Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 13 entries
Sorted by: Best Match Show Resources per page
Erlotinib and Trametinib in Patients With .

JCO precision oncology

Luo J, Makhnin A, Tobi Y, Ahn L, Hayes SA, Iqbal A, Ng K, Arcila ME, Riely GJ, Kris MG, Yu HA.
PMID: 34250388
JCO Precis Oncol. 2021 Jan 11;5. doi: 10.1200/PO.20.00315. eCollection 2021.

Inhibition of the MEK/ERK pathway is critical for Bcl-2-like protein 11 (BIM)-mediated epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-induced apoptosis, and dysregulation of this pathway may be a mechanism of acquired resistance. Therefore, MEK inhibition with trametinib...

Cite
Luo J, Makhnin A, Tobi Y, et al. Erlotinib and Trametinib in Patients With . JCO Precis Oncol. 2021;5doi: 10.1200/PO.20.00315.
Luo, J., Makhnin, A., Tobi, Y., Ahn, L., Hayes, S. A., Iqbal, A., Ng, K., Arcila, M. E., Riely, G. J., Kris, M. G., & Yu, H. A. (2021). Erlotinib and Trametinib in Patients With . JCO precision oncology, 5. https://doi.org/10.1200/PO.20.00315
Luo, Jia, et al. "Erlotinib and Trametinib in Patients With ." JCO precision oncology vol. 5 (2021). doi: https://doi.org/10.1200/PO.20.00315
Luo J, Makhnin A, Tobi Y, Ahn L, Hayes SA, Iqbal A, Ng K, Arcila ME, Riely GJ, Kris MG, Yu HA. Erlotinib and Trametinib in Patients With . JCO Precis Oncol. 2021 Jan 11;5. doi: 10.1200/PO.20.00315. eCollection 2021. PMID: 34250388; PMCID: PMC8232136.
Copy Download .nbib Format: NLM
The effect of maternal high-fat-diet mediated oxidative stress on ovarian function in mice offspring.

Experimental and therapeutic medicine

Yan S, Wang F, Shi Q.
PMID: 33082867
Exp Ther Med. 2020 Dec;20(6):135. doi: 10.3892/etm.2020.9264. Epub 2020 Oct 02.

A maternal high-fat diet (HFD) has been shown to exert deleterious effects on fetal programming by impairing embryo growth, and exerts a long-term effect on the health of offspring. The present study aimed to evaluate the effect of a...

Cite
Yan S, Wang F, Shi Q. The effect of maternal high-fat-diet mediated oxidative stress on ovarian function in mice offspring. Exp Ther Med. 2020;20(6):135doi: 10.3892/etm.2020.9264.
Yan, S., Wang, F., & Shi, Q. (2020). The effect of maternal high-fat-diet mediated oxidative stress on ovarian function in mice offspring. Experimental and therapeutic medicine, 20(6), 135. https://doi.org/10.3892/etm.2020.9264
Yan, Shi, et al. "The effect of maternal high-fat-diet mediated oxidative stress on ovarian function in mice offspring." Experimental and therapeutic medicine vol. 20,6 (2020): 135. doi: https://doi.org/10.3892/etm.2020.9264
Yan S, Wang F, Shi Q. The effect of maternal high-fat-diet mediated oxidative stress on ovarian function in mice offspring. Exp Ther Med. 2020 Dec;20(6):135. doi: 10.3892/etm.2020.9264. Epub 2020 Oct 02. PMID: 33082867; PMCID: PMC7560541.
Copy Download .nbib Format: NLM
MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells.

Bioscience reports

Zhang YY, Xiong GY, Xie XX.
PMID: 33942856
Biosci Rep. 2021 Jun 25;41(6). doi: 10.1042/BSR20201397.

Radiation-induced hair cell injury is detrimental for human health but the underlying mechanism is not clear. MicroRNAs (miRNAs) have critical roles in various types of cellular biological processes. The present study investigated the role of miR-222 in the regulation...

Cite
Zhang YY, Xiong GY, Xie XX. MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells. Biosci Rep. 2021;41(6)doi: 10.1042/BSR20201397.
Zhang, Y. Y., Xiong, G. Y., & Xie, X. X. (2021). MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells. Bioscience reports, 41(6), . https://doi.org/10.1042/BSR20201397
Zhang, Yan-Yan, et al. "MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells." Bioscience reports vol. 41,6 (2021). doi: https://doi.org/10.1042/BSR20201397
Zhang YY, Xiong GY, Xie XX. MicroRNA-222 alleviates radiation-induced apoptosis by targeting BCL2L11 in cochlea hair cells. Biosci Rep. 2021 Jun 25;41(6). doi: 10.1042/BSR20201397. PMID: 33942856; PMCID: PMC8182987.
Copy Download .nbib Format: NLM
Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis.

