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Showing 1 to 8 of 8 entries
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Stereospecificity of myofibrillar calcium sensitivity and PDE inhibition in cardiotonic thiadiazinones.

European journal of medicinal chemistry

Nadler G, Delimoge I, Lahouratate P, Leger I, Morvan M, Zimmermann R.
PMID: 22026936
Eur J Med Chem. 1996;31(10):805-12. doi: 10.1016/0223-5234(96)83974-2.

In pyridazinone or thiadiazinone cardiotonic agents with one chiral centre, the PDE inhibitory action resides mainly in one enantiomer and the myofibrillar calcium sensitization mainly in the other. This phenomenon is observed when the chiral centre is located on...

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Nadler G, Delimoge I, Lahouratate P, et al. Stereospecificity of myofibrillar calcium sensitivity and PDE inhibition in cardiotonic thiadiazinones. Eur J Med Chem. 1996;31(10):805-12doi: 10.1016/0223-5234(96)83974-2.
Nadler, G., Delimoge, I., Lahouratate, P., Leger, I., Morvan, M., & Zimmermann, R. (1996). Stereospecificity of myofibrillar calcium sensitivity and PDE inhibition in cardiotonic thiadiazinones. European journal of medicinal chemistry, 31(10), 805-12. https://doi.org/10.1016/0223-5234(96)83974-2
Nadler, G, et al. "Stereospecificity of myofibrillar calcium sensitivity and PDE inhibition in cardiotonic thiadiazinones." European journal of medicinal chemistry vol. 31,10 (1996): 805-12. doi: https://doi.org/10.1016/0223-5234(96)83974-2
Nadler G, Delimoge I, Lahouratate P, Leger I, Morvan M, Zimmermann R. Stereospecificity of myofibrillar calcium sensitivity and PDE inhibition in cardiotonic thiadiazinones. Eur J Med Chem. 1996;31(10):805-12. doi: 10.1016/0223-5234(96)83974-2. PMID: 22026936.
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Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria.

Iranian journal of basic medical sciences

Hosseini A, Shafiee-Nick R, Sadeghian H, Parsaee H.
PMID: 28868120
Iran J Basic Med Sci. 2017 Jun;20(6):639-647. doi: 10.22038/IJBMS.2017.8831.

OBJECTIVES: Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect comparable to that of IBMX (3-isobutyl-1-methylxanthine), a non-selective PDE inhibitor, but with differential chronotropic effect....

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Hosseini A, Shafiee-Nick R, Sadeghian H, et al. Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria. Iran J Basic Med Sci. 2017;20(6):639-647doi: 10.22038/IJBMS.2017.8831.
Hosseini, A., Shafiee-Nick, R., Sadeghian, H., & Parsaee, H. (2017). Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria. Iranian journal of basic medical sciences, 20(6), 639-647. https://doi.org/10.22038/IJBMS.2017.8831
Hosseini, Azar, et al. "Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria." Iranian journal of basic medical sciences vol. 20,6 (2017): 639-647. doi: https://doi.org/10.22038/IJBMS.2017.8831
Hosseini A, Shafiee-Nick R, Sadeghian H, Parsaee H. Novel cilostamide analogs, phosphodiesterase 3 inhibitors, produce positive inotropic but differential lusitropic and chronotropic effects on isolated rat atria. Iran J Basic Med Sci. 2017 Jun;20(6):639-647. doi: 10.22038/IJBMS.2017.8831. PMID: 28868120; PMCID: PMC5569452.
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Management of Cardio-Renal Syndrome and Diuretic Resistance.

Current treatment options in cardiovascular medicine

Verbrugge FH, Mullens W, Tang WH.
PMID: 26803318
Curr Treat Options Cardiovasc Med. 2016 Feb;18(2):11. doi: 10.1007/s11936-015-0436-4.

OPINION STATEMENT: Diuretic resistance in acute heart failure has emerged as a powerful predictor of adverse outcome, which is often independent of underlying glomerular filtration rate (GFR). Metrics of diuretic efficacy differ in their accuracy, convenience, and biological plausibility,...

