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Attenuation of the Hypoxia Inducible Factor Pathway after Oncolytic Adenovirus Infection Coincides with Decreased Vessel Perfusion.

Cancers

Yousaf I, Kaeppler J, Frost S, Seymour LW, Jacobus EJ.
PMID: 32244697
Cancers (Basel). 2020 Apr 01;12(4). doi: 10.3390/cancers12040851.

The interplay between oncolytic virus infection and tumour hypoxia is particularly unexplored in vivo, although hypoxia is present in virtually all solid carcinomas. In this study, oncolytic adenovirus infection foci were found within pimonidazole-reactive, oxygen-poor areas in a colorectal...

Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference.

Cancer gene therapy

Dyer A, Baugh R, Chia SL, Frost S, Iris, Jacobus EJ, Khalique H, Pokrovska TD, Scott EM, Taverner WK, Seymour LW, Lei J.
PMID: 30177818
Cancer Gene Ther. 2019 Mar;26(3):59-73. doi: 10.1038/s41417-018-0042-1. Epub 2018 Sep 04.

The 11th International Oncolytic Virus Conference (IOVC) was held from April 9-12, 2018 in Oxford, UK. This is part of the high-profile academic-led series of meetings that was started back in 2002 by Steve Russell and John Bell, with...

Showing 1 to 2 of 2 entries