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Dimethyl fumarate treatment of relapsing-remitting multiple sclerosis influences B-cell subsets.

Neurology(R) neuroimmunology & neuroinflammation

Lundy SK, Wu Q, Wang Q, Dowling CA, Taitano SH, Mao G, Mao-Draayer Y.
PMID: 27006972
Neurol Neuroimmunol Neuroinflamm. 2016 Mar 03;3(2):e211. doi: 10.1212/NXI.0000000000000211. eCollection 2016 Apr.

OBJECTIVE: To test the hypothesis that dimethyl fumarate (Tecfidera, BG-12) affects B-cell subsets in patients with relapsing-remitting multiple sclerosis (RRMS).METHODS: Peripheral blood B cells were compared for surface marker expression in patients with RRMS prior to initiation of treatment,...

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Lundy SK, Wu Q, Wang Q, et al. Dimethyl fumarate treatment of relapsing-remitting multiple sclerosis influences B-cell subsets. Neurol Neuroimmunol Neuroinflamm. 2016;3(2):e211doi: 10.1212/NXI.0000000000000211.
Lundy, S. K., Wu, Q., Wang, Q., Dowling, C. A., Taitano, S. H., Mao, G., & Mao-Draayer, Y. (2016). Dimethyl fumarate treatment of relapsing-remitting multiple sclerosis influences B-cell subsets. Neurology(R) neuroimmunology & neuroinflammation, 3(2), e211. https://doi.org/10.1212/NXI.0000000000000211
Lundy, Steven K, et al. "Dimethyl fumarate treatment of relapsing-remitting multiple sclerosis influences B-cell subsets." Neurology(R) neuroimmunology & neuroinflammation vol. 3,2 (2016): e211. doi: https://doi.org/10.1212/NXI.0000000000000211
Lundy SK, Wu Q, Wang Q, Dowling CA, Taitano SH, Mao G, Mao-Draayer Y. Dimethyl fumarate treatment of relapsing-remitting multiple sclerosis influences B-cell subsets. Neurol Neuroimmunol Neuroinflamm. 2016 Mar 03;3(2):e211. doi: 10.1212/NXI.0000000000000211. eCollection 2016 Apr. PMID: 27006972; PMCID: PMC4784801.
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Activation of Langerhans-Type Dendritic Cells Alters Human Cytomegalovirus Infection and Reactivation in a Stimulus-Dependent Manner.

Frontiers in microbiology

Coronel R, Jesus DM, Dalle Ore L, Mymryk JS, Hertel L.
PMID: 27683575
Front Microbiol. 2016 Sep 14;7:1445. doi: 10.3389/fmicb.2016.01445. eCollection 2016.

Oral mucosal Langerhans cells (LC) are likely to play important roles in host defense against infection by human cytomegalovirus (CMV). We previously showed that in vitro-differentiated immature LC (iLC) populations contain smaller amounts of infected cells but produce higher...

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Coronel R, Jesus DM, Dalle Ore L, et al. Activation of Langerhans-Type Dendritic Cells Alters Human Cytomegalovirus Infection and Reactivation in a Stimulus-Dependent Manner. Front Microbiol. 2016;7:1445doi: 10.3389/fmicb.2016.01445.
Coronel, R., Jesus, D. M., Dalle Ore, L., Mymryk, J. S., & Hertel, L. (2016). Activation of Langerhans-Type Dendritic Cells Alters Human Cytomegalovirus Infection and Reactivation in a Stimulus-Dependent Manner. Frontiers in microbiology, 71445. https://doi.org/10.3389/fmicb.2016.01445
Coronel, Roxanne, et al. "Activation of Langerhans-Type Dendritic Cells Alters Human Cytomegalovirus Infection and Reactivation in a Stimulus-Dependent Manner." Frontiers in microbiology vol. 7 (2016): 1445. doi: https://doi.org/10.3389/fmicb.2016.01445
Coronel R, Jesus DM, Dalle Ore L, Mymryk JS, Hertel L. Activation of Langerhans-Type Dendritic Cells Alters Human Cytomegalovirus Infection and Reactivation in a Stimulus-Dependent Manner. Front Microbiol. 2016 Sep 14;7:1445. doi: 10.3389/fmicb.2016.01445. eCollection 2016. PMID: 27683575; PMCID: PMC5021960.
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Expression of Human Soluble CD40 Ligand in Pichia pastoris and Its Effects on Dendritic Cells and Malignant B Cells.