BioMed research international

Lv F, Sun L, Yang Q, Pan Z, Zhang Y.
PMID: 34722761
Biomed Res Int. 2021 Oct 13;2021:3621828. doi: 10.1155/2021/3621828. eCollection 2021.

BACKGROUND: Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) is inevitable in EGFR-mutant non-small-cell lung cancer (NSCLC) patients. A germline 2903 bp deletion polymorphism of Bcl-2-like protein 11 (BIM) causes reduced expression of proapoptotic BH3-only BIM protein...

Cite
Lv F, Sun L, Yang Q, et al. Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis. Biomed Res Int. 2021;2021:3621828doi: 10.1155/2021/3621828.
Lv, F., Sun, L., Yang, Q., Pan, Z., & Zhang, Y. (2021). Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis. BioMed research international, 20213621828. https://doi.org/10.1155/2021/3621828
Lv, Fangfang, et al. "Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis." BioMed research international vol. 2021 (2021): 3621828. doi: https://doi.org/10.1155/2021/3621828
Lv F, Sun L, Yang Q, Pan Z, Zhang Y. Prognostic Value of BIM Deletion in EGFR-Mutant NSCLC Patients Treated with EGFR-TKIs: A Meta-Analysis. Biomed Res Int. 2021 Oct 13;2021:3621828. doi: 10.1155/2021/3621828. eCollection 2021. PMID: 34722761; PMCID: PMC8551980.
Copy Download .nbib Format: NLM
MicroRNA-367-3p suppresses sevoflurane-induced adult rat astrocyte apoptosis by targeting BCL2L11.

Experimental and therapeutic medicine

Xu D, Zhou C, Lin J, Cai W, Lin W.
PMID: 34815761
Exp Ther Med. 2022 Jan;23(1):9. doi: 10.3892/etm.2021.10931. Epub 2021 Oct 28.

The present study aimed to characterize the effect of microRNA (miR)-367-3p on sevoflurane anesthesia and elucidate the underlying mechanism. A total of 36 4-month-old adult Sprague-Dawley rats were divided into six groups. Sevoflurane was inhaled at concentrations of 0,...

Cite
Xu D, Zhou C, Lin J, et al. MicroRNA-367-3p suppresses sevoflurane-induced adult rat astrocyte apoptosis by targeting BCL2L11. Exp Ther Med. 2021;23(1):9doi: 10.3892/etm.2021.10931.
Xu, D., Zhou, C., Lin, J., Cai, W., & Lin, W. (2022). MicroRNA-367-3p suppresses sevoflurane-induced adult rat astrocyte apoptosis by targeting BCL2L11. Experimental and therapeutic medicine, 23(1), 9. https://doi.org/10.3892/etm.2021.10931
Xu, Deming, et al. "MicroRNA-367-3p suppresses sevoflurane-induced adult rat astrocyte apoptosis by targeting BCL2L11." Experimental and therapeutic medicine vol. 23,1 (2022): 9. doi: https://doi.org/10.3892/etm.2021.10931
Xu D, Zhou C, Lin J, Cai W, Lin W. MicroRNA-367-3p suppresses sevoflurane-induced adult rat astrocyte apoptosis by targeting BCL2L11. Exp Ther Med. 2022 Jan;23(1):9. doi: 10.3892/etm.2021.10931. Epub 2021 Oct 28. PMID: 34815761; PMCID: PMC8593860.
Copy Download .nbib Format: NLM
Histone deacetylase 9 inhibition upregulates microRNA-92a to repress the progression of intracranial aneurysm via silencing Bcl-2-like protein 11.

Journal of drug targeting

Cai Y, Huang D, Ma W, Wang M, Qin Q, Jiang Z, Liu M.
PMID: 33480300
J Drug Target. 2021 Aug;29(7):761-770. doi: 10.1080/1061186X.2021.1878365. Epub 2021 Feb 08.

OBJECTIVE: Histone deacetylases (HDACs) have been revealed to be involved in cerebrovascular diseases, while the role of HDAC9 in intracranial aneurysm (IA) remains seldom studied. We aim to explore the role of the HDAC9/microRNA-92a (miR-92a)/Bcl-2-like protein 11 (BCL2L11) axis...

