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Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy.

International journal of clinical and experimental medicine

Sefil F, Arık AE, Acar MD, Bostancı MÖ, Bagirici F, Kozan R.
PMID: 26379841
Int J Clin Exp Med. 2015 Jul 15;8(7):10508-14. eCollection 2015.

Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization. Therefore, the aim of the present study is to explore the combination valproic acid with carbenoxolone...

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Sefil F, Arık AE, Acar MD, et al. Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy. Int J Clin Exp Med. 2015;8(7):10508-14
Sefil, F., Arık, A. E., Acar, M. D., Bostancı, M. �. �., Bagirici, F., & Kozan, R. (2015). Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy. International journal of clinical and experimental medicine, 8(7), 10508-14.
Sefil, Fatih, et al. "Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy." International journal of clinical and experimental medicine vol. 8,7 (2015): 10508-14.
Sefil F, Arık AE, Acar MD, Bostancı MÖ, Bagirici F, Kozan R. Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy. Int J Clin Exp Med. 2015 Jul 15;8(7):10508-14. eCollection 2015. PMID: 26379841; PMCID: PMC4565224.
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Specificity of the mineralocorticoid receptor: crucial role of 11beta-hydroxysteroid dehydrogenase.

Trends in endocrinology and metabolism: TEM

Steward PM, Edwards CR.
PMID: 18411122
Trends Endocrinol Metab. 1990 Mar-Apr;1(4):225-30. doi: 10.1016/1043-2760(90)90057-a.

Research on the enzyme 11beta-hydroxysteroid dehydrogenase, initially performed on congenital deficiency of the enzyme, and later work on deficiency of the enzyme after licorice and carbenoxolone administration, led to the hypothesis that 11beta-hydroxysteroid dehydrogenase conferred specificity on the mineralocorticoid...

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Steward PM, Edwards CR. Specificity of the mineralocorticoid receptor: crucial role of 11beta-hydroxysteroid dehydrogenase. Trends Endocrinol Metab. 1990;1(4):225-30doi: 10.1016/1043-2760(90)90057-a.
Steward, P. M., & Edwards, C. R. (1990). Specificity of the mineralocorticoid receptor: crucial role of 11beta-hydroxysteroid dehydrogenase. Trends in endocrinology and metabolism: TEM, 1(4), 225-30. https://doi.org/10.1016/1043-2760(90)90057-a
Steward, P M, and Edwards, C R. "Specificity of the mineralocorticoid receptor: crucial role of 11beta-hydroxysteroid dehydrogenase." Trends in endocrinology and metabolism: TEM vol. 1,4 (1990): 225-30. doi: https://doi.org/10.1016/1043-2760(90)90057-a
Steward PM, Edwards CR. Specificity of the mineralocorticoid receptor: crucial role of 11beta-hydroxysteroid dehydrogenase. Trends Endocrinol Metab. 1990 Mar-Apr;1(4):225-30. doi: 10.1016/1043-2760(90)90057-a. PMID: 18411122.
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Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors.

Frontiers in pharmacology

Svobodova I, Bhattaracharya A, Ivetic M, Bendova Z, Zemkova H.
PMID: 29559915
Front Pharmacol. 2018 Mar 06;9:192. doi: 10.3389/fphar.2018.00192. eCollection 2018.

The circadian rhythms in physiological and behavioral functions are driven by a pacemaker located in the suprachiasmatic nucleus (SCN). The rhythms continue in constant darkness and depend on cell-cell communication between neurons and glia. The SCN astrocytes generate also...