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

Shi HZ, Huang WD, Wang YD, Lu Y, Jiang Y, Zhang XG.
PMID: 12058165
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2000;32(6):562-568.

CD40 ligand (CD40L) is a member of the tumor necrosis factor (TNF) superfamily and is expressed primarily on the activated CD4( )T lymphocytes. The CD40 molecule, the cognate receptor of CD40L presents on many immunocytes such as B lymphocytes,...

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Shi HZ, Huang WD, Wang YD, et al. Expression of Human Soluble CD40 Ligand in Pichia pastoris and Its Effects on Dendritic Cells and Malignant B Cells. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2000;32(6):562-568
Shi, H. Z., Huang, W. D., Wang, Y. D., Lu, Y., Jiang, Y., & Zhang, X. G. (2000). Expression of Human Soluble CD40 Ligand in Pichia pastoris and Its Effects on Dendritic Cells and Malignant B Cells. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica, 32(6), 562-568.
Shi, Hong-Zhen, et al. "Expression of Human Soluble CD40 Ligand in Pichia pastoris and Its Effects on Dendritic Cells and Malignant B Cells." Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica vol. 32,6 (2000): 562-568.
Shi HZ, Huang WD, Wang YD, Lu Y, Jiang Y, Zhang XG. Expression of Human Soluble CD40 Ligand in Pichia pastoris and Its Effects on Dendritic Cells and Malignant B Cells. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2000;32(6):562-568. PMID: 12058165.
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Immunomodulation for the prevention and treatment of lung infections.

Seminars in respiratory and critical care medicine

Standiford TJ, Deng JC.
PMID: 16088453
Semin Respir Crit Care Med. 2004 Feb;25(1):95-108. doi: 10.1055/s-2004-822309.

The clearance of microbes from the respiratory tract requires the generation of a vigorous and compartmentalized host immune response. When pulmonary infection occurs in the setting of impaired innate and acquired immune responses, antimicrobial agents alone often cannot cure...

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Standiford TJ, Deng JC. Immunomodulation for the prevention and treatment of lung infections. Semin Respir Crit Care Med. 2004;25(1):95-108doi: 10.1055/s-2004-822309.
Standiford, T. J., & Deng, J. C. (2004). Immunomodulation for the prevention and treatment of lung infections. Seminars in respiratory and critical care medicine, 25(1), 95-108. https://doi.org/10.1055/s-2004-822309
Standiford, Theodore J, and Deng, Jane C. "Immunomodulation for the prevention and treatment of lung infections." Seminars in respiratory and critical care medicine vol. 25,1 (2004): 95-108. doi: https://doi.org/10.1055/s-2004-822309
Standiford TJ, Deng JC. Immunomodulation for the prevention and treatment of lung infections. Semin Respir Crit Care Med. 2004 Feb;25(1):95-108. doi: 10.1055/s-2004-822309. PMID: 16088453.
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SOLUBLE CD40 LIGAND IN DEMENTIA.

Drugs of the future

Giunta B, Figueroa KP, Town T, Tan J.
PMID: 19777117
Drugs Future. 2009 Apr 01;34(4):333-340. doi: 10.1358/dof.2009.034.04.1358595.

Some 15-20% of the population over the age of 65 years suffer from dementia, currently one of the leading causes of death behind cardiovascular diseases, cancer and cerebrovascular diseases. The major forms of dementia share in common overactivation of...

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Giunta B, Figueroa KP, Town T, et al. SOLUBLE CD40 LIGAND IN DEMENTIA. Drugs Future. 2009;34(4):333-340doi: 10.1358/dof.2009.034.04.1358595.
Giunta, B., Figueroa, K. P., Town, T., & Tan, J. (2009). SOLUBLE CD40 LIGAND IN DEMENTIA. Drugs of the future, 34(4), 333-340. https://doi.org/10.1358/dof.2009.034.04.1358595
Giunta, B, et al. "SOLUBLE CD40 LIGAND IN DEMENTIA." Drugs of the future vol. 34,4 (2009): 333-340. doi: https://doi.org/10.1358/dof.2009.034.04.1358595
Giunta B, Figueroa KP, Town T, Tan J. SOLUBLE CD40 LIGAND IN DEMENTIA. Drugs Future. 2009 Apr 01;34(4):333-340. doi: 10.1358/dof.2009.034.04.1358595. PMID: 19777117; PMCID: PMC2748392.
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The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects.