Cite
Cai Y, Huang D, Ma W, et al. Histone deacetylase 9 inhibition upregulates microRNA-92a to repress the progression of intracranial aneurysm via silencing Bcl-2-like protein 11. J Drug Target. 2021;29(7):761-770doi: 10.1080/1061186X.2021.1878365.
Cai, Y., Huang, D., Ma, W., Wang, M., Qin, Q., Jiang, Z., & Liu, M. (2021). Histone deacetylase 9 inhibition upregulates microRNA-92a to repress the progression of intracranial aneurysm via silencing Bcl-2-like protein 11. Journal of drug targeting, 29(7), 761-770. https://doi.org/10.1080/1061186X.2021.1878365
Cai, Yang, et al. "Histone deacetylase 9 inhibition upregulates microRNA-92a to repress the progression of intracranial aneurysm via silencing Bcl-2-like protein 11." Journal of drug targeting vol. 29,7 (2021): 761-770. doi: https://doi.org/10.1080/1061186X.2021.1878365
Cai Y, Huang D, Ma W, Wang M, Qin Q, Jiang Z, Liu M. Histone deacetylase 9 inhibition upregulates microRNA-92a to repress the progression of intracranial aneurysm via silencing Bcl-2-like protein 11. J Drug Target. 2021 Aug;29(7):761-770. doi: 10.1080/1061186X.2021.1878365. Epub 2021 Feb 08. PMID: 33480300.
Copy Download .nbib Format: NLM
MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11.

Experimental and therapeutic medicine

Zhang H, Xue S, Feng Y, Shen J, Zhao J.
PMID: 32256723
Exp Ther Med. 2020 Apr;19(4):2467-2474. doi: 10.3892/etm.2020.8517. Epub 2020 Feb 11.

Numerous reports have shown that dysfunction of vascular smooth muscle cells (VSMCs) serves a critical function in the development of cardiovascular disease, including coronary heart disease (CHD). microRNAs (miRNAs/miRs) have been reported to play important roles in regulating the...

Cite
Zhang H, Xue S, Feng Y, et al. MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11. Exp Ther Med. 2020;19(4):2467-2474doi: 10.3892/etm.2020.8517.
Zhang, H., Xue, S., Feng, Y., Shen, J., & Zhao, J. (2020). MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11. Experimental and therapeutic medicine, 19(4), 2467-2474. https://doi.org/10.3892/etm.2020.8517
Zhang, Huanxin, et al. "MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11." Experimental and therapeutic medicine vol. 19,4 (2020): 2467-2474. doi: https://doi.org/10.3892/etm.2020.8517
Zhang H, Xue S, Feng Y, Shen J, Zhao J. MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11. Exp Ther Med. 2020 Apr;19(4):2467-2474. doi: 10.3892/etm.2020.8517. Epub 2020 Feb 11. PMID: 32256723; PMCID: PMC7086294.
Copy Download .nbib Format: NLM
Histone deacetylation, as opposed to promoter methylation, results in epigenetic .

Oncology letters

Zhao M, Zhang Y, Li J, Li X, Cheng N, Wang Q, Cai W, Zhao C, He Y, Chang J, Zhou C.
PMID: 29399169
Oncol Lett. 2018 Jan;15(1):1089-1096. doi: 10.3892/ol.2017.7411. Epub 2017 Nov 14.

Drug resistance remains a major challenge in epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) therapy. Bcl-2-like protein 11 (BIM), a B-cell lymphoma 2 family pro-apoptotic protein, is a prime target for specific anti-cancer therapeutics. However, the epigenetic regulation of...

Cite
Zhao M, Zhang Y, Li J, et al. Histone deacetylation, as opposed to promoter methylation, results in epigenetic . Oncol Lett. 2017;15(1):1089-1096doi: 10.3892/ol.2017.7411.
Zhao, M., Zhang, Y., Li, J., Li, X., Cheng, N., Wang, Q., Cai, W., Zhao, C., He, Y., Chang, J., & Zhou, C. (2018). Histone deacetylation, as opposed to promoter methylation, results in epigenetic . Oncology letters, 15(1), 1089-1096. https://doi.org/10.3892/ol.2017.7411
Zhao, Mingchuan, et al. "Histone deacetylation, as opposed to promoter methylation, results in epigenetic ." Oncology letters vol. 15,1 (2018): 1089-1096. doi: https://doi.org/10.3892/ol.2017.7411
Zhao M, Zhang Y, Li J, Li X, Cheng N, Wang Q, Cai W, Zhao C, He Y, Chang J, Zhou C. Histone deacetylation, as opposed to promoter methylation, results in epigenetic . Oncol Lett. 2018 Jan;15(1):1089-1096. doi: 10.3892/ol.2017.7411. Epub 2017 Nov 14. PMID: 29399169; PMCID: PMC5772734.
Copy Download .nbib Format: NLM
Erlotinib and Trametinib in Patients With .