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Svobodova I, Bhattaracharya A, Ivetic M, et al. Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors. Front Pharmacol. 2018;9:192doi: 10.3389/fphar.2018.00192.
Svobodova, I., Bhattaracharya, A., Ivetic, M., Bendova, Z., & Zemkova, H. (2018). Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors. Frontiers in pharmacology, 9192. https://doi.org/10.3389/fphar.2018.00192
Svobodova, Irena, et al. "Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors." Frontiers in pharmacology vol. 9 (2018): 192. doi: https://doi.org/10.3389/fphar.2018.00192
Svobodova I, Bhattaracharya A, Ivetic M, Bendova Z, Zemkova H. Circadian ATP Release in Organotypic Cultures of the Rat Suprachiasmatic Nucleus Is Dependent on P2X7 and P2Y Receptors. Front Pharmacol. 2018 Mar 06;9:192. doi: 10.3389/fphar.2018.00192. eCollection 2018. PMID: 29559915; PMCID: PMC5845546.
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Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells.

Cancers

Freeman TJ, Sayedyahossein S, Johnston D, Sanchez-Pupo RE, O'Donnell B, Huang K, Lakhani Z, Nouri-Nejad D, Barr KJ, Harland L, Latosinsky S, Grant A, Dagnino L, Penuela S.
PMID: 30654593
Cancers (Basel). 2019 Jan 16;11(1). doi: 10.3390/cancers11010102.

Pannexin 1 (PANX1) is a channel-forming glycoprotein expressed in many tissues including the skin. PANX1 channels allow the passage of ions and molecules up to 1 kDa, including ATP and other metabolites. In this study, we show that PANX1...

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Freeman TJ, Sayedyahossein S, Johnston D, et al. Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells. Cancers (Basel). 2019;11(1)doi: 10.3390/cancers11010102.
Freeman, T. J., Sayedyahossein, S., Johnston, D., Sanchez-Pupo, R. E., O'Donnell, B., Huang, K., Lakhani, Z., Nouri-Nejad, D., Barr, K. J., Harland, L., Latosinsky, S., Grant, A., Dagnino, L., & Penuela, S. (2019). Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells. Cancers, 11(1), . https://doi.org/10.3390/cancers11010102
Freeman, Taylor J, et al. "Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells." Cancers vol. 11,1 (2019). doi: https://doi.org/10.3390/cancers11010102
Freeman TJ, Sayedyahossein S, Johnston D, Sanchez-Pupo RE, O'Donnell B, Huang K, Lakhani Z, Nouri-Nejad D, Barr KJ, Harland L, Latosinsky S, Grant A, Dagnino L, Penuela S. Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells. Cancers (Basel). 2019 Jan 16;11(1). doi: 10.3390/cancers11010102. PMID: 30654593; PMCID: PMC6356688.
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Action of mefloquine/amitriptyline THN101 combination on neuropathic mechanical hypersensitivity in mice.

Pain

Letellier B, Kremer M, Becker LJ, Andry V, Goumon Y, Leboulleux Q, Hener P, Inquimbert P, Couqueberg N, Waltisperger E, Yalcin I, Mouthon F, Droguerre M, Charvériat M, Barrot M.
PMID: 33769363
Pain. 2021 Dec 01;162(12):2841-2853. doi: 10.1097/j.pain.0000000000002276.

ABSTRACT: Tricyclic antidepressants that inhibit serotonin and noradrenaline reuptake, such as amitriptyline, are among the first-line treatments for neuropathic pain, which is caused by a lesion or disease affecting the somatosensory nervous system. These treatments are, however, partially efficient...

