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Showing 1 to 12 of 1383 entries
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Predictors of spine deformity progression in adolescent idiopathic scoliosis: A systematic review with meta-analysis.

World journal of orthopedics

Noshchenko A, Hoffecker L, Lindley EM, Burger EL, Cain CM, Patel VV, Bradford AP.
PMID: 26301183
World J Orthop. 2015 Aug 18;6(7):537-58. doi: 10.5312/wjo.v6.i7.537. eCollection 2015 Aug 18.

SELECTION CRITERIA: (1) study design: randomized controlled clinical trials, prospective cohort studies and case series, retrospective comparative and none comparative studies; (2) participants: adolescents with AIS aged from 10 to 20 years; and (3) treatment: observation, bracing, and other.SEARCH...

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

Agrawal R, Kalmady SV, Venkatasubramanian G.
PMID: 28449558
Clin Psychopharmacol Neurosci. 2017 May 31;15(2):115-125. doi: 10.9758/cpn.2017.15.2.115.

OBJECTIVE: Deficient brain-derived neurotrophic factor (BDNF) is one of the important mechanisms underlying the neuroplasticity abnormalities in schizophrenia. Aberration in BDNF signaling pathways directly or circuitously influences neurotransmitters like glutamate and gamma-aminobutyric acid (GABA). For the first time, this...

Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells.

Hepatology research : the official journal of the Japan Society of Hepatology

Goto F, Kakinuma S, Miyoshi M, Tsunoda T, Kaneko S, Sato A, Asano Y, Otani S, Azuma S, Nagata H, Kawai-Kitahata F, Murakawa M, Nitta S, Itsui Y, Nakagawa M, Asahina Y, Watanabe M.
PMID: 27670640
Hepatol Res. 2017 Aug;47(9):941-952. doi: 10.1111/hepr.12823. Epub 2016 Oct 31.

Fetal hepatic stem/progenitor cells, called hepatoblasts, play central roles in liver organogenesis; however, molecular mechanisms regulating proliferation and terminal differentiation of such cells have not been completely elucidated. Bone morphogenetic protein-4 (BMP-4) is essential for the development of stem...

CASK and CaMKII function in Drosophila memory.

Frontiers in neuroscience

Malik BR, Hodge JJ.
PMID: 25009461
Front Neurosci. 2014 Jun 25;8:178. doi: 10.3389/fnins.2014.00178. eCollection 2014.

Calcium (Ca(2+)) and Calmodulin (CaM)-dependent serine/threonine kinase II (CaMKII) plays a central role in synaptic plasticity and memory due to its ability to phosphorylate itself and regulate its own kinase activity. Autophosphorylation at threonine 287 (T287) switches CaMKII to...

Aspergillus fumigatus-Related Species in Clinical Practice.

Frontiers in microbiology

Lamoth F.
PMID: 27242710
Front Microbiol. 2016 May 17;7:683. doi: 10.3389/fmicb.2016.00683. eCollection 2016.

Aspergillus fumigatus is the main etiologic agent of invasive aspergillosis (IA). Other Aspergillus species belonging to the section Fumigati (A. fumigatus complex) may occasionally be the cause of IA. These strains are often misidentified, as they cannot be distinguished...

2D FT-ICR MS of Calmodulin: A Top-Down and Bottom-Up Approach.

Journal of the American Society for Mass Spectrometry

Floris F, van Agthoven M, Chiron L, Soulby AJ, Wootton CA, Lam YP, Barrow MP, Delsuc MA, O'Connor PB.
PMID: 27431513
J Am Soc Mass Spectrom. 2016 Sep;27(9):1531-8. doi: 10.1007/s13361-016-1431-z. Epub 2016 Jul 18.

Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FT-ICR MS) allows data-independent fragmentation of all ions in a sample and correlation of fragment ions to their precursors through the modulation of precursor ion cyclotron radii prior to fragmentation....

Inference of Calmodulin's Ca.

Journal of chemical theory and computation

Westerlund AM, Harpole TJ, Blau C, Delemotte L.
PMID: 29144736
J Chem Theory Comput. 2018 Jan 09;14(1):63-71. doi: 10.1021/acs.jctc.7b00346. Epub 2017 Dec 06.

A free energy landscape estimation method based on the well-known Gaussian mixture model (GMM) is used to compare the efficiencies of thermally enhanced sampling methods with respect to regular molecular dynamics. The simulations are carried out on two binding...

Ca(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequences.

Frontiers in pharmacology

Bers DM, Morotti S.
PMID: 24987371
Front Pharmacol. 2014 Jun 17;5:144. doi: 10.3389/fphar.2014.00144. eCollection 2014.

The cardiac voltage gated Ca(2+) current (ICa) is critical to the electrophysiological properties, excitation-contraction coupling, mitochondrial energetics, and transcriptional regulation in heart. Thus, it is not surprising that cardiac ICa is regulated by numerous pathways. This review will focus...

Mapping the sevoflurane-binding sites of calmodulin.

Pharmacology research & perspectives

Brath U, Lau K, Van Petegem F, Erdélyi M.
PMID: 25505574
Pharmacol Res Perspect. 2014 Feb;2(1):5. doi: 10.1002/prp2.25. Epub 2014 Feb 12.

General anesthetics, with sevoflurane (SF) being the first choice inhalational anesthetic agent, provide reversible, broad depressor effects on the nervous system yet have a narrow margin of safety. As characterization of low-affinity binding interactions of volatile substances is exceptionally...

Region-Specific Disruption of Adenylate Cyclase Type 1 Gene Differentially Affects Somatosensorimotor Behaviors in Mice(1,2,3).

eNeuro

Arakawa H, Akkentli F, Erzurumlu RS.
PMID: 26464960
eNeuro. 2014 Nov 12;1(1). doi: 10.1523/ENEURO.0007-14.2014. eCollection 2014.

Cover FigureRegion-specific adenylyl cyclase 1 (AC1) loss of function differentially affects both patterning and sensorimotor behaviors in mice. AC1 is expressed at all levels of the somatosensory pathway and plays a major role in refinement and patterning of topographic...

PKA and cAMP/CNG Channels Independently Regulate the Cholinergic Ca(2+)-Response of Drosophila Mushroom Body Neurons.

eNeuro

Pavot P, Carbognin E, Martin JR.
PMID: 26464971
eNeuro. 2015 Apr 30;2(2). doi: 10.1523/ENEURO.0054-14.2015. eCollection 2015.

The mushroom bodies (MBs), one of the main structures in the adult insect brain, play a critical role in olfactory learning and memory. Though historical genes such as dunce and rutabaga, which regulate the level of cAMP, were identified...

Characterisation of the Egeria densa Planch. leaf symplast : Inhibition of the intercellular movement of fluorescent probes by group II ions.

Planta

Erwee MG, Goodwin PB.
PMID: 24264752
Planta. 1983 Aug;158(4):320-8. doi: 10.1007/BF00397334.

The hydrophyllic dyes fluorescein glutamic acid, fluorescein glutamylglutamic acid (F(Glu)2), fluorescein hexaglycine, fluorescein leucyldiglutamyl-leucine and 6-carboxyfluorescein are unable to pass the plasmalemma in leaves of E. densa. However, when injected into single cells the dye conjugates of molecular weight...

Showing 1 to 12 of 1383 entries