works provided an almost full set of data regarding the properties of isotropic bicelles; however, one major aspect...

New strategies for treatment of Candida vaginal infections.

Revista iberoamericana de micologia

Magliani W, Conti S, Salati A, Arseni S, Frazzi R, Ravanetti L, Polonelli L.
PMID: 12825992
Rev Iberoam Micol. 2002 Sep;19(3):144-8.

New strategies for treatment of vaginal candidiasis have been recently exploited, due to widespread occurrence of this disease, in particular as recurrent infections, limitations of safe and efficacious antifungals as well as the lack of reliable preventative approaches. In...

Extrinsic apoptotic pathways: a new potential "target" for more sufficient therapy in a case of cutaneous anaplastic large cd30+ alk-T-cell lymphoma.

Indian journal of dermatology

Tchernev G, Georgi T, Cardoso JC, Carlos CJ, Arseniev L, Lubomir A, Okamoto H, Hiroyuki O.
PMID: 21572802
Indian J Dermatol. 2011 Jan;56(1):87-91. doi: 10.4103/0019-5154.77563.

The primary cutaneous T-cell lymphomas (CTCL) represent a clonal T-lymphocyte proliferation infiltrating the skin. CD30(+)T-cell lymphomas present clinically as nodules with a diameter between 1 and 15 cm, mostly in elderly patients. The role of the CD30 molecule in...

N-terminal fusion tags for effective production of g-protein-coupled receptors in bacterial cell-free systems.

Acta naturae

Lyukmanova EN, Shenkarev ZO, Khabibullina NF, Kulbatskiy DS, Shulepko MA, Petrovskaya LE, Arseniev AS, Dolgikh DA, Kirpichnikov MP.
PMID: 23346380
Acta Naturae. 2012 Oct;4(4):58-64.

G-protein-coupled receptors (GPCR) constitute one of the biggest families of membrane proteins. In spite of the fact that they are highly relevant to pharmacy, they have remained poorly explored. One of the main bottlenecks encountered in structural-functional studies of...

Beilstein journal of organic chemistry

Deev SL, Paramonov AS, Shestakova TS, Khalymbadzha IA, Chupakhin ON, Subbotina JO, Eltsov OS, Slepukhin PA, Rusinov VL, Arseniev AS, Shenkarev ZO.
PMID: 29259663
Beilstein J Org Chem. 2017 Nov 29;13:2535-2548. doi: 10.3762/bjoc.13.250. eCollection 2017.

Determining the accurate chemical structures of synthesized compounds is essential for biomedical studies and computer-assisted drug design. The unequivocal determination of N-adamantylation or N-arylation site(s) in nitrogen-rich heterocycles, characterized by a low density of hydrogen atoms, using NMR methods...

Insights into deep decline of As(III) leachability induced by As(III) partial oxidation during lime stabilization of As-Ca sludge.

Journal of hazardous materials

Wang X, Zhang Y, Zhang H, Wu X, Ding J, Wang L, Chen J, Wu X, Xiao J, Wang L, Tsang DCW, Crittenden JC.
PMID: 34736207
J Hazard Mater. 2022 Feb 15;424:127575. doi: 10.1016/j.jhazmat.2021.127575. Epub 2021 Oct 24.

The enhancing effect of As(III) oxidation on As stabilization by lime is routinely attributed to the lower solubility of Ca arsenates than Ca arsenites. However, this routine explanation is insufficient for the scenario of As(III) partial oxidation, in which...

Backbone dynamics of (1-71)- and (1-36)bacterioopsin studied by two-dimensional (1)H- (15)N NMR spectroscopy.

Journal of biomolecular NMR

Orekhov VY, Pervushin KV, Korzhnev DM, Arseniev AS.
PMID: 22910799
J Biomol NMR. 1995 Sep;6(2):113-22. doi: 10.1007/BF00211774.

The backbone dynamics of uniformly (15)N-labelled fragments (residues 1-71 and 1-36) of bacterioopsin, solubilized in two media (methanol-chloroform (1:1), 0.1 M (2)HCO(2)NH(4), or SDS micelles) have been investigated using 2D proton-detected heteronuclear (1)H-(15)N NMR spectroscopy at two spectrometer frequencies,...

Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn.

Communications biology

Lushpa VA, Goncharuk MV, Lin C, Zalevsky AO, Talyzina IA, Luginina AP, Vakhrameev DD, Shevtsov MB, Goncharuk SA, Arseniev AS, Borshchevskiy VI, Wang X, Mineev KS.
PMID: 34429510
Commun Biol. 2021 Aug 24;4(1):1003. doi: 10.1038/s42003-021-02532-0.

Toll-like receptors (TLRs) play an important role in the innate immune response. While a lot is known about the structures of their extracellular parts, many questions are still left unanswered, when the structural basis of TLR activation is analyzed...

Functionality and Cell Senescence of CD4/ CD8-Selected CD20 CAR T Cells Manufactured Using the Automated CliniMACS Prodigy® Platform.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

Aleksandrova K, Leise J, Priesner C, Melk A, Kubaink F, Abken H, Hombach A, Aktas M, Essl M, Bürger I, Kaiser A, Rauser G, Jurk M, Goudeva L, Glienke W, Arseniev L, Esser R, Köhl U.
PMID: 31244581
Transfus Med Hemother. 2019 Feb;46(1):47-54. doi: 10.1159/000495772. Epub 2019 Feb 04.

Clinical studies using autologous CAR T cells have achieved spectacular remissions in refractory CD19+ B cell leukaemia, however some of the patient treatments with CAR T cells failed. Beside the heterogeneity of leukaemia, the distribution and senescence of the...

Reference correlations for the thermal conductivity of liquid copper, gallium, indium, iron, lead, nickel and tin.

High temperatures - high pressures

Assael MJ, Chatzimichailidis A, Antoniadis KD, Wakeham WA, Huber ML, Fukuyama H.
PMID: 29353915
High Temp High Press. 2017;46(6):391-416.

The available experimental data for the thermal conductivity of liquid copper, gallium, indium, iron, lead, nickel, and tin has been critically examined with the intention of establishing thermal conductivity reference correlations. All experimental data have been categorized into primary...

Showing 1 to 12 of 68 entries