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Letellier B, Kremer M, Becker LJ, et al. Action of mefloquine/amitriptyline THN101 combination on neuropathic mechanical hypersensitivity in mice. Pain. 2021;162(12):2841-2853doi: 10.1097/j.pain.0000000000002276.
Letellier, B., Kremer, M., Becker, L. J., Andry, V., Goumon, Y., Leboulleux, Q., Hener, P., Inquimbert, P., Couqueberg, N., Waltisperger, E., Yalcin, I., Mouthon, F., Droguerre, M., Charvériat, M., & Barrot, M. (2021). Action of mefloquine/amitriptyline THN101 combination on neuropathic mechanical hypersensitivity in mice. Pain, 162(12), 2841-2853. https://doi.org/10.1097/j.pain.0000000000002276
Letellier, Baptiste, et al. "Action of mefloquine/amitriptyline THN101 combination on neuropathic mechanical hypersensitivity in mice." Pain vol. 162,12 (2021): 2841-2853. doi: https://doi.org/10.1097/j.pain.0000000000002276
Letellier B, Kremer M, Becker LJ, Andry V, Goumon Y, Leboulleux Q, Hener P, Inquimbert P, Couqueberg N, Waltisperger E, Yalcin I, Mouthon F, Droguerre M, Charvériat M, Barrot M. Action of mefloquine/amitriptyline THN101 combination on neuropathic mechanical hypersensitivity in mice. Pain. 2021 Dec 01;162(12):2841-2853. doi: 10.1097/j.pain.0000000000002276. PMID: 33769363; PMCID: PMC8600545.
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Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats.

Biological & pharmaceutical bulletin

Mori A, Namekawa R, Sakamoto K, Ishii K, Nakahara T.
PMID: 34853268
Biol Pharm Bull. 2021;44(12):1860-1865. doi: 10.1248/bpb.b21-00547.

An electrical communication between the endothelial and smooth muscle cells via gap junctions, which provides the signaling pathway known as endothelium-dependent hyperpolarization (EDH), plays a crucial role in controlling the vascular tone. In this study, we investigated the role...

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Mori A, Namekawa R, Sakamoto K, et al. Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats. Biol Pharm Bull. 2021;44(12):1860-1865doi: 10.1248/bpb.b21-00547.
Mori, A., Namekawa, R., Sakamoto, K., Ishii, K., & Nakahara, T. (2021). Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats. Biological & pharmaceutical bulletin, 44(12), 1860-1865. https://doi.org/10.1248/bpb.b21-00547
Mori, Asami, et al. "Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats." Biological & pharmaceutical bulletin vol. 44,12 (2021): 1860-1865. doi: https://doi.org/10.1248/bpb.b21-00547
Mori A, Namekawa R, Sakamoto K, Ishii K, Nakahara T. Involvement of Gap Junctions in Acetylcholine-Induced Endothelium-Derived Hyperpolarization-Type Dilation of Retinal Arterioles in Rats. Biol Pharm Bull. 2021;44(12):1860-1865. doi: 10.1248/bpb.b21-00547. PMID: 34853268.
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Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter.

European journal of pharmacology

Otsuka Y, Bai X, Tanaka Y, Ihara E, Chinen T, Ogino H, Ogawa Y.
PMID: 34506779
Eur J Pharmacol. 2021 Nov 05;910:174491. doi: 10.1016/j.ejphar.2021.174491. Epub 2021 Sep 09.

The interstitial cells of Cajal (ICCs) play an important role in coordinated gastrointestinal motility. The present study aimed to elucidate whether or how ICCs are involved in the lower esophageal sphincter (LES) relaxation induced by stimulation of the nicotinic...

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Otsuka Y, Bai X, Tanaka Y, et al. Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter. Eur J Pharmacol. 2021;910:174491doi: 10.1016/j.ejphar.2021.174491.
Otsuka, Y., Bai, X., Tanaka, Y., Ihara, E., Chinen, T., Ogino, H., & Ogawa, Y. (2021). Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter. European journal of pharmacology, 910174491. https://doi.org/10.1016/j.ejphar.2021.174491
Otsuka, Yoshihiro, et al. "Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter." European journal of pharmacology vol. 910 (2021): 174491. doi: https://doi.org/10.1016/j.ejphar.2021.174491
Otsuka Y, Bai X, Tanaka Y, Ihara E, Chinen T, Ogino H, Ogawa Y. Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter. Eur J Pharmacol. 2021 Nov 05;910:174491. doi: 10.1016/j.ejphar.2021.174491. Epub 2021 Sep 09. PMID: 34506779.
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Herbal Compatibility of Ginseng and Rhubarb Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Injury of Rats.