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Verbrugge FH, Mullens W, Tang WH. Management of Cardio-Renal Syndrome and Diuretic Resistance. Curr Treat Options Cardiovasc Med. 2016;18(2):11doi: 10.1007/s11936-015-0436-4.
Verbrugge, F. H., Mullens, W., & Tang, W. H. (2016). Management of Cardio-Renal Syndrome and Diuretic Resistance. Current treatment options in cardiovascular medicine, 18(2), 11. https://doi.org/10.1007/s11936-015-0436-4
Verbrugge, Frederik H, et al. "Management of Cardio-Renal Syndrome and Diuretic Resistance." Current treatment options in cardiovascular medicine vol. 18,2 (2016): 11. doi: https://doi.org/10.1007/s11936-015-0436-4
Verbrugge FH, Mullens W, Tang WH. Management of Cardio-Renal Syndrome and Diuretic Resistance. Curr Treat Options Cardiovasc Med. 2016 Feb;18(2):11. doi: 10.1007/s11936-015-0436-4. PMID: 26803318.
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Precision Medicine Considerations for the Management of Heart Disease and Stroke in East Asians.

Cardiology plus

Goodnough CL, Gross ER.
PMID: 33954271
Cardiol Plus. 2020 Jul-Sep;5(3):101-108. doi: 10.4103/cp.cp_17_20. Epub 2020 Sep 30.

Heart disease is the leading cause of death in Asian Americans. Importantly, people of East Asian descent are more likely to carry a loss-of-function point mutation in aldehyde dehydrogenase 2 (ALDH2), ALDH2*2, which reduces ALDH2 enzymatic activity by at...

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Goodnough CL, Gross ER. Precision Medicine Considerations for the Management of Heart Disease and Stroke in East Asians. Cardiol Plus. 2020;5(3):101-108doi: 10.4103/cp.cp_17_20.
Goodnough, C. L., & Gross, E. R. (2020). Precision Medicine Considerations for the Management of Heart Disease and Stroke in East Asians. Cardiology plus, 5(3), 101-108. https://doi.org/10.4103/cp.cp_17_20
Goodnough, Candida L, and Gross, Eric R. "Precision Medicine Considerations for the Management of Heart Disease and Stroke in East Asians." Cardiology plus vol. 5,3 (2020): 101-108. doi: https://doi.org/10.4103/cp.cp_17_20
Goodnough CL, Gross ER. Precision Medicine Considerations for the Management of Heart Disease and Stroke in East Asians. Cardiol Plus. 2020 Jul-Sep;5(3):101-108. doi: 10.4103/cp.cp_17_20. Epub 2020 Sep 30. PMID: 33954271; PMCID: PMC8095722.
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Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States.

Journal of cardiac failure

Gottlieb SS, Psotka MA, Desai N, Lindenfeld J, Russo P, Allen LA.
PMID: 34265464
J Card Fail. 2021 Nov;27(11):1276-1279. doi: 10.1016/j.cardfail.2021.06.015. Epub 2021 Jul 12.

BACKGROUND: Outpatient calcitrope infusions-that is, the cardiac inotropes milrinone and dobutamine-are often used for bridge to transplantation and palliation in advanced heart failure, but few data exist about the real-world use of these agents.METHODS AND RESULTS: We used the...

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Gottlieb SS, Psotka MA, Desai N, et al. Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States. J Card Fail. 2021;27(11):1276-1279doi: 10.1016/j.cardfail.2021.06.015.
Gottlieb, S. S., Psotka, M. A., Desai, N., Lindenfeld, J., Russo, P., & Allen, L. A. (2021). Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States. Journal of cardiac failure, 27(11), 1276-1279. https://doi.org/10.1016/j.cardfail.2021.06.015
Gottlieb, Stephen S, et al. "Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States." Journal of cardiac failure vol. 27,11 (2021): 1276-1279. doi: https://doi.org/10.1016/j.cardfail.2021.06.015
Gottlieb SS, Psotka MA, Desai N, Lindenfeld J, Russo P, Allen LA. Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States. J Card Fail. 2021 Nov;27(11):1276-1279. doi: 10.1016/j.cardfail.2021.06.015. Epub 2021 Jul 12. PMID: 34265464.
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Depressant Effects of Prostacyclin in Human Atrial Fibers and Cardiomyocytes.

Journal of biomedical science

Lin CI, Loh SH, Luk HN, Wei J.
PMID: 11725017
J Biomed Sci. 1994 Mar;1(2):139-146. doi: 10.1007/BF02257988.

