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Showing 1 to 12 of 19 entries
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The effects of bromodeoxyuridine and bromouracil on regeneration inHydra.

Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen

Goyns MH, Stanisstreet M.
PMID: 28304714
Wilhelm Roux Arch Entwickl Mech Org. 1974 Jun;175(2):87-90. doi: 10.1007/BF00574294.

The effects on tentacle regeneration inHydra of two DNA-antimetabolites, bromouracil and bromodeoxyuridine, have been studied. Bromouracil inhibits tentacle regeneration inH. vulgaris andH. viridis; bromodeoxynridine inhibits tentacle regeneration inH. vulgaris but notH. viridis over the range of concentrations studied. Thus...

Photoreaction of DNA Containing 5-Halouracil and its Products.

Photochemistry and photobiology

Tashiro R, Sugiyama H.
PMID: 34543451
Photochem Photobiol. 2021 Sep 20; doi: 10.1111/php.13521. Epub 2021 Sep 20.

5-Halouracil, which is a DNA base analog in which the methyl group at the C5 position of thymine is replaced with a halogen atom, has been used in studies of DNA damage. In DNA strands, the uracil radical generated...

Cytosine Iminyl Radical (cytN.

The journal of physical chemistry. A

Kumar A, Sevilla MD.
PMID: 28586202
J Phys Chem A. 2017 Jun 29;121(25):4825-4829. doi: 10.1021/acs.jpca.7b04034. Epub 2017 Jun 16.

Halogen-substituted pyrimidines, such as 5-bromouracil and 5-iodouracil, have been used as radio therapeutic (RT) agents in cancer treatment. The radiosensitizing activity of 5-bromouracil is attributed to its reaction with electron which produce the highly reactive uracil-5-yl radical by dissociating...

Fragmentation of pure and hydrated clusters of 5Br-uracil by low energy carbon ions: observation of hydrated fragments.

Physical chemistry chemical physics : PCCP

Castrovilli MC, Markush P, Bolognesi P, Rousseau P, Maclot S, Cartoni A, Delaunay R, Domaracka A, Kočišek J, Huber BA, Avaldi L, Lima N.
PMID: 28657102
Phys Chem Chem Phys. 2017 Aug 02;19(30):19807-19814. doi: 10.1039/c7cp02233f.

The fragmentation of the isolated 5-bromouracil (5BrU) molecule and pure and nano-hydrated 5BrU clusters induced by low energy

Proton-coupled electron transfer is the dominant mechanism of reduction of haloacetates by the α-hydroxyethyl radical in aqueous media.

Physical chemistry chemical physics : PCCP

DŽeba I, Bonifačić M, Nikšić-Franjić I, Ljubić I.
PMID: 30033455
Phys Chem Chem Phys. 2018 Aug 01;20(30):19829-19840. doi: 10.1039/c8cp03544j.

The reaction systems of α-hydroxyalkyl radicals with halogenated organics in aqueous solutions are uniquely suited for studying the fundamentally important proton-coupled electron transfer (PCET) mechanism in competition with alternatives such as substitution, hydrogen abstraction, halogen atom abstraction etc. We...

[Effect of inhibitors of DNA-, RNA-, and protein synthesis on growth and antheridium formation in Anemia phyllitidis].

Planta

Schraudolf H.
PMID: 24549887
Planta. 1967 Jun;74(2):123-47. doi: 10.1007/BF00388325.

A number of inhibitors of DNA-, RNA-, and protein synthesis were applied to prothallia of Anemia phyllitidis, and their effects were investigated with regard to cell division and inhibition of antheridium formation (after induction by gibberellin A3). All compounds...

Fecundity of Panagrellus silusiae Treated with Ethyl methanesulphonate and 5-bromouracil.

Journal of nematology

Samoiloff MR, Smith AC.
PMID: 19322387
J Nematol. 1971 Jul;3(3):299-300.

No abstract available.

Effect of Bromouracil-containing Deoxyribonucleic Acid on Bacillus subtilis.

Journal of bacteriology

Gimlin DM, Hardman SD, Kelley BN, Butler GC, Leach FR.
PMID: 16562122
J Bacteriol. 1966 Aug;92(2):366-74. doi: 10.1128/jb.92.2.366-374.1966.

Gimlin, Dixie M. (Oklahoma State University, Stillwater), Sue D. Hardman, Betty N. Kelley, Grace C. Butler, and Franklin R. Leach. Effect of bromouracil-containing deoxyribonucleic acid on Bacillus subtilis. J. Bacteriol. 92:366-374. 1966.-Replacement of one-half of the thymine with bromouracil...

Reactions of 2-Propanol Radical with Halogenated Organics in Aqueous Solution: Theoretical Evidence for Proton-Coupled Electron Transfer and Competing Mechanisms.

The journal of physical chemistry. B

Ljubić I, Sabljić A, Bonifačić M.
PMID: 27766877
J Phys Chem B. 2016 Nov 17;120(45):11810-11820. doi: 10.1021/acs.jpcb.6b08765. Epub 2016 Nov 02.

The reactions of α-hydroxyalkyl radicals in aqueous medium are of interest because they exhibit a rich variety of fundamentally important competing mechanisms, such as proton-coupled electron transfer (PCET), hydrogen atom transfer, free radical substitutions, abstractions and additions, etc. We...

Microfluorimetric analysis of spatial and temporal patterns of immobilized cell growth.

Biotechnology and bioengineering

Kuhn RH, Peretti SW, Ollis DF.
PMID: 18600770
Biotechnol Bioeng. 1991 Aug 05;38(4):340-52. doi: 10.1002/bit.260380404.

Pronounced spatial nonuniformities in cell density, physiology, and activity frequently arise within densely packed immobilized cell supports. For a more fundamental understanding of immobilized cell phenomena, we have developed high-resolution microfluorimetric procedures to analyze local variations in both immobilized...

DNA synthesis in cytokinin-autotrophic tobacco cells : Effect of bromodeoxyuridine, fluorodeoxyuridine, and kinetin.

Planta

Bezděk M, Vyskot B.
PMID: 24302418
Planta. 1981 Jul;152(3):215-24. doi: 10.1007/BF00385147.

DNA isolated from various Nicotiana tabacum cell types, differing in their degree of hormone autotrophy and incubated in the presence of bromodeoxyuridine (BrdUrd), was analyzed by isopycnic CsCl gradient centrifugation. All cell types incorporate BrdUrd into DNA in such...

INDUCTION OF SPECIFIC MUTATIONS WITH 5-BROMOURACIL.

Proceedings of the National Academy of Sciences of the United States of America

Benzer S, Freese E.
PMID: 16590151
Proc Natl Acad Sci U S A. 1958 Feb;44(2):112-9. doi: 10.1073/pnas.44.2.112.

No abstract available.

Showing 1 to 12 of 19 entries