Frontiers in physiology

Yang WT, Wang Y, Shi YH, Fu H, Xu Z, Xu QQ, Zheng GQ.
PMID: 31572219
Front Physiol. 2019 Sep 13;10:1174. doi: 10.3389/fphys.2019.01174. eCollection 2019.

OBJECTIVE: Ischemic stroke is a complex multifactorial disease caused by interactions among polygenetic, environmental, and lifestyle factors with limited effective treatments. Multi-herbal formulae have long been used for stroke through herbal compatibility in traditional Chinese medicine (TCM); however, there...

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Yang WT, Wang Y, Shi YH, et al. Herbal Compatibility of Ginseng and Rhubarb Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Injury of Rats. Front Physiol. 2019;10:1174doi: 10.3389/fphys.2019.01174.
Yang, W. T., Wang, Y., Shi, Y. H., Fu, H., Xu, Z., Xu, Q. Q., & Zheng, G. Q. (2019). Herbal Compatibility of Ginseng and Rhubarb Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Injury of Rats. Frontiers in physiology, 101174. https://doi.org/10.3389/fphys.2019.01174
Yang, Wen-Ting, et al. "Herbal Compatibility of Ginseng and Rhubarb Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Injury of Rats." Frontiers in physiology vol. 10 (2019): 1174. doi: https://doi.org/10.3389/fphys.2019.01174
Yang WT, Wang Y, Shi YH, Fu H, Xu Z, Xu QQ, Zheng GQ. Herbal Compatibility of Ginseng and Rhubarb Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Injury of Rats. Front Physiol. 2019 Sep 13;10:1174. doi: 10.3389/fphys.2019.01174. eCollection 2019. PMID: 31572219; PMCID: PMC6753204.
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High Frequency Oscillations in Rat Hippocampal Slices: Origin, Frequency Characteristics, and Spread.

Frontiers in neurology

Naggar I, Stewart M, Orman R.
PMID: 32390935
Front Neurol. 2020 Apr 22;11:326. doi: 10.3389/fneur.2020.00326. eCollection 2020.

Field potential oscillations reflect repetitive firing and synaptic activity by ensembles of neurons in certain areas of the brain. They can be distinguished as slow (e.g., alpha, delta, and theta), fast (e.g., beta and gamma), and high frequency oscillations...

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Naggar I, Stewart M, Orman R. High Frequency Oscillations in Rat Hippocampal Slices: Origin, Frequency Characteristics, and Spread. Front Neurol. 2020;11:326doi: 10.3389/fneur.2020.00326.
Naggar, I., Stewart, M., & Orman, R. (2020). High Frequency Oscillations in Rat Hippocampal Slices: Origin, Frequency Characteristics, and Spread. Frontiers in neurology, 11326. https://doi.org/10.3389/fneur.2020.00326
Naggar, Isaac, et al. "High Frequency Oscillations in Rat Hippocampal Slices: Origin, Frequency Characteristics, and Spread." Frontiers in neurology vol. 11 (2020): 326. doi: https://doi.org/10.3389/fneur.2020.00326
Naggar I, Stewart M, Orman R. High Frequency Oscillations in Rat Hippocampal Slices: Origin, Frequency Characteristics, and Spread. Front Neurol. 2020 Apr 22;11:326. doi: 10.3389/fneur.2020.00326. eCollection 2020. PMID: 32390935; PMCID: PMC7188778.
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Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply.

Redox biology

Zhang H, Li C, Wen D, Li R, Lu S, Xu R, Tang Y, Sun Y, Zhao X, Pan M, Ma B.
PMID: 34929573
Redox Biol. 2021 Dec 17;49:102215. doi: 10.1016/j.redox.2021.102215. Epub 2021 Dec 17.

In mammalian ovaries, oocytes are physically coupled to somatic granulosa cells, and this coupling is crucial for the growth and development of competent oocytes as it mediates the transfer of metabolic support molecules. However, aging-mediated dysregulation in communication between...

