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Showing 1 to 7 of 7 entries
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A role for the orphan nuclear receptor TLX in the interaction between neural precursor cells and microglia.

Neuronal signaling

Kozareva DA, Moloney GM, Hoban AE, Rossini V, Nally K, Cryan JF, Nolan YM.
PMID: 32269832
Neuronal Signal. 2019 Mar;3(1):NS20180177. doi: 10.1042/NS20180177. Epub 2019 Feb 22.

Microglia are an essential component of the neurogenic niche in the adult hippocampus and are involved in the control of neural precursor cell (NPC) proliferation, differentiation and the survival and integration of newborn neurons in hippocampal circuitry. Microglial and...

CX3C-chemokine receptor 1 modulates cognitive dysfunction induced by sleep deprivation.

Chinese medical journal

Xin J, Wang C, Cheng X, Xie C, Zhang Q, Ke Y, Huang X, Chen X, Pan X.
PMID: 34732662
Chin Med J (Engl). 2021 Nov 03;135(2):205-215. doi: 10.1097/CM9.0000000000001769.

BACKGROUND: Microglia plays an indispensable role in the pathological process of sleep deprivation (SD). Here, the potential role of microglial CX3C-chemokine receptor 1 (CX3CR1) in modulating the cognition decline during SD was evaluated in terms of microglial neuroinflammation and...

CX3C-chemokine receptor 1 modulates cognitive dysfunction induced by sleep deprivation.

Chinese medical journal

Xin J, Wang C, Cheng X, Xie C, Zhang Q, Ke Y, Huang X, Chen X, Pan X.
PMID: 34732662
Chin Med J (Engl). 2021 Nov 03;135(2):205-215. doi: 10.1097/CM9.0000000000001769.

BACKGROUND: Microglia plays an indispensable role in the pathological process of sleep deprivation (SD). Here, the potential role of microglial CX3C-chemokine receptor 1 (CX3CR1) in modulating the cognition decline during SD was evaluated in terms of microglial neuroinflammation and...

CX3C-chemokine receptor 1 modulates cognitive dysfunction induced by sleep deprivation.

Chinese medical journal

Xin JW, Wang C, Cheng XJ, Xie CF, Zhang QY, Ke YL, Huang XY, Chen XC, Pan XD.
PMID: 34732662
Chin Med J (Engl). 2021 Nov 03; doi: 10.1097/CM9.0000000000001769. Epub 2021 Nov 03.

BACKGROUND: Microglia plays an indispensable role in the pathological process of sleep deprivation (SD). Here, the potential role of microglial CX3C-chemokine receptor 1 (CX3CR1) in modulating the cognition decline during SD was evaluated in terms of microglial neuroinflammation and...

The involvement of microglial CX3CR1 in heat acclimation-induced amelioration of adult hippocampal neurogenesis impairment in EMF-exposed mice.

Brain research bulletin

He GL, Wang ZZ, Yu XT, Shen TT, Luo Z, Li P, Luo X, Tan YL, Gao P, Yang XS.
PMID: 34555433
Brain Res Bull. 2021 Dec;177:181-193. doi: 10.1016/j.brainresbull.2021.09.018. Epub 2021 Sep 21.

Microglial CX3C chemokine receptor 1 (CX3CR1) has been implicated in numerous cellular mechanisms, including signalling pathways that regulate brain homoeostasis and adult hippocampal neurogenesis. Specific environmental conditions can impair hippocampal neurogenesis-related cognition, learning and memory. However, the role of...

Treatment with an Anti-CX3CL1 Antibody Suppresses M1 Macrophage Infiltration in Interstitial Lung Disease in SKG Mice.

Pharmaceuticals (Basel, Switzerland)

Mizutani S, Nishio J, Kondo K, Motomura K, Yamada Z, Masuoka S, Yamada S, Muraoka S, Ishii N, Kuboi Y, Sendo S, Mikami T, Imai T, Nanki T.
PMID: 34067842
Pharmaceuticals (Basel). 2021 May 17;14(5). doi: 10.3390/ph14050474.

CX3C Motif Chemokine Ligand 1 (CX3CL1; fractalkine) has been implicated in the pathogenesis of rheumatoid arthritis (RA) and its inhibition was found to attenuate arthritis in mice as well as in a clinical trial. Therefore, we investigated the effects...

Shedding light on the role of CX3CR1 in the pathogenesis of schizophrenia.

Pharmacological reports : PR

Chamera K, Szuster-Głuszczak M, Basta-Kaim A.
PMID: 34021899
Pharmacol Rep. 2021 Aug;73(4):1063-1078. doi: 10.1007/s43440-021-00269-5. Epub 2021 May 22.

Schizophrenia has a complex and heterogeneous molecular and clinical picture. Over the years of research on this disease, many factors have been suggested to contribute to its pathogenesis. Recently, the inflammatory processes have gained particular interest in the context...

Showing 1 to 7 of 7 entries