The aim of this study was to characterize the electropharmacological effects of prostacyclin (PGI(2)) in human atrial fibers and cardiomyocytes. Atrial tissues obtained from the hearts of 28 patients undergoing corrective cardiac surgery were used. Transmembrane action potentials were...

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Lin CI, Loh SH, Luk HN, et al. Depressant Effects of Prostacyclin in Human Atrial Fibers and Cardiomyocytes. J Biomed Sci. 1994;1(2):139-146doi: 10.1007/BF02257988.
Lin, C. I., Loh, S. H., Luk, H. N., & Wei, J. (1994). Depressant Effects of Prostacyclin in Human Atrial Fibers and Cardiomyocytes. Journal of biomedical science, 1(2), 139-146. https://doi.org/10.1007/BF02257988
Lin, C.-I., et al. "Depressant Effects of Prostacyclin in Human Atrial Fibers and Cardiomyocytes." Journal of biomedical science vol. 1,2 (1994): 139-146. doi: https://doi.org/10.1007/BF02257988
Lin CI, Loh SH, Luk HN, Wei J. Depressant Effects of Prostacyclin in Human Atrial Fibers and Cardiomyocytes. J Biomed Sci. 1994 Mar;1(2):139-146. doi: 10.1007/BF02257988. PMID: 11725017.
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Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics.

Biomolecules

Kumavath R, Paul S, Pavithran H, Paul MK, Ghosh P, Barh D, Azevedo V.
PMID: 34572488
Biomolecules. 2021 Aug 25;11(9). doi: 10.3390/biom11091275.

Cardiac glycosides are natural sterols and constitute a group of secondary metabolites isolated from plants and animals. These cardiotonic agents are well recognized and accepted in the treatment of various cardiac diseases as they can increase the rate of...

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Kumavath R, Paul S, Pavithran H, et al. Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics. Biomolecules. 2021;11(9)doi: 10.3390/biom11091275.
Kumavath, R., Paul, S., Pavithran, H., Paul, M. K., Ghosh, P., Barh, D., & Azevedo, V. (2021). Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics. Biomolecules, 11(9), . https://doi.org/10.3390/biom11091275
Kumavath, Ranjith, et al. "Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics." Biomolecules vol. 11,9 (2021). doi: https://doi.org/10.3390/biom11091275
Kumavath R, Paul S, Pavithran H, Paul MK, Ghosh P, Barh D, Azevedo V. Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics. Biomolecules. 2021 Aug 25;11(9). doi: 10.3390/biom11091275. PMID: 34572488; PMCID: PMC8465509.
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Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States.

Journal of cardiac failure

Gottlieb SS, Psotka MA, Desai N, Lindenfeld J, Russo P, Allen LA.
PMID: 34265464
J Card Fail. 2021 Nov;27(11):1276-1279. doi: 10.1016/j.cardfail.2021.06.015. Epub 2021 Jul 12.

BACKGROUND: Outpatient calcitrope infusions-that is, the cardiac inotropes milrinone and dobutamine-are often used for bridge to transplantation and palliation in advanced heart failure, but few data exist about the real-world use of these agents.METHODS AND RESULTS: We used the...

Cite
Gottlieb SS, Psotka MA, Desai N, et al. Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States. J Card Fail. 2021;27(11):1276-1279doi: 10.1016/j.cardfail.2021.06.015.
Gottlieb, S. S., Psotka, M. A., Desai, N., Lindenfeld, J., Russo, P., & Allen, L. A. (2021). Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States. Journal of cardiac failure, 27(11), 1276-1279. https://doi.org/10.1016/j.cardfail.2021.06.015
Gottlieb, Stephen S, et al. "Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States." Journal of cardiac failure vol. 27,11 (2021): 1276-1279. doi: https://doi.org/10.1016/j.cardfail.2021.06.015
Gottlieb SS, Psotka MA, Desai N, Lindenfeld J, Russo P, Allen LA. Use of Outpatient Intravenous Calcitropes for Heart Failure in the United States. J Card Fail. 2021 Nov;27(11):1276-1279. doi: 10.1016/j.cardfail.2021.06.015. Epub 2021 Jul 12. PMID: 34265464.
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Showing 1 to 8 of 8 entries