JCO precision oncology

Luo J, Makhnin A, Tobi Y, Ahn L, Hayes SA, Iqbal A, Ng K, Arcila ME, Riely GJ, Kris MG, Yu HA.
PMID: 34250388
JCO Precis Oncol. 2021 Jan 11;5. doi: 10.1200/PO.20.00315. eCollection 2021.

Inhibition of the MEK/ERK pathway is critical for Bcl-2-like protein 11 (BIM)-mediated epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-induced apoptosis, and dysregulation of this pathway may be a mechanism of acquired resistance. Therefore, MEK inhibition with trametinib...

Cite
Luo J, Makhnin A, Tobi Y, et al. Erlotinib and Trametinib in Patients With . JCO Precis Oncol. 2021;5doi: 10.1200/PO.20.00315.
Luo, J., Makhnin, A., Tobi, Y., Ahn, L., Hayes, S. A., Iqbal, A., Ng, K., Arcila, M. E., Riely, G. J., Kris, M. G., & Yu, H. A. (2021). Erlotinib and Trametinib in Patients With . JCO precision oncology, 5. https://doi.org/10.1200/PO.20.00315
Luo, Jia, et al. "Erlotinib and Trametinib in Patients With ." JCO precision oncology vol. 5 (2021). doi: https://doi.org/10.1200/PO.20.00315
Luo J, Makhnin A, Tobi Y, Ahn L, Hayes SA, Iqbal A, Ng K, Arcila ME, Riely GJ, Kris MG, Yu HA. Erlotinib and Trametinib in Patients With . JCO Precis Oncol. 2021 Jan 11;5. doi: 10.1200/PO.20.00315. eCollection 2021. PMID: 34250388; PMCID: PMC8232136.
Copy Download .nbib Format: NLM
miR-17-5p attenuates kidney ischemia-reperfusion injury by inhibiting the PTEN and BIM pathways.

Annals of translational medicine

Ma M, Fu L, Jia Z, Zhong Q, Huang Z, Wang X, Fan Y, Lin T, Song T.
PMID: 34790751
Ann Transl Med. 2021 Oct;9(20):1545. doi: 10.21037/atm-21-4678.

BACKGROUND: Kidney ischemia-reperfusion (I/R) injury is an independent risk factor for delayed graft function after kidney transplantation with long-term graft survival deterioration. Previously, we found that the upregulated expression of miR-17-5p exerts a protective effect in kidney I/R injury,...

Cite
Ma M, Fu L, Jia Z, et al. miR-17-5p attenuates kidney ischemia-reperfusion injury by inhibiting the PTEN and BIM pathways. Ann Transl Med. 2021;9(20):1545doi: 10.21037/atm-21-4678.
Ma, M., Fu, L., Jia, Z., Zhong, Q., Huang, Z., Wang, X., Fan, Y., Lin, T., & Song, T. (2021). miR-17-5p attenuates kidney ischemia-reperfusion injury by inhibiting the PTEN and BIM pathways. Annals of translational medicine, 9(20), 1545. https://doi.org/10.21037/atm-21-4678
Ma, Ming, et al. "miR-17-5p attenuates kidney ischemia-reperfusion injury by inhibiting the PTEN and BIM pathways." Annals of translational medicine vol. 9,20 (2021): 1545. doi: https://doi.org/10.21037/atm-21-4678
Ma M, Fu L, Jia Z, Zhong Q, Huang Z, Wang X, Fan Y, Lin T, Song T. miR-17-5p attenuates kidney ischemia-reperfusion injury by inhibiting the PTEN and BIM pathways. Ann Transl Med. 2021 Oct;9(20):1545. doi: 10.21037/atm-21-4678. PMID: 34790751; PMCID: PMC8576735.
Copy Download .nbib Format: NLM
The Study of Apoptosis-inducing Effects of Three Pre-apoptotic Factors by Gallic Acid, Using Simulation Analysis and the Comet Assay Technique on the Prostatic Cancer Cell Line PC3.