PPAR research

Spinelli SL, O'Brien JJ, Bancos S, Lehmann GM, Springer DL, Blumberg N, Francis CW, Taubman MB, Phipps RP.
PMID: 18288284
PPAR Res. 2008;2008:328172. doi: 10.1155/2008/328172.

Historically, platelets were viewed as simple anucleate cells responsible for initiating thrombosis and maintaining hemostasis, but clearly they are also key mediators of inflammation and immune cell activation. An emerging body of evidence links platelet function and thrombosis to...

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Spinelli SL, O'Brien JJ, Bancos S, et al. The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects. PPAR Res. 2008;2008:328172doi: 10.1155/2008/328172.
Spinelli, S. L., O'Brien, J. J., Bancos, S., Lehmann, G. M., Springer, D. L., Blumberg, N., Francis, C. W., Taubman, M. B., & Phipps, R. P. (2008). The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects. PPAR research, 2008328172. https://doi.org/10.1155/2008/328172
Spinelli, S L, et al. "The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects." PPAR research vol. 2008 (2008): 328172. doi: https://doi.org/10.1155/2008/328172
Spinelli SL, O'Brien JJ, Bancos S, Lehmann GM, Springer DL, Blumberg N, Francis CW, Taubman MB, Phipps RP. The PPAR-Platelet Connection: Modulators of Inflammation and Potential Cardiovascular Effects. PPAR Res. 2008;2008:328172. doi: 10.1155/2008/328172. PMID: 18288284; PMCID: PMC2233896.
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Orally tolerant CD4 T cells respond poorly to antigenic stimulation but strongly to direct stimulation of intracellular signaling pathways.

Cytotechnology

Asai K, Hachimura S, Toraya T, Kaminogawa S.
PMID: 19003325
Cytotechnology. 2001 Jul;36(1):145-53. doi: 10.1023/A:1014009328207.

The response of splenic CD4 T cells from ovalbumin (OVA)-specific T cell receptor (TCR) transgenic mice after long-term feeding of a diet containing this antigen was examined. These CD4 T cells exhibited a decreased response to OVA peptide stimulation,...

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Asai K, Hachimura S, Toraya T, et al. Orally tolerant CD4 T cells respond poorly to antigenic stimulation but strongly to direct stimulation of intracellular signaling pathways. Cytotechnology. 2001;36(1):145-53doi: 10.1023/A:1014009328207.
Asai, K., Hachimura, S., Toraya, T., & Kaminogawa, S. (2001). Orally tolerant CD4 T cells respond poorly to antigenic stimulation but strongly to direct stimulation of intracellular signaling pathways. Cytotechnology, 36(1), 145-53. https://doi.org/10.1023/A:1014009328207
Asai, K, et al. "Orally tolerant CD4 T cells respond poorly to antigenic stimulation but strongly to direct stimulation of intracellular signaling pathways." Cytotechnology vol. 36,1 (2001): 145-53. doi: https://doi.org/10.1023/A:1014009328207
Asai K, Hachimura S, Toraya T, Kaminogawa S. Orally tolerant CD4 T cells respond poorly to antigenic stimulation but strongly to direct stimulation of intracellular signaling pathways. Cytotechnology. 2001 Jul;36(1):145-53. doi: 10.1023/A:1014009328207. PMID: 19003325; PMCID: PMC3449668.
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The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis.

Korean circulation journal

Lee K, Ahn TH, Kang WC, Han SH, Choi IS, Shin EK.
PMID: 22194758
Korean Circ J. 2011 Nov;41(11):641-8. doi: 10.4070/kcj.2011.41.11.641. Epub 2011 Nov 29.

BACKGROUND AND OBJECTIVES: The aim of this study was to compare the effects of a combination of niacin and simvastatin to simvastatin alone, on plaque regression and inflammatory makers.SUBJECTS AND METHODS: The study had a prospective, randomized design. Subjects...

