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Showing 1 to 4 of 4 entries
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SBpipe: a collection of pipelines for automating repetitive simulation and analysis tasks.

BMC systems biology

Dalle Pezze P, Le Novère N.
PMID: 28395655
BMC Syst Biol. 2017 Apr 10;11(1):46. doi: 10.1186/s12918-017-0423-3.

BACKGROUND: The rapid growth of the number of mathematical models in Systems Biology fostered the development of many tools to simulate and analyse them. The reliability and precision of these tasks often depend on multiple repetitions and they can...

Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK.

Heliyon

Hey F, Andreadi C, Noble C, Patel B, Jin H, Kamata T, Straatman K, Luo J, Balmanno K, Jones DTW, Collins VP, Cook SJ, Caunt CJ, Pritchard C.
PMID: 30603699
Heliyon. 2018 Dec 20;4(12):e01065. doi: 10.1016/j.heliyon.2018.e01065. eCollection 2018 Dec.

BRAF is a cytoplasmic protein kinase, which activates the MEK-ERK signalling pathway. Deregulation of the pathway is associated with the presence of

The promises of quantitative systems pharmacology modelling for drug development.

Computational and structural biotechnology journal

Knight-Schrijver VR, Chelliah V, Cucurull-Sanchez L, Le Novère N.
PMID: 27761201
Comput Struct Biotechnol J. 2016 Sep 23;14:363-370. doi: 10.1016/j.csbj.2016.09.002. eCollection 2016.

Recent growth in annual new therapeutic entity (NTE) approvals by the U.S. Food and Drug Administration (FDA) suggests a positive trend in current research and development (R&D) output. Prior to this, the cost of each NTE was considered to...

Promoting Coordinated Development of Community-Based Information Standards for Modeling in Biology: The COMBINE Initiative.

Frontiers in bioengineering and biotechnology

Hucka M, Nickerson DP, Bader GD, Bergmann FT, Cooper J, Demir E, Garny A, Golebiewski M, Myers CJ, Schreiber F, Waltemath D, Le Novère N.
PMID: 25759811
Front Bioeng Biotechnol. 2015 Feb 24;3:19. doi: 10.3389/fbioe.2015.00019. eCollection 2015.

The Computational Modeling in Biology Network (COMBINE) is a consortium of groups involved in the development of open community standards and formats used in computational modeling in biology. COMBINE's aim is to act as a coordinator, facilitator, and resource...

Showing 1 to 4 of 4 entries