The Malaysian journal of medical sciences : MJMS

Saffari-Chaleshtori J, Heidari-Sureshjani E, Moradi F, Jazi HM, Heidarian E.
PMID: 28951686
Malays J Med Sci. 2017 Aug;24(4):18-29. doi: 10.21315/mjms2017.24.4.3. Epub 2017 Aug 18.

BACKGROUND: In this study, we demonstrated the effects of the Gallic Acid (GA) molecule on the prostate cancer cells line PC3 using the comet assay (Alkaline electrophoresis) technique and its effects on some important apoptotic factors including BAD (Bcl-2-Associated...

Cite
Saffari-Chaleshtori J, Heidari-Sureshjani E, Moradi F, et al. The Study of Apoptosis-inducing Effects of Three Pre-apoptotic Factors by Gallic Acid, Using Simulation Analysis and the Comet Assay Technique on the Prostatic Cancer Cell Line PC3. Malays J Med Sci. 2017;24(4):18-29doi: 10.21315/mjms2017.24.4.3.
Saffari-Chaleshtori, J., Heidari-Sureshjani, E., Moradi, F., Jazi, H. M., & Heidarian, E. (2017). The Study of Apoptosis-inducing Effects of Three Pre-apoptotic Factors by Gallic Acid, Using Simulation Analysis and the Comet Assay Technique on the Prostatic Cancer Cell Line PC3. The Malaysian journal of medical sciences : MJMS, 24(4), 18-29. https://doi.org/10.21315/mjms2017.24.4.3
Saffari-Chaleshtori, Javad, et al. "The Study of Apoptosis-inducing Effects of Three Pre-apoptotic Factors by Gallic Acid, Using Simulation Analysis and the Comet Assay Technique on the Prostatic Cancer Cell Line PC3." The Malaysian journal of medical sciences : MJMS vol. 24,4 (2017): 18-29. doi: https://doi.org/10.21315/mjms2017.24.4.3
Saffari-Chaleshtori J, Heidari-Sureshjani E, Moradi F, Jazi HM, Heidarian E. The Study of Apoptosis-inducing Effects of Three Pre-apoptotic Factors by Gallic Acid, Using Simulation Analysis and the Comet Assay Technique on the Prostatic Cancer Cell Line PC3. Malays J Med Sci. 2017 Aug;24(4):18-29. doi: 10.21315/mjms2017.24.4.3. Epub 2017 Aug 18. PMID: 28951686; PMCID: PMC5609686.
Copy Download .nbib Format: NLM
The BCL2L11 deletion polymorphism is not associated with imatinib resistance in chronic myeloid leukemia patients: meta-analysis.

Oncotarget

Xu J, Gu J, Zhao Y, Meng H, Du L, Zhang R, Jiang H, Luo J.
PMID: 29228749
Oncotarget. 2017 Sep 22;8(58):99041-99048. doi: 10.18632/oncotarget.21154. eCollection 2017 Nov 17.

A common deletion polymorphism of the gene Bcl-2 like protein 11 (BCL2L11, BIM) has been reported to cause tyrosine kinase inhibitors (TKIs) resistance in several malignant tumors. However, the conclusions were not consistent in chronic myeloid leukemia (CML) individuals....

Cite
Xu J, Gu J, Zhao Y, et al. The BCL2L11 deletion polymorphism is not associated with imatinib resistance in chronic myeloid leukemia patients: meta-analysis. Oncotarget. 2017;8(58):99041-99048doi: 10.18632/oncotarget.21154.
Xu, J., Gu, J., Zhao, Y., Meng, H., Du, L., Zhang, R., Jiang, H., & Luo, J. (2017). The BCL2L11 deletion polymorphism is not associated with imatinib resistance in chronic myeloid leukemia patients: meta-analysis. Oncotarget, 8(58), 99041-99048. https://doi.org/10.18632/oncotarget.21154
Xu, Jinyun, et al. "The BCL2L11 deletion polymorphism is not associated with imatinib resistance in chronic myeloid leukemia patients: meta-analysis." Oncotarget vol. 8,58 (2017): 99041-99048. doi: https://doi.org/10.18632/oncotarget.21154
Xu J, Gu J, Zhao Y, Meng H, Du L, Zhang R, Jiang H, Luo J. The BCL2L11 deletion polymorphism is not associated with imatinib resistance in chronic myeloid leukemia patients: meta-analysis. Oncotarget. 2017 Sep 22;8(58):99041-99048. doi: 10.18632/oncotarget.21154. eCollection 2017 Nov 17. PMID: 29228749; PMCID: PMC5716789.
Copy Download .nbib Format: NLM
Showing 1 to 12 of 13 entries