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Lee K, Ahn TH, Kang WC, et al. The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis. Korean Circ J. 2011;41(11):641-8doi: 10.4070/kcj.2011.41.11.641.
Lee, K., Ahn, T. H., Kang, W. C., Han, S. H., Choi, I. S., & Shin, E. K. (2011). The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis. Korean circulation journal, 41(11), 641-8. https://doi.org/10.4070/kcj.2011.41.11.641
Lee, Kyounghoon, et al. "The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis." Korean circulation journal vol. 41,11 (2011): 641-8. doi: https://doi.org/10.4070/kcj.2011.41.11.641
Lee K, Ahn TH, Kang WC, Han SH, Choi IS, Shin EK. The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis. Korean Circ J. 2011 Nov;41(11):641-8. doi: 10.4070/kcj.2011.41.11.641. Epub 2011 Nov 29. PMID: 22194758; PMCID: PMC3242018.
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The Interaction Between Allelic Variants of CD86 and CD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis.

Allergy, asthma & immunology research

Lee SH, Lee EB, Shin ES, Lee JE, Cho SH, Min KU, Park HW.
PMID: 24587950
Allergy Asthma Immunol Res. 2014 Mar;6(2):137-41. doi: 10.4168/aair.2014.6.2.137. Epub 2013 Oct 23.

PURPOSE: Allergic asthma (AA) and rheumatoid arthritis (RA) are immune tolerance-related diseases, and immune tolerance is known to be influenced by costimulatory molecules. In this study, we sought to identify common genetic susceptibility in AA and RA.METHODS: Two hundred...

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Lee SH, Lee EB, Shin ES, et al. The Interaction Between Allelic Variants of CD86 and CD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis. Allergy Asthma Immunol Res. 2013;6(2):137-41doi: 10.4168/aair.2014.6.2.137.
Lee, S. H., Lee, E. B., Shin, E. S., Lee, J. E., Cho, S. H., Min, K. U., & Park, H. W. (2014). The Interaction Between Allelic Variants of CD86 and CD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis. Allergy, asthma & immunology research, 6(2), 137-41. https://doi.org/10.4168/aair.2014.6.2.137
Lee, So-Hee, et al. "The Interaction Between Allelic Variants of CD86 and CD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis." Allergy, asthma & immunology research vol. 6,2 (2014): 137-41. doi: https://doi.org/10.4168/aair.2014.6.2.137
Lee SH, Lee EB, Shin ES, Lee JE, Cho SH, Min KU, Park HW. The Interaction Between Allelic Variants of CD86 and CD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis. Allergy Asthma Immunol Res. 2014 Mar;6(2):137-41. doi: 10.4168/aair.2014.6.2.137. Epub 2013 Oct 23. PMID: 24587950; PMCID: PMC3936042.
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Influence of circadian blood pressure alterations on serum SCUBE-1 and soluble CD40 ligand levels in patients with essential hypertension.

American journal of cardiovascular disease

Guzel M, Dogru MT, Simsek V, Demir V, Alp C, Kandemir H, Yildirim N, Kisa U.
PMID: 31516762
Am J Cardiovasc Dis. 2019 Aug 15;9(4):42-48. eCollection 2019.

BACKGROUND: Dipper and non-dipper hypertension are different clinical forms of essential hypertension. In this study, the effect of circadian blood pressure changes on serum SCUBE-1 and soluble CD40 ligand (sCD40L) levels was investigated in patients with hypertension.METHODS: A total...

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Guzel M, Dogru MT, Simsek V, et al. Influence of circadian blood pressure alterations on serum SCUBE-1 and soluble CD40 ligand levels in patients with essential hypertension. Am J Cardiovasc Dis. 2019;9(4):42-48
Guzel, M., Dogru, M. T., Simsek, V., Demir, V., Alp, C., Kandemir, H., Yildirim, N., & Kisa, U. (2019). Influence of circadian blood pressure alterations on serum SCUBE-1 and soluble CD40 ligand levels in patients with essential hypertension. American journal of cardiovascular disease, 9(4), 42-48.
Guzel, Murat, et al. "Influence of circadian blood pressure alterations on serum SCUBE-1 and soluble CD40 ligand levels in patients with essential hypertension." American journal of cardiovascular disease vol. 9,4 (2019): 42-48.
Guzel M, Dogru MT, Simsek V, Demir V, Alp C, Kandemir H, Yildirim N, Kisa U. Influence of circadian blood pressure alterations on serum SCUBE-1 and soluble CD40 ligand levels in patients with essential hypertension. Am J Cardiovasc Dis. 2019 Aug 15;9(4):42-48. eCollection 2019. PMID: 31516762; PMCID: PMC6737351.
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Soluble CD40 Ligand in Atrial Fibrillation: Time and Other Confounding Factors.