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Zhang H, Li C, Wen D, et al. Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply. Redox Biol. 2021;49:102215doi: 10.1016/j.redox.2021.102215.
Zhang, H., Li, C., Wen, D., Li, R., Lu, S., Xu, R., Tang, Y., Sun, Y., Zhao, X., Pan, M., & Ma, B. (2021). Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply. Redox biology, 49102215. https://doi.org/10.1016/j.redox.2021.102215
Zhang, Hui, et al. "Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply." Redox biology vol. 49 (2021): 102215. doi: https://doi.org/10.1016/j.redox.2021.102215
Zhang H, Li C, Wen D, Li R, Lu S, Xu R, Tang Y, Sun Y, Zhao X, Pan M, Ma B. Melatonin improves the quality of maternally aged oocytes by maintaining intercellular communication and antioxidant metabolite supply. Redox Biol. 2021 Dec 17;49:102215. doi: 10.1016/j.redox.2021.102215. Epub 2021 Dec 17. PMID: 34929573.
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Muscular pain during therapy with carbenoxolone (Biogastrone).

British medical journal

Morgan TN, Donald I, McAndrew GM.
PMID: 27111921
Br Med J. 1966 Jul 02;2(5504):48. doi: 10.1136/bmj.2.5504.48-a.

No abstract available.

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Morgan TN, Donald I, McAndrew GM. Muscular pain during therapy with carbenoxolone (Biogastrone). Br Med J. 1966;2(5504):48doi: 10.1136/bmj.2.5504.48-a.
Morgan, T. N., Donald, I., & McAndrew, G. M. (1966). Muscular pain during therapy with carbenoxolone (Biogastrone). British medical journal, 2(5504), 48. https://doi.org/10.1136/bmj.2.5504.48-a
Morgan, T N, et al. "Muscular pain during therapy with carbenoxolone (Biogastrone)." British medical journal vol. 2,5504 (1966): 48. doi: https://doi.org/10.1136/bmj.2.5504.48-a
Morgan TN, Donald I, McAndrew GM. Muscular pain during therapy with carbenoxolone (Biogastrone). Br Med J. 1966 Jul 02;2(5504):48. doi: 10.1136/bmj.2.5504.48-a. PMID: 27111921; PMCID: PMC1942959.
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Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps .

Frontiers in veterinary science

Alarcón P, Manosalva C, Quiroga J, Belmar I, Álvarez K, Díaz G, Taubert A, Hermosilla C, Carretta MD, Burgos RA, Hidalgo MA.
PMID: 32582772
Front Vet Sci. 2020 Jun 05;7:260. doi: 10.3389/fvets.2020.00260. eCollection 2020.

Non-esterified fatty acids (NEFAs) such as oleic acid (OA) and linoleic acid (LA) are associated with a higher incidence of infectious diseases such as metritis and mastitis during the bovine peripartum. Fatty acids can induce an increase in the...

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Alarcón P, Manosalva C, Quiroga J, et al. Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps . Front Vet Sci. 2020;7:260doi: 10.3389/fvets.2020.00260.
Alarcón, P., Manosalva, C., Quiroga, J., Belmar, I., Álvarez, K., Díaz, G., Taubert, A., Hermosilla, C., Carretta, M. D., Burgos, R. A., & Hidalgo, M. A. (2020). Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps . Frontiers in veterinary science, 7260. https://doi.org/10.3389/fvets.2020.00260
Alarcón, Pablo, et al. "Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps ." Frontiers in veterinary science vol. 7 (2020): 260. doi: https://doi.org/10.3389/fvets.2020.00260
Alarcón P, Manosalva C, Quiroga J, Belmar I, Álvarez K, Díaz G, Taubert A, Hermosilla C, Carretta MD, Burgos RA, Hidalgo MA. Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps . Front Vet Sci. 2020 Jun 05;7:260. doi: 10.3389/fvets.2020.00260. eCollection 2020. PMID: 32582772; PMCID: PMC7291836.
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Showing 1 to 12 of 74 entries