JACC. Clinical electrophysiology

Sanders P, Lim HS.
PMID: 29759584
JACC Clin Electrophysiol. 2016 Oct;2(5):633-635. doi: 10.1016/j.jacep.2016.05.011. Epub 2016 Aug 03.

No abstract available.

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Sanders P, Lim HS. Soluble CD40 Ligand in Atrial Fibrillation: Time and Other Confounding Factors. JACC Clin Electrophysiol. 2016;2(5):633-635doi: 10.1016/j.jacep.2016.05.011.
Sanders, P., & Lim, H. S. (2016). Soluble CD40 Ligand in Atrial Fibrillation: Time and Other Confounding Factors. JACC. Clinical electrophysiology, 2(5), 633-635. https://doi.org/10.1016/j.jacep.2016.05.011
Sanders, Prashanthan, and Lim, Han S. "Soluble CD40 Ligand in Atrial Fibrillation: Time and Other Confounding Factors." JACC. Clinical electrophysiology vol. 2,5 (2016): 633-635. doi: https://doi.org/10.1016/j.jacep.2016.05.011
Sanders P, Lim HS. Soluble CD40 Ligand in Atrial Fibrillation: Time and Other Confounding Factors. JACC Clin Electrophysiol. 2016 Oct;2(5):633-635. doi: 10.1016/j.jacep.2016.05.011. Epub 2016 Aug 03. PMID: 29759584.
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Evaluation of plasma levels of neopterin and soluble CD40 ligand in patients with acute ischemic stroke in upper Egypt: can they surrogate the severity and functional outcome?.

Neuropsychiatric disease and treatment

Tony AA, Tony EA, Mohammed WS, Kholef EF.
PMID: 30863079
Neuropsychiatr Dis Treat. 2019 Feb 22;15:575-586. doi: 10.2147/NDT.S177726. eCollection 2019.

BACKGROUND: Inflammation constitutes a major component of ischemic stroke pathology. The prognostic value of "neopterin" and soluble CD40 ligand (sCD40L), as a potential biomarker of ischemic stroke, has been less extensively studied.OBJECTIVES OF THE STUDY: This study aims at...

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Tony AA, Tony EA, Mohammed WS, et al. Evaluation of plasma levels of neopterin and soluble CD40 ligand in patients with acute ischemic stroke in upper Egypt: can they surrogate the severity and functional outcome?. Neuropsychiatr Dis Treat. 2019;15:575-586doi: 10.2147/NDT.S177726.
Tony, A. A., Tony, E. A., Mohammed, W. S., & Kholef, E. F. (2019). Evaluation of plasma levels of neopterin and soluble CD40 ligand in patients with acute ischemic stroke in upper Egypt: can they surrogate the severity and functional outcome?. Neuropsychiatric disease and treatment, 15575-586. https://doi.org/10.2147/NDT.S177726
Tony, Abeer A, et al. "Evaluation of plasma levels of neopterin and soluble CD40 ligand in patients with acute ischemic stroke in upper Egypt: can they surrogate the severity and functional outcome?." Neuropsychiatric disease and treatment vol. 15 (2019): 575-586. doi: https://doi.org/10.2147/NDT.S177726
Tony AA, Tony EA, Mohammed WS, Kholef EF. Evaluation of plasma levels of neopterin and soluble CD40 ligand in patients with acute ischemic stroke in upper Egypt: can they surrogate the severity and functional outcome?. Neuropsychiatr Dis Treat. 2019 Feb 22;15:575-586. doi: 10.2147/NDT.S177726. eCollection 2019. PMID: 30863079; PMCID: PMC6390873.
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Showing 1 to 12 of 172 entries